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  • Author: Gayane Tokmajyan x
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New derivatives of substituted saturated γ-lactones were synthesized from 2-(2,2-dimethyl-5-oxotetrahydrofuran-3-yl)acetyl chloride. All new compounds were characterized by NMR and IR and elemental analysis.


2,5-Dihydro-2-oxofuran-3-carboxamides were synthesized by a one-pot two-step reaction catalyzed by sodium methoxide. Readily available tertiary α-hydroxyketones were condensed with substituted cyanoacetamides to give 2-imino-2,5-dihydrofuran-3-carboxamides that, without isolation, were hydrolized to the title products.