Published by De Gruyter

Volume 71 Issue 4

Issue of Zeitschrift für Naturforschung B

Contents
Journal Overview

Publicly Available March 28, 2016

Frontmatter

Page range: i-iii

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Publicly Available March 28, 2016

In this Issue

Page range: i-iv

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Publicly Available January 20, 2016

Ferromagnetism in Fe_3−x−yNi_xGeTe₂

Juliane Stahl, Vladimir Pomjakushin, Dirk Johrendt

Page range: 273-276

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Abstract

Polycrystalline samples of Fe 3− y GeTe 2 (0.08 ≤ y ≤ 0.29) and the solid solutions Fe 3− x − y Ni x GeTe 2 (0.24 ≤ x ≤ 1.32; 0.14 ≤ y ≤ 0.41) were synthesized at 898–973 K in a resistance furnace and characterized by X-ray and neutron powder diffraction with Rietveld analysis (Fe 3 GeTe 2 type, P 6 3 / mmc , a = 402.665(3), c = 1632.820(14) pm for x = 0, y = 0.08). Fe 3 Ge layers with planar FeGe hexagons and additional iron atoms above and below the rings are separated by double layers of tellurium atoms. Fe 3 GeTe 2 is ferromagnetic below T C = 230 K with magnetic moments aligned along the c axis. T C depends on the iron content and decreases with increasing iron vacancies continuously to 153 K in Fe 2.71 GeTe 2 . Further reduction of T C is possible by nickel substitution until magnetic ordering is nearly absent in Fe 1.33 Ni 1.32 GeTe 2 . The suppression of the magnetic ordering is caused by random dilution of the magnetic iron atoms either by vacancies or by non-magnetic nickel atoms.

Publicly Available March 8, 2016

A novel potentiometric sensor based on urease/ bovine serum albumin-poly(3,4-ethylenedioxythiophene)/Pt for urea detection

Chien-Hsing Hsu, Ya-Wei Hsu, Yu-Ching Weng

Page range: 277-282

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Abstract

We have presented a potentiometric urea sensor using an urease/bovine serum albumin (BSA)-poly(3,4-ethylenedioxythiophene)(PEDOT)/Pt electrode. A urea detection sensitivity of 15.2 mV/decade (order of magnitude) has been achieved. BSA trapped in the PEDOT matrix was employed to bond urease molecules on the surface of a BSA-PEDOT/Pt electrode via amide bonds formed between the carboxyl functional groups on the enzyme and the amines on the BSA. The effects of PEDOT thickness, pH value of the urea solution, urease concentration, and temperature on the urea detection sensitivity were also studied. The lifetime of the sensor was studied for a period of 10 weeks, and the average sensing degradation rate was about 9 % per week. This sensor displayed a high selectivity to urea over glucose, KCl, and NaCl.

Publicly Available March 25, 2016

Two new glycosidal metabolites of endophytic fungus Penicillium sp. (NO.4) from Tapiscia sinensis

Qiao Wan, Ziwei Feng, Xueshuang Li, Mengmeng Lv, Zhiyong Guo, Zhangshuang Deng, Kun Zou

Page range: 283-286

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Abstract

Two new glycosides, 8- O - β- d -glucopyranosyl-6-methyl-1-carboxylate methyl ester xanthone ( 1 ) and 4′- O - β- d -galactopyranosyl djalonensone ( 2 ), together with four known compounds, 8-hydroxy-6-methyl-9-oxo-9 H -xanthene-1-carboxylate methyl ester ( 3 ), cassionllin ( 4 ), djalonensone ( 5 ) and alternariol ( 6 ), were isolated from the endophytic fungus Penicillium sp. (NO.4) of Tapiscia sinensis Oliv. The structures of compounds 1–6 were elucidated by the analysis of 1D and 2D NMR and HRMS. The cytotoxic activities of these compounds were evaluated against four cancer cell lines, as well as antimicrobial activities against two plant-pathogenic microbes. Compounds 1–6 showed moderate cytotoxicity against the A549 cancer cell line with IC 50 values ranging from 6.8 to 35.8 μg mL −1 and were found to be inactive against three other cancer cell lines MCF-7, Caski and Hep G-2.

Publicly Available March 23, 2016

New bioactive metabolites from Penicillium purpurogenum MM

Mohamed Shaaban, Mohammad Magdy El-Metwally, Hartmut Laatsch

Page range: 287-295

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Abstract

Three new bioactive compounds, namely ( S )-tenellic acid B dimethyl acetal ( 1a ), (3 R ,3′ R/S )-isotalarone ( 2 ), and (3 R ,5 R )- cis -5-methyl-3-(2-oxobutyl)-dihydrofuran-2-one ( 3 ), were isolated from the terrestrial fungus Penicillium purpurogenum MM, together with 15 known metabolites: talaroflavone, pestalasin A, altenuene, penicillide, 3′- O -methyl-dehydroisopenicillide, rubralactone, tenellic acid B, diaporthin, butyrolactone 1, butyrolactone-V, 4-hydroxy-2-methoxyacetanilide, ergosterol, ergosterol peroxide, linoleic acid, and glycerol monolinoleate. The chemical structures of the three new compounds were confirmed by extensive one- and two-dimensional NMR and electron spray ionization high-resolution mass spectra measurements and by comparison with literature data. The absolute configurations of the new compounds, and of talaroflavone ( 4a ) and tenellic acid B ( 2b ), were determined by ab initio calculations of ECD, ORD, and NMR data. The antimicrobial and cytotoxic activities of the crude extract and of the isolated compounds were studied using a set of microorganisms and brine shrimp assay, respectively. The isolation and taxonomic characterization of P. purpurogenum MM is reported.

