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Nowadays bioactive glasses represent one of the most successful bioceramics used for bone tissue restorations. In this work, three types of silica sands (White, Yellow and Gray Sands) and calcite from Cuban natural deposits were employed to synthesize glasses from the system SiO2–CaO–Na2O. The ions released from glasses were evaluated through in vitro tests in Tris-HCl and in simulated body fluids. All sands had purity around 99.2% of SiO2 and contained traces (ppm) of Zr, Cr, Ba, Ce and Sr ions, while calcite raw material had traces of Sr, Cr, Zr, Ce and Zn. All glasses induced a pH change in Tris-HCl from 7.4 to 9 after 24 h; they had similar ion-release behavior in the in vitro solutions tested and showed a significant bioactive performance after 5 h. This work illustrates the potentialities of the use of natural resources to develop medical products when recognized trademark materials are not available.
properties, by taking advantage of the inherent high surface area/volume ratio of nanoparticles . This paper gives an overview of the application of inorganic nanoparticles in biomedical fields, with a focus on hydroxyapatite and bioactive glass nanoparticles for bone tissue engineering. First, a brief overview of the chemical structure and some common methods used to produce synthetic hydroxyapatite and bioactiveglasses has been presented (in their respective sections). The main body of the paper covers the physical and biological properties of these biomaterials, as
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