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[1] KDOQI; National Kidney Foundation. KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Anaemia in Chronic Kidney Disease. Am J Kidney Dis. 2006;47(5 Suppl 3):S11–145 [2] Felker GM, Adams KF Jr, Gattis WA, O’Connor CM. Anaemia as a risk factor and therapeutic target in heart failure. J Am Coll Cardiol. 2004;44:959–966 [3] Yi-Da Tang, Katz SD. Anaemia in chronic heart failure. Circulation 2006;113:2454–2461 [4] Go AS, Yang J, Ackerson LM

Introduction In the recent years, our studies have demonstrated that T cells were hyperfunctional in patients with acquired aplastic anemia (AA). The excessive apoptosis of hematopoietic stem cells caused by cytotoxic T cells and/or lymphokines is the main pathogenesis of acquired AA. Up to now, acquired AA has been recognized by some scholars as an autoimmune disease with bone marrow (BM) as target organ attacked by the activated T lymphocytes. Therefore, immunosuppressive therapy (IST) has become the best choice for the treatment of acquired AA if there is no

Int J Disabil Hum Dev 2010;9(2-3):217–223 2010 by Walter de Gruyter • Berlin • New York. DOI 10.1515/IJDHD.2010.030 2010/030 Article in press - uncorrected proof Adult patients with childhood anemias Vlad Calin Radulescu* and Jeffrey A. Moscow Pediatric Hematology Oncology, Kentucky Clinic, University of Kentucky, Lexington, KY, USA Abstract The chronic, lifelong anemias, diagnosed in childhood and extending into adult life are due to genetic defects that either affect the production and maturation of the red blood cells or that shorten the lifespan of the red

-PÉREZ E, MARTÍNEZ-BÁEZ AZ. Iron status and dietary intakes of iron in normal-weight and obese young Mexican women . Nutr Hosp. 2015; 31(6):2412-8. 17. KORDAS K, FONSECA CENTENO ZY, PACHÓN H, JIMENEZ SOTO AZ. Being overweight or obese is associated with lower prevalence of anemia among Colombian women of reproductive age . J Nutr. 2013;143(2):175-81. 18. CROWLEY LV, OLSON RW. Megaloblastic anemia after gastric bypass for obesity . Am J Gastroenterol. 1983; 78 : 406-10.

;9:1805-1811. 5. Tischkowitz, MD, Hodgson SV. Fanconi anaemia. Journal of Medical Genetics. 2003;40:1-10. 6. Joenje H, Levitus M, Waisfisz Q, et al. Complementation analysis in Fanconi anemia: assignment of the reference FA-H patient to group A. Am J Hum Genet. 2000;67:759-762. 7. Liu JM, Kim S, Read EJ, et al. Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC). Hum Gene Ther. 1999;10:2337-2346. 8. Alter BP, Greene MH, Velazquez I, Rosenberg PS. Cancer in Fanconi anemia. Blood. 2003;101:2072. 9. D’Andrea A. Susceptibility

;48:1066–76. 10.1093/clinchem/48.7.1066 24. Punnonen K, Irjala K, Rajamaki A. Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 1997;89:1052–7. 10.1182/blood.V89.3.1052 25. Weiss G, Goodnough LT. Anemia of chronic disease. New Engl J Med 2005;352:1011–23. 10.1056/NEJMra041809 26. Cartwright GE, Lee GR. The anaemia of chronic disorders. Br J Haematol 1971;21:147–52. 10.1111/j.1365-2141.1971.tb03424.x 4934605 27. Weiss G. Iron metabolism in the anemia of chronic disease. Biochim Bioph acta 2009;1790:682–93. 10.1016/j.bbagen.2008

-He) provides both an indirect measure of functional iron available for new RBC production over the previous 3–4 days, and is an early measure of the 1218 Guidi and Santonastaso: Anemias of chronic conditions Article in press - uncorrected proof Table 2 Criteria for diagnosis of anaemia. Age Hb, g/L Hb children (6 months–6 years) 110 Hb children (6–14 years) 120 Female non-pregnant Adult 120 Female pregnant Adult 110 Male Adult 130 Report of a WHO Scientific Group. WHO Tech Rep Ser 1968; 405:1–40 (10). Table 1 Standardization of hematological parameters. Parameters CVw

Introduction Anaemia is a common nutritional deficiency disorder and global public health problem in both developing and developed countries with major socio-economic consequences. Anemia has attained epidemic proportions worldwide with about two billion patients estimated to suffer from anaemia worldwide and it is reported to account for three quarters of one million deaths a year in Africa and South-East Asia [ 1 ]. Anaemia can be defined as the reduction in the number of circulating erythrocytes or haemoglobin concentration (Hb) or both below the normal values