Publicly Available March 9, 2016

Long-chain alkyl-substituted gentisic acid and benzoquinone derivatives from the root of Micronychia tsiramiramy (Anacardiaceae)

Andrianambinina A. Razakarivony, Bruno N. Lenta, Bakolinirina Andriamihaja, Carmela Michalek, Bakonirina Razanamahefa, Dorothée R. Razafimahefa, Maonja Finaritra Rakotondramanga, Rivoarison Randrianasolo, Alain Méli Lannang, Ralinandrianina Randriamiaramisaina, Fekam F. Boyom, Philip J. Rosenthal, Norbert Sewald

Page range: 297-303

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Abstract

A new gentisic acid derivative named micronyc acid ( 1 ) and a new 1,4-benzoquinone derivative named micronone ( 2 ) have been isolated from the root of Micronychia tsiramiramy together with the known compounds gallic acid ( 3 ), methyl gallate ( 4 ), moronic acid ( 5 ), masticadienolic acid ( 6 ), and masticadienediol ( 7 ). The structures of 1 and 2 were established using MS and NMR. Compound 1 was tested for antiplasmodial activity in vitro against the chloroquine-resistant strain Plasmodium falciparum W2 and displayed moderate antiplasmodial activity in vitro with an IC 50 value of 25.6 μ m . Compounds 1 and its acetyl derivative 1a were also tested for their cytotoxicity against the human cervix carcinoma cell line KB-3-1 and still showed moderate activity.

Publicly Available March 11, 2016

A tetranuclear copper (II) complex with pyrazole-3,5-dicarboxylate ligands: synthesis, characterization and electrochemical properties

Selçuk Demir, Hamide Merve Çepni, Małgorzata Hołyńska, Muammer Kavanoz

Page range: 305-310

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Abstract

A tetranuclear copper (II) complex with pyrazole-3,5-dicarboxylate ligands (pdc 3− ), [Me 2 NH 2 ] 4 [Cu 4 (pdc) 4 ], was synthesized using solvothermal and metal oxidation routes and characterized by elemental analysis, infrared, thermogravimetry/differential thermal analysis, and room-temperature magnetic measurements. The structure of the complex was determined by single-crystal X-ray diffraction. It comprises dimethylammonium cations and complex anions containing four Cu 2+ cations. The crystal structure is stabilized by N–H···O hydrogen bonds. In addition, the electrochemical behavior was studied.

Publicly Available March 18, 2016

Synthesis and structure of a cobalt coordination polymer based on 2,8-di(pyridin-4-yl)dibenzothiophene and 4,4-dicarboxydiphenylsulfone

Yan Jiao, Dan-Xia Zhao, Kai-Ping Yang, Xin Liu, Cheng-Yan Huang, Ming-Dao Zhang, Min-Dong Chen

Page range: 311-315

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Abstract

A new coordination polymer {[Co 2 (DPDBT) 2 (DCPS) 2 (H 2 O)](H 2 O)} n ( 1 ) [DPDBT = 2,8-di(pyridin-4-yl)dibenzothiophene, H 2 DCPS = 4,4′-dicarboxydiphenyl sulfone], was synthesized under solvothermal conditions. Complex 1 exhibits a 2D structure with two different kinds of binuclear cobalt cluster units. The UV/Vis spectra of 1 and of the ligands were investigated, indicating that complex 1 is a potential wide gap semiconductor material.

Publicly Available March 18, 2016

ⁿBu₄NI-catalyzed direct amination of benzoxazoles with tertiary amines using TBHP as oxidant under microwave irradiation

Jin-Wei Yuan, Ming Jin, Qiu-Yue Yin, Pu Mao, Ling-Bo Qu

Page range: 317-325

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Abstract

A facile, efficient, and practical method for n Bu 4 NI-catalyzed direct C–H amination of benzoxazoles with tertiary amines has been developed. The system could be performed in the absence of metal catalyst and only requires tert -butyl hydroperoxide as oxidant under microwave irradiation. A variety of substituted benzoxazol-2-amines were synthesized with moderate to good yield.

