journal: Reviews in Analytical Chemistry

Impact Factor: 2.458

Open Access Published since June 1, 1981

Reviews in Analytical Chemistry

ISSN: 2191-0189

Editor-in-chief: Israel Schechter

Managing Editor: Krzysztof Dębniak

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About this journal

Reviews in Analytical Chemistry is an open access journal. From March 1, 2021 publication costs are covered by so called Article Processing Charges(APC), paid by authors' affiliated institutions, funders or sponsors. New manuscripts are subject to APC. APC is reduced by 30% (APC = 700 EUR) for all new, regular manuscripts submitted from October 1, 2022.

New Voucher System for Reviewers is now available in Reviews in Analytical Chemistry. For details, please see here.

Objective
Reviews in Analytical Chemistry publishes authoritative reviews by leading experts in the dynamic field of chemical analysis. The subjects can encompass all branches of modern analytical chemistry such as spectroscopy, chromatography, mass spectrometry, electrochemistry and trace analysis and their applications to areas such as environmental control, pharmaceutical industry, automation and other relevant areas. Review articles bring the expert up to date in a concise manner and provide researchers an overview of new techniques and methods.

Topics

Analytical chemistry
Analytical spectroscopy and optical detection methods
Analytical electrochemistry
Separation sciences and their analytical applications
Mass spectrometry
Chemical sensors
Trace analysis and particulate matter analysis
Surface analysis and chemical imaging
Chemometry

Article formats
Review Article, Research Article, Rapid Communication, Commentary, Letter, Erratum

> Information on submission process

Special Issues:

"Nanomaterials with mimetic enzymatic properties for label-free sensors and biosensors"
Guest Editors: Prof. Gang Wei (Qingdao University, China) and Prof. Zhiqiang Su (Beijing University of Chemical Technology, China)
Submission deadline: December 31, 2022

Your Benefits

Cutting-edge techniques and methods in the field of chemical analysis
Rapid ahead-of-print online publication times
Leading experts in the subject
High quality peer-review

History

Reviews in Analytical Chemistry was previously published by Freund Publishing House Ltd.

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Volume 42 Issue 1

January 2023

Research Article

Open Access May 12, 2023

Detection of exosomes in various biological fluids utilizing specific epitopes and directed multiple antigenic peptide antibodies

Dikshita Panwar, Deepali Shrivastava, Shalaka Bhawal, Lavleen Kumar Gupta, N. S. Sampath Kumar, Anjani Devi Chintagunta

Article number: 20230056

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Abstract

Exosomes are nanosized cell-derived vesicles that have recently gained attention for their use as a biomarker since the biomolecules encountered in these vesicles are directly linked to specific diseases including immuno-inflammatory, cardiovascular, and hepatic disorders. Furthermore, due to their nano size and safe travel in extracellular fluids, exosomes have been investigated as natural drug delivery systems, delivering cargo to destined cells with excellent specificity and efficiency, and crossing the blood–brain barrier. This necessitates the isolation and detection of exosomes. However, numerous exosome isolation techniques are available, including ultracentrifugation, size-based chromatography, polymer precipitation, microfluidics, and immunoaffinity-based isolation, with the downfalls of non-specificity and lower cost-effectiveness. This article introduces an immunoaffinity-based detection of exosomes using targeted anti-exosome antibodies raised in chickens due to its economic and commercial viability. The current study is unique in that it identified a specific antigenic region on exosomal surface tetraspanins (CD9, CD63, CD81) and constructed a multiple antigenic peptide dendrimer for making a small peptide as an immunogen without the use of a carrier protein. The antigenic region selection is critical to the study because it determines the efficiency of antibodies for exosome capture. This technique was validated using enzyme-linked immunosorbent assay in various biological fluids such as serum, urine, milk, plasma, and blood due to its numerous advantages including high sensitivity, specificity, handling multiple samples at once, requiring a small sample amount, and no purification as an antigen. In light of this technique, it is a useful tool for clinical monitoring of the patient’s biological conditions. Graphical abstract

Review Articles

Open Access February 16, 2023

Progress of sensitive materials in chemiresistive sensors for detecting chemical warfare agent simulants: A review

Liu Yang, Molin Qin, Genwei Zhang, Jie Yang, Junchao Yang, Jiang Zhao

Article number: 20220052

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Abstract

Chemical warfare agents (CWAs) are chemical substances intended for use in military operations to kill, injure, or incapacitate an enemy. It is very important to detect toxic CWAs at trace levels on site. Compared with traditional CWA analysis instrument methods, chemiresistive gas sensors present advantages of being small, fast, and inexpensive. Chemiresistive gas sensors are still an important research topic with the development of nanofabrication technology and new kinds of sensing materials, including carbon nanotubes, graphene, and black phosphorus (BP). Chemiresistive gas sensors are divided into three categories according to the type of sensitive materials: carbon- and BP-based materials, conductive polymers, and metal oxide semiconductors. A brief analysis was carried out on fabrication strategies using sensitive materials, including hydrogen bonding strategies, nanostructures, morphology, doping effects, composite materials, and other material application methods, and the sensitive materials and detection effects are summarized in this study. This review aims to provide guidance in the development of chemiresistive sensors for the detection of CWAs. Graphical abstract

Open Access March 29, 2023

Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis

Mahmoud Tareq Abdelwahed, Maha A. Hegazy, Ekram H. Mohamed

Article number: 20220055

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Abstract

Ashwagandha ( Withania somnifera ) is a very popular medicinal herb originated mainly in India and found in the Middle East and parts of Africa. Ashwagandha has gained recognition as the most revered plant in Ayurvedic medicine. Studies indicated that it is used as anxiolytic, anti-inflammatory, antioxidant, adaptogen, memory enhancer, and possess an effect on neurodegenerative diseases. Additionally, it was revealed that the plant exerts antibacterial, antiviral, antitumor, aphrodisiac, and cardiovascular protection activities. Due to the biological and nutritional importance of nutraceuticals, particularly ashwagandha, and as part of the ongoing research of the natural products and its bioactive phytochemicals, this review aims to summarize the recent analytical techniques that have been reported for the determination of different chemical constituents of Withania somnifera quantitatively and qualitatively, and to highlight new challenges.

