Published by De Gruyter

Volume 27 Issue 1 - Special Issue: NFDI – Nationale Forschungsdateninfrastruktur; Guest Editor: Thomas Wachtler

Issue of Neuroforum

Contents
Journal Overview

Publicly Available March 8, 2021

Editorial

January 19, 2021

Editorial

Michael Denker, Alexandra Stein, Thomas Wachtler

Page range: 1-2

Review articles

Open Access January 12, 2021

NFDI-Neuro: building a community for neuroscience research data management in Germany

Thomas Wachtler, Pavol Bauer, Michael Denker, Sonja Grün, Michael Hanke, Jan Klein, Steffen Oeltze-Jafra, Petra Ritter, Stefan Rotter, Hansjörg Scherberger, Alexandra Stein, Otto W. Witte

Page range: 3-15

More Download PDF

Abstract

Increasing complexity and volume of research data pose increasing challenges for scientists to manage their data efficiently. At the same time, availability and reuse of research data are becoming more and more important in modern science. The German government has established an initiative to develop research data management (RDM) and to increase accessibility and reusability of research data at the national level, the Nationale Forschungsdateninfrastruktur (NFDI). The NFDI Neuroscience (NFDI-Neuro) consortium aims to represent the neuroscience community in this initiative. Here, we review the needs and challenges in RDM faced by researchers as well as existing and emerging solutions and benefits, and how the NFDI in general and NFDI-Neuro specifically can support a process for making these solutions better available to researchers. To ensure development of sustainable research data management practices, both technical solutions and engagement of the scientific community are essential. NFDI-Neuro is therefore focusing on community building just as much as on improving the accessibility of technical solutions.

Open Access January 11, 2021

In defense of decentralized research data management

Michael Hanke, Franco Pestilli, Adina S. Wagner, Christopher J. Markiewicz, Jean-Baptiste Poline, Yaroslav O. Halchenko

Page range: 17-25

More Download PDF

Abstract

Decentralized research data management (dRDM) systems handle digital research objects across participating nodes without critically relying on central services. We present four perspectives in defense of dRDM, illustrating that, in contrast to centralized or federated research data management solutions, a dRDM system based on heterogeneous but interoperable components can offer a sustainable, resilient, inclusive, and adaptive infrastructure for scientific stakeholders: An individual scientist or laboratory, a research institute, a domain data archive or cloud computing platform, and a collaborative multisite consortium. All perspectives share the use of a common, self-contained, portable data structure as an abstraction from current technology and service choices. In conjunction, the four perspectives review how varying requirements of independent scientific stakeholders can be addressed by a scalable, uniform dRDM solution and present a working system as an exemplary implementation.

Open Access January 12, 2021

Reproducibility and efficiency in handling complex neurophysiological data

Michael Denker, Sonja Grün, Thomas Wachtler, Hansjörg Scherberger

Page range: 27-34

More Download PDF

Abstract

Preparing a neurophysiological data set with the aim of sharing and publishing is hard. Many of the available tools and services to provide a smooth workflow for data publication are still in their maturing stages and not well integrated. Also, best practices and concrete examples of how to create a rigorous and complete package of an electrophysiology experiment are still lacking. Given the heterogeneity of the field, such unifying guidelines and processes can only be formulated together as a community effort. One of the goals of the NFDI-Neuro consortium initiative is to build such a community for systems and behavioral neuroscience. NFDI-Neuro aims to address the needs of the community to make data management easier and to tackle these challenges in collaboration with various international initiatives (e.g., INCF, EBRAINS). This will give scientists the opportunity to spend more time analyzing the wealth of electrophysiological data they leverage, rather than dealing with data formats and data integrity.

January 18, 2021

Research data management in clinical neuroscience: the national research data infrastructure initiative

Carsten M. Klingner, Petra Ritter, Stefan Brodoehl, Christian Gaser, André Scherag, Daniel Güllmar, Felix Rosenow, Ulf Ziemann, Otto W. Witte

Page range: 35-43

Abstract

In clinical neuroscience, there are considerable difficulties in translating basic research into clinical applications such as diagnostic tools or therapeutic interventions. This gap, known as the “valley of death,” was mainly attributed to the problem of “small numbers” in clinical neuroscience research, i.e. sample sizes that are too small (Hutson et al., 2017). As a possible solution, it has been repeatedly suggested to systematically manage research data to provide long-term storage, accessibility, and federate data. This goal is supported by a current call of the DFG for a national research data infrastructure (NFDI). This article will review current challenges and possible solutions specific to clinical neuroscience and discuss them in the context of other national and international health data initiatives. A successful NFDI consortium will help to overcome not only the “valley of death” but also promises a path to individualized medicine by enabling big data to produce generalizable results based on artificial intelligence and other methods.

Nachrichten aus der Gesellschaft

February 16, 2021

Nachrichten aus der Gesellschaft

Page range: 45-49

Publicly Available April 25, 2021

Supplement (online only): Proceedings of the 14th Göttingen Meeting of the German Neuroscience Society 2021

Article number: 20212003

Download PDF

About this journal

This journal has ceased publication. Neuroforum was published from 1995 till 2022. It was the official journal of the German Neuroscience Society (GNS) / Neurowissenschaftliche Gesellschaft e.V. (NWG).
The main scientific articles of Neuroforum will appear in solely electronic form on the web portal dasGehirn.info (https://www.dasgehirn.info/) starting in 2023.

Volume 27 Issue 1 - Special Issue: NFDI – Nationale Forschungsdateninfrastruktur; Guest Editor: Thomas Wachtler

Issue of Neuroforum

Frontmatter

Editorial

NFDI-Neuro: building a community for neuroscience research data management in Germany

Abstract

In defense of decentralized research data management

Abstract

Reproducibility and efficiency in handling complex neurophysiological data

Abstract

Research data management in clinical neuroscience: the national research data infrastructure initiative

Abstract

Nachrichten aus der Gesellschaft

Supplement (online only): Proceedings of the 14th Göttingen Meeting of the German Neuroscience Society 2021