This article provides a review of the latest experimental results in quantum physics and astrophysics, discussing their repercussions on the advanced physical theories that go beyond both the SMs (standard models) of particle physics and cosmology. It will be shown that many of the essential concepts of the advanced theoretical models developed over the past 40 years are no longer tenable because they are contradicting the novel data. Most recent results (December 2016) from the Large Hadron Collider revealed no new matter particles up to particle masses of 1.6 TeV/c 2 , which is in accordance with recent ACME experimental data (2014) that saw no electric dipole moment for the electron as predicted by these theories. Moreover, the LUX experiment (since 2013) did not see any dark matter particles either, thus independently supporting LHC and ACME measurements. Furthermore, experimental particle physics seems to be telling us that dark matter particles (LHC results) do not exist, suggesting that dark matter particles either are more exotic or are more difficult to detect than had been predicted in the past decades (less likely with recent LHC results). Astrophysical observations since 1933, starting with Caltech astronomer Zwicky, however, have provided irrefutable evidence for the existence of dark matter, for instance, based on the phenomenon of gravitational lensing as well as observed rotational velocities of stars orbiting the galactic center that are deviating from Newton’s law. Surprisingly, recent astronomical observations by Bidin, ESO (2010, 2012, 2014), seem to indicate the absence of dark matter within galaxies. In addition, cosmology at present has no explanation for about 68 % of the energy in the Universe that comes in the form of dark energy. Recently, measured data from three entirely different types of experiments both on earth and in space (2006–2011) are hinting at completely novel features of gravity that, if confirmed, must be outside Einstein’s general relativity. Extreme gravitomagnetic and gravity-like fields may have been observed at cryogenic temperatures generated by a rotating ring or disk. However, these experimental results are not conclusive so far. The strength of these extreme fields has been calculated and, according to the respective equations, should be sufficient to serve as a basis for a gravitational technology that, for example, could establish long sought field propulsion (i.e. propulsion without fuel), actively researched by physicists and rocket engineers in the 1960s and 1990s. This article concludes with an outlook on the novel technology of gravitational engineering that might follow from gravity-like fields and discusses the novel physical concepts resulting from the existence of these extreme gravitomagnetic fields.