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Effects of Antifungal Compounds on Conidial Germination and on the Induction of Appressorium Formation of Magnaporthe grisecfi Frank Eilbert3, Eckhard Thinesb and Heidrun Anke3 * a Departm ent for Biotechnology, University of Kaiserslautern, Paul-Ehrlich-Str. 23, D-67663 Kaiserslautern, Germany. Fax: +49 631/205-2999. E-mail: anke@rhrk.uni-kl.de b School of Biological Sciences, University of E xeter, Washington Singer Laboratories, Perry Road, Exeter E X 4 4Q L , United Kingdom * Author for correspondence and reprint requests Z. Naturforsch. 54c, 9 0 3 -9 0 8

Antifungal Compounds Induced in the Dual Culture with Phytolacca americana Callus and Botrytis fabae Akio Kobayashi, Kohtatsu Hagihara, Shin-ichiro Kajiyama, Hiroshi Kanzaki and Kazuyoshi Kawazu Department of Agricultural Science. Faculty of Agriculture, Okayama University, Okayama 700. Japan Z. Naturforsch. 50c, 398-402 (1995); received January 3. 1995 Dual Culture, Antifungal Compounds. Phytolacca americana. Botrytis fabae. Phytolaccoside B In order to investigate new metabolites which are only induced in a plant callus infected by a pathogenic fungus, dual

487S.T. Chang et al.: Antifungal Compounds Isolated from Taiwania Heartwood Introduction Taiwania (Taiwania cryptomerioides Hayata) is an econom- ically important tree species indigenous to Taiwan. The heartwood of Taiwania is yellowish red with distinguished purplish pink streaks. With regard to the decay resistance, Taiwania is classified into the excellent durability species in Taiwan. It is well known that extractives influence the dura- bility of wood. There were many kinds of extractives iso- lated and identified from Taiwania, including eleven lig- nans

Pure &App/. Chern., Vol. 66, Nos lO/ll, pp. 2231-2234, 1994. Printed in Great Britain. Q 1994 IUPAC Search for new antifungal compounds from higher plants K. Hostettmann* and A. Marston Institut de Pharmacognosie et Phytochimie, Universite de Lausanne, CH- 101 5 Lausanne-Dorigny, Switzerland. Abstract: The increasing occumnce of opportunistic systemic mycoses associated with the use of immunosuppressive drugs and AIDS has led to new efforts in the search for novel antifungal compounds. At the same time, there is continuing interest in the discovery of

Elicitor-Active Oligosaccharides from Algal Laminaran Stimulate the Production of Antifungal Compounds in Alfalfa A k io K o b a y a sh i, A k ih ir o T a i, H ir o sh i K a n z a k i, a n d K a z u y o sh i K a w a z u D epartm ent o f Agricultural Science, O kayam a U niversity, O kayam a 700, Japan Z. Naturforsch. 48 c, 5 7 5 -5 7 9 (1993); received M arch 5/M ay 12 ,1993 Elicitor, A lfa lfa , Phytoalexin A ccum ulation , Natural P olysaccharide, Pyridylam ination Natural polysaccharides w ere exam ined for their activity as elicitors o f

Xylaramide, a New Antifungal Compound, and Other Secondary Metabolites from Xylaria longipes G udrun Schneider', H eidrun A nke3 and Olov Sternerb a LB Biotechnologie, U niversität K aiserslautern. Paul Ehrlich-Straße 23, D-67663 K aiserslautern. B undesrepublik D eutschland h Division of O rganic Chem istry 2. U niversity of Lund. P. O. B. 124. S-221 00 Lund. Sweden Z. N aturforsch. 51c, 802-806 (1996); received May 30/August 8. 1996 Xylaramide. 2.5-B is(hydroxym ethyl)furan. Tyrosol. Xylaria longipes, Antifungal Xylaram ide (1), possessing potent antifungal

Abstract

Antifungal activity of organic compounds (aromatic, salicylic derivatives, cinnamyl derivatives etc) on Fusarium Rosium (14 compounds) and Aspergillus niger (17 compounds) was studied and QSAR models were developed relating molecular descriptors with the observed activity. Back propagation Neural Network models and single and multiple regression models were tested for predicting the observed activity. The data fit as well as the predictive capability of the neural network models were satisfactory (R2 = 0.84, q2 = 0.73 for Fusarium Rosium and R2 = 0.75, q2 = 0.62 for Aspergillus niger). The descriptors used in the network for the former were X4 (connectivity) and Jhetv (topological); and TIC1 (information) and SPI (topological) for the latter fungus. Antifungal activities of these organic compounds were generally lower against the latter than with the former fungus.

1183 Pure Appl. Chem., Vol. 77, No. 7, pp. 1183–1189, 2005. DOI: 10.1351/pac200577071183 © 2005 IUPAC Application of the carbene cyclization–cycloaddition cascade in total synthesis* Pauline Chiu Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China Abstract: The title reaction is a key transformation that has been applied to the synthetic stud- ies of the antitumor and antifungal compounds, the pseudolaric acids

A Survey of Phytoalexin Induction in Leaves of the Rosaceae by Copper Ions Tetsuo Kokubun and Jeffrey B. Harborne Department of Botany, University of Reading, Whiteknights, Reading, RG6 2 AS, U.K. Z. Naturforsch. 49c, 628-634 (1994); received April 28/May 26, 1994 Phytoalexins. Constitutive Fungitoxins, Hydroquinone, Aucuparin The leaves of 130 species of Rosaceae were surveyed for phytoalexin induction. Both biotic and abiotic induction was examined and antifungal compounds were detected in 47 species. However, these compounds appeared to be constitutive