Open Access April 19, 2023

A brief review of the application of microextraction by packed sorbent for antibiotics analysis from biological, food, and environmental samples

Graciela Granados-Guzmán, Mónica Díaz-Hernández, Rocío Alvarez-Román, Norma Cavazos-Rocha, Omar J. Portillo-Castillo

Article number: 20230057

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Abstract

Currently, sample preparation is the most laborious part of the analytical process, requiring the most time and being susceptible to the most errors. In this context, numerous investigations have focused on the miniaturization of these techniques to reduce work time, costs, and errors. In this regard, microextraction by packed sorbent (MEPS) is a simple, fast, and robust sample preparation technique suitable for easy automation in several analytical systems and is applied to a wide variety of samples. Antibiotics are among the most commonly used drugs; however, their extensive and inappropriate use has garnered significant attention in the environment, human health, and food safety. This brief review is intended to provide an overview of recently reported antibiotic extraction methods based on MEPS, with a special interest in those applied to the analysis of biological, environmental, and food samples. In addition, the sample pretreatment step before extraction by the MEPS device was highlighted, as was the description of the sample-related steps within the MEPS procedure, such as extraction, washing, and elution.

Volume 38 (2019)

Volume 37 (2018)

Volume 36 (2017)

Volume 35 (2016)

Volume 34 (2015)

Volume 33 (2014)

Volume 32 (2013)

Volume 31 (2012)

Volume 30 (2011)

Volume 29 (2010)

Volume 28 (2009)

Volume 27 (2008)

Volume 26 (2007)

Volume 25 (2006)

Volume 24 (2005)

Volume 23 (2004)

Volume 22 (2003)

Volume 21 (2002)

Volume 20 (2001)

Volume 19 (2000)

Volume 18 (1999)

Volume 17 (1998)

Volume 16 (1997)

Volume 15 (1996)

Volume 14 (1995)

Volume 13 (1994)

Volume 12 (1993)

Volume 11 (1992)

Volume 10 (1991)

Volume 9 (1989)

Volume 8 (1986)

Volume 7 (1983)

Volume 6 (1982)

Volume 5 (1981)

Volume 4 (1980)

Issue 4

5-year Impact Factor	4.475
Cite Score	3.3
Impact Factor	2.458
Journal Citation Indicator	0.39
SCImago Journal Rank	0.532
Source Normalized Impact per Paper	0.790

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Editorial

Editor-in-Chief
Prof. Israel Schechter
Schulich Faculty of Chemistry
Technion - Israel Institute of Technology
Haifa 32000, Israel

Associate Editors:
Prof. Claudio Baggiani (Department of Chemistry, University of Turin, Italy)
Dr. Jessica Brandi (Department of Biotechnology, University of Verona, Italy)
Prof. Julia Martin Bueno (Department of Analytical Chemistry, University of Seville, Spain)
Dr. Calum Morrison (Department of Applied Science, Glasgow Caledonian University, UK)
Dr. Fabio Di Nardo (Department of Chemistry, University of Turin, Italy)
Prof. Joseph Genereux (Department of Chemistry, University of California, Riverside, USA)
Prof. Demetrio Milea (CHIBIOFARAM Department, University of Messina, Italy)
Prof. Jesus Simal-Gandara (Department of Analytical Chemistry and Food Science, University of Vigo, Spain)
Prof. Yuliang Li (School of Environmental Science and Engineering, Chang'an University, China)

Language Editors:
Dr. Ramila Amirikas (the ōbex project)
Dr. Susan Brittain (the ōbex project)
Heidi Huttunen-Hennelly
Victoria F. Guarisco

Editorial Board:
Prof. Edwin De Pauw (Department of Chemistry, University of Liege, Belgium)
Prof. Mattanjah S. de Vries (Department of Chemistry and Biochemistry, University of California, Santa Barbara, USA)
Prof. Javier J. Laserna (Department of Analytical Chemistry, University of Málaga, Spain)
Prof. Stuart Licht (Department of Chemistry, Columbian College of Arts and Sciences, USA)
Prof. David M. Lubman (Department of Surgery Research, University of Michigan, USA)
Prof. Daniel Mandler (Institute of Chemistry, The Hebrew University of Jerusalem, Israel)
Prof. Vincenzo Palleschi (Institute of Chemistry of Organometallic Compounds, National Research Council, Italy)
Prof. Michael Sigman (Department of Chemistry, University of Central Florida, USA)
Prof. George M. Whitesides (Department of Chemistry and Chemical Biology, Harvard University, USA)

Editorial Office
Dr. Krzysztof Dębniak
Managing Editor
EditorialRevAnalChem@degruyter.com

Publisher
DE GRUYTER Poland
Bogumiła Zuga 32A Str.
01-811 Warsaw, Poland
T: +48 22 701 50 15

(Deutsch)

Type: Journal
Language: English
Publisher: De Gruyter
First published: June 1, 1981
Publication Frequency: 1 Issue per Year
Audience: Analytical chemists in academia and industry
Keywords: Analytical Chemistry; Spectroscopy; Electrochemistry; Chromatography; Trace Analysis