Published by De Gruyter

Volume 3 Issue 3

Issue of Scandinavian Journal of Pain

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Contents
Journal Overview

Abstract

Aim To evaluate the long-term efficacy of two different treatment programmes for medication-overuse headache (MOH) in so-called treatment-resistant patients. Methods MOH patients, who had previously been unsuccessfully treated by neurologists, were enrolled in one of 2 structured detoxification programmes in a tertiary headache centre: (A) a one-week withdrawal with restricted analgesics, rescue medications and prophylactics from Day 1 followed by advice of restricted intake of symptomatic medications or (B) a 2-month drug-free period and multidisciplinary education in groups and subsequent initiation of restricted symptomatic medication and prophylactics as required. All patients were closely followed up for a year. Results 86 of 98 patients completed the 12-month follow-up. Totally, headache frequency was reduced by 39% ( p <0.001), medication use by 63% ( p <0.001) and 83% remained cured of MOH. Headache frequency was reduced with more than 50% in 42 patients (49%) and 52 (61%) reverted to episodic headache, and with no difference between the groups. Patients in programme B used significantly less symptomatic medication: 6.5 days/4 weeks compared with 8.7 days/4 weeks in programme A ( p = 0.02), and the 56% of patients in programme B who needed prophylactic medication was significantly less than the 80% in programme A ( p = 0.02). Further, programme B required fewer resources from the staff. Conclusion Structured detoxification with close follow-up by a multidisciplinary team for one year is highly effective in patients with previously treatment-resistant MOH. We recommend a multidisciplinary educational programme for patients in groups due to cost-effectiveness and limited use of medication.

About this journal

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Meet us at the 2022 Annual Meeting of the Scandinavian Association for the Study of Pain, 13-14th October, Rigshospitalet, Copenhagen!

Objective
The Scandinavian countries have a long and distinguished tradition of excellent scientific and medical contributions to pain research. Following this tradition, the Scandinavian Journal of Pain (SJPAIN) has been publishing internationally relevant articles on all aspects of pain since 2010. The journal is the official organ of the Scandinavian Association for the Study of Pain and serves as a comprehensive forum for original research on the nature of pain, pain mechanisms, and pain management. In order to bring pain-researchers and pain-clinicians up-to-date on important issues, the journal also encourages submissions of topical reviews.

Topics

Clinical Sciences: Acute Pain
Clinical Sciences: Cancer-related pain
Clinical Sciences: Chronic Pain
Clinical Sciences: Neuropathic Pain
Epidemiology, Omics and Economics of Pain
Experimental Pain
Methods, Measurements and Biostatistics
Neurobiology, Pharmacology and Basic Science
Nursing and Pain Management
Psychology of Pain and Pain Management

Article formats
Original articles (basic and clinical research), comprehensive systematic and topical reviews, hypothesis-generating case-reports and observational studies, short communications, letters to the Editor

Volume 3 Issue 3

Issue of Scandinavian Journal of Pain

Spontaneous pain is reduced by conditioning pain modulation in peripheral neuropathy but not in fibromyalgia—Implications for different pain mechanisms

Differential pain modulation in patients with peripheral neuropathic pain and fibromyalgia

Abstract

Pulsed radiofrequency—Time for a clinical pause and more science

Pulsed radiofrequency in peripheral posttraumatic neuropathic pain: A double blind sham controlled randomized clinical trial

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Phantom pains and sensations – how does it feel? Only the patient really knows

Phantom phenomena – Their perceived qualities and consequences from the patient’s perspective

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Impact of mental stressor on conditioned pain modulation

The effect of a mental stressor on conditioned pain modulation in healthy subjects

Abstract

Pharmacological modulation of chronic pain after whiplash injury

Whiplash Associated Disorders (WAD): Responses to pharmacological challenges and psychometric tests

Abstract

Why are autonomic responses to pressure pain different from those to heat pain and ischaemic pain?

Cardiovascular responses to and modulation of pressure pain sensitivity in normotensive, pain-free women

Abstract

Piriformis muscle injection guided by sciatic nerve stimulation: Quick, simple, and safe technique

Musculus piriformis syndrome: Localization and injection therapy—Comment to letter from Mayo-Moldes M et al. [1]

The “pain matrix” reloaded

Endpoints in animal pain models

Evaluating pain-related behavior in spinal cord injury

The role of the amygdala in sensory and emotional-like pain behavior in neuropathic animals

Peripheral and central pain mechanisms—From animal models to clinical research

Human experimental models of central sensitization—Do they bridge the gap between animal models and clinical observations?

Assessment of central sensitization in the clinic. Is it possible?

Migraine neurobiology and treatment

Chronic headaches–Goals and obstacles

Trigeminal neuralgia and other cranial neuralgias

Temporomandibular disorders: Pathophysiology and diagnosis

HIV-associated painful polyneuropathy

Keynote: Neuronal and glial signalling in pain neuroplasticity

Neuropathic pain—From guidelines to clinical practice

Postoperative pain treatment. What’s the evidence—And how to use it?

NSAIDs in postoperative pain

How should we prevent persistent postoperative pain?

Opioids: Genetics and receptors

Chronic pain and sleep disorders

Population-based studies on chronic pain: The role of opioids

Living beyond pain: Acceptance and commitment therapy

Modality specific alterations of esophageal sensitivity caused by longstanding diabetes mellitus

Abstract

Validation of a porcine behavioural model of UVB induced inflammatory pain

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Recovery after a lumbar disc herniation is dependent on a gender and OPRM1 Asn40Asp genotype interaction

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Pain sensitivity changes in chronic pain patients with and without spinal cord stimulation assessed by nociceptive withdrawal reflex thresholds and electrical pain thresholds

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Acceptance and commitment therapy for fibromyalgia: A randomized controlled trial

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Sortilins in neuropathic pain

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Systematic review of neuropathic component in persistent post-surgical pain

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Pain prevalence in a university hospital in Iceland

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The effect of tail-docking neonate piglets on ATF-3 and NR2B immunoreactivity in coccygeal dorsal root ganglia and spinal cord dorsal horn neurons: Preliminary data

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Na+/K+-ATPase dependent regulation of astrocyte Ca2+ signalling: A novel mechanism for modulation of long-term pain?

Abstract

Glutamate attenuates nitric oxide release from isolated trigeminal ganglion satellite glial cells

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Acute behavioural responses to tail docking in piglets – Effects of increasing docking length?

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Dose and administration-period play a key role in the effect of ceftriaxone on neuropathic pain in CCI-operated rats

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Translational aspects of rectal evoked potentials: A comparative study in rats and humans

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Time-course of analgesic effects of botulinum neurotoxin type A (BoNTA) on human experimental model of pain induced by injection of glutamate into temporalis muscle

Abstract

The effect of nerve compression and capsaicin on contact heat evoked potentials (CHEPs) related to Aδ and C fibers

Abstract

Effect of specific trapezius exercises vs. coordination training on corticomotor control of neck muscles

Abstract

SNP in TNFα T308G is predictive for persistent postoperative pain following inguinal hernia surgery

Abstract

Chronic pain in thoracotomy

Na⁺/K⁺-ATPase dependent regulation of astrocyte Ca²⁺ signalling: A novel mechanism for modulation of long-term pain?