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  • Author: S.A. Furman, x
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Abstract

The response of a quadrupolar spin system in zero applied magnetic field to a long rf pulse, for both single crystal and polycrystalline samples possessing broad Lorentzian-shaped resonance lines has been studied. The dependencies of magnetization on frequency offset, linewidth and power are investigated both theoretically and experimentally. The problem of the effective field direction in both single crystal and polycrystalline samples is also discussed. For a polycrystalline cuprous oxide (Cu2O) sample it is observed that the magnetization after a long pulse in on-resonance condition does not become zero for time t ≫ T2 , in agreement with theoretical results. It has also been shown that the magnetization increases with increase in the width of the resonance line as well as with the decrease in the excitation power.

Abstract

The objective of this study was to perform a comprehensive evaluation of major indices of pain syndrome in patients with mandibular fractures accompanied by damage of inferior alveolar nerve using conventional therapeutic regimen supplemented by the administration of drug product Nucleo CMP Forte. Operative and postoperative treatment of 50 patients with angular fractures of the mandible, accompanied by clinical manifestations of inferior alveolar nerve damage, was performed. The severity of pain syndrome and neuropathy symptoms was evaluated using the LANSS pain scale, DN4 questionnaire, the Visual Analogue Scale (VAS) and Neuropathy Total Symptom Scores (NTSS-9). Decrease of pain syndrome was revealed in both groups but with different dynamic pattern. In the treatment group pain syndrome manifestations and neuropathy symptoms decreased quicker than in the comparison group. As LANSS, DN4, VAS and NTSS-9 scales characterize pain syndrome from various perspectives, the results were different but similar tendency was shown. At the beginning of the study LANSS scale indices were nearly identical in both groups, while on the 7th and 14th day they were 1.35 and 2.03 times lower, respectively, in the treatment group compared to the control group. On the first day NTSS-9 scale values did not practically differ in between the studied patients, being somewhat higher in the treatment group. On the 7th and 14th day the values increased 1.24 and 3.82 times, in the treatment group and in the group of comparison, respectively. Thus, the patients in the treatment group showed significantly greater pain relief than those in the comparison group. The analysis of dynamic pattern of complaints as well as the objective findings in angular fractures of the mandible, accompanied by the damage of inferior alveolar nerve, demonstrated that the administration of drug product Nucleo CMP Forte led to a more pronounced improvement of pain syndrome in the course of treatment. Because of the fact that neuropathic pain can develop in orthodontic treatment, as well as when partial and complete removable dentures are used, the administration of drug product Nucleo CMP Forte is warranted in combined therapy of both mandibular fractures followed by the clinical manifestations of inferior alveolar nerve damage, and neuropathic pain management in orthodontics and orthopedic stomatology.

We present a detailed theoretical and experimental NQR multiple-pulse spin-locking study of spin-lattice relaxation and spin diffusion processes in the presence of paramagnetic impurities in solids. The obtained diffusion equation was obtained allows to find the time dependence of the magnetization in the effective field. The spin lattice relaxation times were calculated, both for direct and diffusion regimes, as functions of the correlation time and multiple-pulse parameters. Measurements of relaxation times in rotating frame allow to determine the diffusion coefficient and the radius of the diffusion barrier in γ-irradiated polycrystalline samples of NaCIO3.