Acute pancreatitis in pregnancy (APIP) is rare and the reasons for APIP are biliary disease and congenital or acquired hypertriglyceridemia, which could occur during any trimester but more than 50% cases happened during the third trimester. In this report, one case of a young pregnant woman, a HBV carrier in her 37th week + 5 d of gestation, was admitted to Emergency Department due to acute abdominal pain, vomiting and diarrhea. The patient was in antiretroviral treatment with telbivudine from 28 weeks of gestation to prevent motherto- child transmission of HBV. Laboratory tests demonstrated hypertriglyceridemia, abdominal computed tomography scan revealed peripancreatic edema. Hyperlipidemic pancreatitits was primary diagnosed and the patient was admitted to the intensive care unit. Considering the possible role in the pathogenesis of pancreatitis, telbivudine was interrupted after birth giving. After supportive treatment, her condition gradually improved. Since it is the first description of APIP during treatment with telbivudine, the association between pregnancy, hyperlipidemia, telbivudine and acute pancreatitis has been well investigated.
Background: Inborn errors of metabolism (IEM) have been detected worldwide using gas chromatography mass spectrometry (GC-MS) since the 1980s, but few related reports exist on the incidence, spectrum, and clinical presentation features of IEM in southern China.
Method: From January 2009 to March 2012, 16,075 urine samples were collected from patients who were highly suspected of having IEM in Guangzhou Women and Children’s Medical Center. The specimens were evaluated using GC-MS.
Results: We diagnosed 303 cases of IEM by urine GC-MS analysis, including 197 cases with amino acid disorders, 86 cases with organic acidurias (OAs), 10 cases with fatty acid oxidative (FAO) disorders, and 10 cases with peroxisomal disorders. Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) was the most common (153 cases), followed by methylmalonic aciduria (48 cases), urea cycle disorders (21 cases), phenylketonuria (20 cases), propionic aciduria (11 cases), X-linked adrenoleukodystrophy (10 cases), multiple carboxylase deficiency (8 cases), glutaric aciduria type I (7 cases), isovaleric aciduria (6 cases), glutaric aciduria type II (4 cases), short-chain acyl-CoA dehydrogenase deficiency (4 cases), 3-hydroxy-3-methylglutaric aciduria (3 cases), maple syrup urine disease (2 cases), very long-chain acyl-CoA dehydrogenase deficiency (1 case), malonic aciduria (1 case), mevalonic aciduria (1 case), Canavan disease (1 case), lysine protein intolerance (1 case), and medium-chain acyl-CoA dehydrogenase deficiency (1 case). The clinical and laboratory features of IEM are neurologic signs, jaundice, metabolic acidosis, ketotic hypoglycemia, and hyperammonemia.
Conclusion: In our study, GC-MS provided a diagnostic clue to OAs, amino acid disorders, FAO, and peroxisomal disorders. Urease pretreatment is useful for the diagnosis of NICCD. In southern China, the majority of IEM were amino acid disorders and organic acid disorders. FAO disorders were relatively rare, which we need to investigate further.
This paper is concerned about the impulsive control of a class of novel nonlinear fractional-order financial system with time-delay. Considering the variation of every states in the fractional-order financial system in the real world has certain delay for various reasons, thus we add corresponding delay on every state variable. Different from the traditional method of stability judgment, we choose two dimensions of time and space to analyze, which makes the process more accurate. In addition, the sufficient condition of the stability criterion for the fractional-order financial system based on impulsive control is derived. Moreover, the impulsive control can not only make the fractional-order financial system stable in different time delay but also in the different fractional operator. Consequently, the impulsive control has generality, universality and strong applicability. In the end, some numerical simulation examples are provided to verify the effectiveness and the benefit of the proposed method.
Graphene oxide (GO) was prepared by the Hummers method and was grafted by an amino-terminated vinyl polydimethylsiloxane (AP). The AP-modified GO (GO-AP) was incorporated in poly(methylmethacrylate) (PMMA) to prepare nanocomposites. Raman microscopy, Fourier transformed infrared spectroscopy, X-ray diffraction, X-ray photoelectron spectroscopy, and thermogravimetric analysis were used to characterize the particles. The mechanical properties, thermal stability, thermal conductivity, and dispersing status of the PMMA-based nanocomposites were also investigated. The results indicated that AP was grafted on the surface of GO via the amidation reaction, and the quantity of the grafted AP was approximately 20 wt% that of GO-AP. With the addition of GO-AP, the three-point bending strength of GO-AP/PMMA increased to approximately 58 MPa, and the dispersion of the particles was also enhanced. GO wrapped by AP could not form thermal conducting networks at the percolation thresholds. The increasing amount of AP prevented the formation of thermal conduction network and decreased the thermal conductivity of the composites. The thermal stability of the composites was affected by three main reasons, and the total effect of the three reasons on thermal stability illustrated a negative trend.
In the past decades narrow band was used as the excitation signal to measure the reverberation time and sound absorption coefficient in reverberation room. In this paper narrow band as excitation signal to measure the sound absorption coefficient of the polyester fiber and perforated aluminum plate and is compared with the results obtained by using white noise. The test time of excitation signal using white noise than which using narrow band to save 102 minutes in the same experimental conditions. The accuracy of the measurement results of the two methods is discussed. This paper has a certain reference value for improving the efficiency of the measurement of sound absorption in reverberation room.