Publicly Available March 4, 2016

Synthesis, single-crystal structure determination and Raman spectra of the tricyanomelaminates NaA₅[C₆N₉]₂ · 4 H₂O (A = Rb, Cs)

Olaf Reckeweg, Armin Schulz, Francis J. DiSalvo

Page range: 327-332

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Abstract

Transparent colorless crystals of Na A 5 [C 6 N 9 ] 2 · 4 H 2 O ( A = Rb, Cs) were obtained by blending aqueous solutions of Na 3 [C 6 N 9 ] and RbF or CsF, respectively, and subsequent evaporation of the water under ambient conditions. Both compounds crystallize in the space group P 2 1 / m (no. 11) with the cell parameters a = 815.56(16), b = 1637.7(4) and c = 1036.4(3) pm, and β = 110.738(12)° for NaRb 5 [C 6 N 9 ] 2 · 4 H 2 O and a = 843.32(6), b = 1708.47(11) and c = 1052.42(7) pm, and β = 112.034(2)° for NaCs 5 [C 6 N 9 ] 2 · 4 H 2 O, respectively. Raman spectra of the title compounds complement our results.

Publicly Available March 18, 2016

Synthesis of structural analogues of GGT1-DU40, a potent GGTase-1 inhibitor

Muhammad Mansha, Nisar Ullah, Khalid Alhooshani

Page range: 333-344

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Abstract

A series of new substituted pyrazoles 2 – 12 have been synthesized. The synthesized compounds are structural analogues of GGT1-DU40 1 , a highly potent and selective inhibitor of protein geranylgeranyltransferase I (GGTase-I) both in vitro and in vivo. The implications of GGTase-I in oncogenesis have highlighted its potential as a cancer therapeutic target. Accordingly, the development of GGTase-I inhibitors has been a subject of much interest. The synthesis of 2 – 12 stemmed from the acetylation or acylation of N-function of amino acids to produce suitably modified amino acids. Meanwhile, the substituted pyrazole subunit originated from the reaction of ethyl nicotinate with γ -butyrolactone followed by condensation of the resultant β -keto lactone with (3,4-dichlorophenyl)hydrazine. The operations of O-alkylation and thioetherification on the resultant intermediate eventually produced the substituted pyrazole fragment. The amidation of the latter with amino acid derivatives finally rendered 2 – 12 in good to excellent yields.

Note

Publicly Available March 9, 2016

Crystal structure of a dimeric 1-benzothiepin

Dieter Schollmeyer, Dieter Gröschl, Herbert Meier

Page range: 345-347

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Abstract

The crystal structure of the 1-benzothiepin derivative meso - 5 is presented. Compound 5 is the first dimeric 1-benzothiepin system.

About this journal

Objective
Zeitschrift fuer Naturforschung B (ZNB) publishes novel research in all areas of inorganic chemistry, organic chemistry, and analytical chemistry. In particular, the journal focuses on solid state chemistry, coordination chemistry, main group element chemistry, synthetic organic chemistry, natural product chemistry and, to a lesser extent, on analytical chemistry. For more than 65 years Zeitschrift fuer Naturforschung B has been open to contributions from all fields of experimental and theoretical chemistry. Zeitschrift fuer Naturforschung B publishes 12 issues per volume/year. Sometimes double issues occur.

Topics

Solid state chemistry
Coordination chemistry
Main group element chemistry
Organic chemistry
Natural product chemistry

Article formats
Original (full) papers, research notes and preliminary communications, reports on specific research topics of current interest (reviews)

> Information on submission process

Volume 71 Issue 4

Issue of Zeitschrift für Naturforschung B

Frontmatter

In this Issue

Ferromagnetism in Fe3−x−yNixGeTe2

Abstract

A novel potentiometric sensor based on urease/ bovine serum albumin-poly(3,4-ethylenedioxythiophene)/Pt for urea detection

Abstract

Two new glycosidal metabolites of endophytic fungus Penicillium sp. (NO.4) from Tapiscia sinensis

Abstract

New bioactive metabolites from Penicillium purpurogenum MM

Abstract

Long-chain alkyl-substituted gentisic acid and benzoquinone derivatives from the root of Micronychia tsiramiramy (Anacardiaceae)

Abstract

A tetranuclear copper (II) complex with pyrazole-3,5-dicarboxylate ligands: synthesis, characterization and electrochemical properties

Abstract

Synthesis and structure of a cobalt coordination polymer based on 2,8-di(pyridin-4-yl)dibenzothiophene and 4,4-dicarboxydiphenylsulfone

Abstract

nBu4NI-catalyzed direct amination of benzoxazoles with tertiary amines using TBHP as oxidant under microwave irradiation

Abstract

Synthesis, single-crystal structure determination and Raman spectra of the tricyanomelaminates NaA5[C6N9]2 · 4 H2O (A = Rb, Cs)

Abstract

Synthesis of structural analogues of GGT1-DU40, a potent GGTase-1 inhibitor

Abstract

Crystal structure of a dimeric 1-benzothiepin

Abstract

Ferromagnetism in Fe_3−x−yNi_xGeTe₂

ⁿBu₄NI-catalyzed direct amination of benzoxazoles with tertiary amines using TBHP as oxidant under microwave irradiation

Synthesis, single-crystal structure determination and Raman spectra of the tricyanomelaminates NaA₅[C₆N₉]₂ · 4 H₂O (A = Rb, Cs)