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(TK1) in the peripheral blood of malignant carcinoma patients were significantly increased, suggesting their potential as serological markers for cancer diagnosis [ 9 , 10 , 11 , 12 ]. In this study, the expression levels of serum miR-183 and TK1 in 46 colorectal cancer patients and 46 healthy controls are measured, and the feasibility and clinical value of diagnostic biomarkers for colorectal cancer are analyzed. 2 Materials and methods 2.1 Patients and controls inclusion Colorectal cancer patients who visited our hospital for treatment from February 2015 to Jan

1 Introduction In the past two decades, several serum biomarkers for epithelial ovarian cancer diagnosis have been studied, such as Ca125, Ca199, CEA, HE4 and et al [ 1 ]. Ca125 is also known as mucin 16 or MUC16, a protein that in humans is encoded by the MUC16 gene. It was found serum Ca125 had been elevated in patients with specific types of cancers, which could be a potential biomarker [ 2 ]. Several studies have discussed the serum Ca125 level in ovarian cancer patients and found about 80% of advanced patients had elevated levels of Ca125 in their blood [ 3

.1993;118:793-803. 5. Tenke P, Horti J, Balint P, Kovacs B. Prostate cancer screening. In: J. Ramon, L. J. Denis (eds). Prostate cancer. Recent results in cancer research. Springer, Berlin, Heidelberg; 2007. p. 175. 6. 7. Welch HG, Albertsen PC. Prostate cancer diagnosis and treatment after the introduction of prostate-specific antigen screening: 1986-2005. JNCI. 2009;101;19(7):1325-9. 8. Kundra V, Silverman PM, Matin SF, Choi H. Imaging in oncology from the university of Texas M. D. Anderson Cancer Center: diagnosis, staging

random-effects model is used to obtain the general values of sensitivity and specificity. Overall sensitivity value was found as 0.82 (95% confidence interval: 0.78–0.86); overall specificity value was found as 0.84 (95% confidence interval: 0.79–0.88). Area under the summary ROC curve was obtained as 0.89. Discussion and conclusion Fiber optic spectroscopy techniques have the potential to become an important biomedical optical tool for cancer diagnosis. Recently, significant improvement has been made in the discriminating abilities of these techniques between normal

. Therefore, early diagnosis is important for improving the survival of patients with colorectal cancer. Serum biomarkers for colorectal cancer screening or diagnosis is generally used clinically such as CEA, CA199 and et al [ 3 , 4 ]. Cytokertation 20 (CK20) protein is widely used as a serum biomarker for cancer screening or diagnosis. However, the efficacy of using the serum level of CK20mRNA as a biomarker for colorectal cancer diagnosis is not clear according to the previously published studies with small sample sizes. Therefore, we performed this meta-analysis to

with universal health care, the response to COVID-19 epidemic was swift and included changes in the functioning of the health care system that potentially affected cancer diagnosis and management. An overview of the COVID-19 epidemic in Slovenia The first confirmed COVID-19 patient in Slovenia was registered on the 4 th of March 2020. The first cases were imported, though soon, secondary, tertiary and quaternary transmissions of the novel virus were detected and on the 12 th of March, the Health Minister following the advice of the National Institute of Public

DOI 10.1515/revac-2012-0019      Rev Anal Chem 2013; 32(1): 55–76 Pedro H.B. Aoki , Leonardo N. Furini , Priscila Alessio , Alvaro E. Aliaga and Carlos J.L. Constantino * Surface-enhanced Raman scattering (SERS) applied to cancer diagnosis and detection of pesticides, explosives, and drugs Abstract: The inelastic scattering of light, Raman scatter- ing, presents a very low cross section. However, the signal can be amplified by several orders of magnitude, lead- ing to the so-called surface-enhanced Raman scattering (SERS) phenomenon. Basically

BIOCHEMICAL MARKERS IN PANCREATIC CANCER DIAGNOSIS A. Burlina, M. Plebani Cattedra di Chimica e Microscopia Clinica, Laboratorio Centrale Università di Padova, 35128 Padova, Italy C. Fabris, D. Basso, G. Del Favero and R. Naccarato Cattedra di Malattie dell'Apparato Digerente Università di Padova, 35128 Padova, Italy- Introduction Because of the inability in most cases to make an early diagnosis, pancreatic cancer has a poor prognosis with an average survival of four months. Furthermore its incidence and mortality have been in- creasing rapidly in many

Clin Chem Lab Med 2011;49(3):443–445 2011 by Walter de Gruyter • Berlin • New York. DOI 10.1515/CCLM.2011.073 2011/002 Article in press - uncorrected proof Editorial ROMA or death: advances in epithelial ovarian cancer diagnosis Mario Plebani and Bohuslav Melichar Epithelial ovarian cancer (EOC) is the fourth most common cause of cancer mortality in women in the Western world, and the leading cause of death from gynecological malig- nancy. The high death rate from EOC is mostly attributable to its late detection at an advanced stage and the high ten- dency for

In parallel to the continual increase in cancer diagnosis all over the world, the number of studies on tumorigenesis is constantly rising. However, there are still no curative treatment options available for patients, particularly for those suffering from advanced metastatic malignancies, and many aspects related to carcinogenesis process have remained mysterious even in the 21 st century. Based on the global cancer statistics, one in two men and one in three women will be diagnosed with some type of invasive cancer during their lifetime [ 1 , 2 , 3