A new 3D fourfold interpenetrated metal-organic framework, [Co(L)2(SO4)]・H2O (1), has been synthesized by the solvothermal reaction of L with CoSO4・6H2O (L = 1,4-bis(imidazolyl)benzene). Compound 1 crystallizes in the monoclinic space group P21/n, with the cell parameters: a = 9.943(2), b = 21.7104(15), c = 13.2658(18) Å , β = 97.638(3)◦, V = 2838.2(8) Å3, R1 = 0.0566 and wR2 = 0.1035. It represents a novel dia net, in which the cobalt atoms are alternately bridged by the imidazolyl N atoms of the ligands L into a three-dimensional network. Compound 1 displays antiferromagnetic interactions. From 2 to 300 K, χm −1 it obeys the Curie-Weiss law with C =2.68 emu K mol−1 and Θ = −2.59 K
Structural modifications were performed on isoalantolactone in an effort to find compounds with potential anticancer activity. Seven previously unknown adducts of active methylene compounds with isoalantolactone were synthesized by the Michael reaction. Moreover, four derivatives of aryl-substituted isoalantolactone were prepared by the Heck reaction. All synthetic products were evaluated for toxic activities against three different hepatoma cell lines, Bel-7402, SMMC-7721, and Hep G2. Products prepared through the Heck reaction and 3a,b show potential antiproliferative activity against the Hep G2 cell.
In the present work, the density, ρ, refractive index, nD, and dynamic viscosity, η, for four binary solutions containing ionic liquids [Cnmim]X (Cnmim = 1-alkyl-3-methylimidazolium; n = 6, 8; X = Cl, Br) and ethylene glycol (EG) were investigated at temperatures of 288.15-333.15 K and at ambient pressure. In addition, the excess molar volume, VEm, was calculated and correlated using the Redlich-Kister polynomial equation. The temperature effect on the density of the binary systems studied was expressed by a linear two-parameter equation. The variation in density, refractive index, and viscosity with the composition was described by polynomial equations. The influence of carbon chain-length and the anion of the ionic liquids, and the influence of the temperature on the physicochemical properties of the binary systems can be explained by comparison of the experimental results.
Stimuli responsive helical polymers have attracted wide attention and many polymers responsive to the external stimuli have been synthesized. But, only a few examples have been reported regarding the redox-induced helicity inversion helical polymers. The polyisocyanide including thioether pendant (poly-MBTIP) was synthesized by polymerization of methyl (R)-3-(benzylthio)-2-isocyanopropanoate (MBTIP) monomer using NiCl2·6H2O as catalytic agent in dry DCM. The chiroptical and oxidation properties of the poly-MBTIP are investigated. The poly-MBTIPs exhibit intense specific optical rotations and Cotton effects compared to the monomer, strongly suggesting a helical conformation of the polymer backbone. Additionally, the thioether pendant of poly-MBTIP backbone was oxidized to sulfoxide group by H2O2. Interestingly, the specific optical rotations and Cotton effects of poly-MBTIP oxidized are reversed, probably suggesting a helical conformation inversion.