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-based, cross-sectional study in Banbury (Oxfordshire, UK). Clin Endocrinol (Oxf) ;72(3), 377-82. doi: 10.1111/j.1365-2265.2009.03667.x. 4. Schlechte, J.A. (2007). Long-term management of prolactinomas. J Clin Endocrinol Meta. 92(8), 2861-5. 5. Kars, M., Dekker,s O.M., Pereira, A.M. & Romijn, J.A. (2010). Update in prolactinomas. Neth J Med. 68(3), 104-12. 6. Karunakaran, S., Page, R.C. & Wass, J.A. (2001). The effect of the menopause on prolactin levels in patients with hyperprolactinaemia. Clin Endocrinol (Oxf) .54(3),295-300. 7. Naliato, E.C., Violante, A.H., Caldas, D

Clin Chem Lab Med 2010;48(2):205–208 2010 by Walter de Gruyter • Berlin • New York. DOI 10.1515/CCLM.2010.038 2010/383 Article in press - uncorrected proof Short Communication The Beckman DxI 800 prolactin assay demonstrates superior specificity for monomeric prolactin Brendan Byrne*, Paula O’Shea, Patricia Barrett and William Tormey Department of Chemical Pathology, Beaumont Hospital, Dublin, Ireland Abstract Background: Commercially available prolactin immunoas- says detect macroprolactin to variable degrees. Best practice requires laboratories to assess the

References Andrews Z.B., Kokay I.C., Grattan D.R. (2002). Disociation of prolactin secretion from tuberoinfundibular dopamine activity in late pregnant rats. Endocrinology, 142: 2179-2724.Arbogast L.A., Voogt J.L. (1996). The resposiveness of tuberoinfundibular dopaminergic neurons to prolactin feedback is diminished between early lactation and midlactation in the rat. Endocrinology, 1: 137. Arihara Z., Sakurai K., Yamashita R., Niitsuma S., Ueno T., Yamamura N., Ya - mada S., Inoshita N., Takahashi K. (2014). Bromocriptine,adopamine agonist, increases growth

R eferences 1. Ziyadeh FN, Sharma K . Overview: combating diabetic nephropathy. J Am Soc Nephrol 14(5): 1355-7, 2003. 2. Alrefai H, Allababidi H, Levy S, Levy J. The endocrine system in diabetes mellitus. Endocrine 18: 105-19, 2002. 3. Freeman ME, Kanyicska B, Lerant A, Nagy G . Prolactin: structure, function, and regulation of secretion. Physiol Rev 80: 1523-631, 2000. 4. Lau C, Sullivan MK, Hazelwood RL . Effects of diabetes mellitus on lactation in the rat. Proc Soc Exp Biol Med 204: 81-89, 1993. 5. Ikawa H, Irahara M, Matsuzaki T, Saito S, Sano T

. 1: 73–83. [4] Bentley P.J. 2002. The Amphibia; Endocrines and Osmoregulation. A Comparative Account in Vertebrates, 2nd Ed., Vol. 1 (Chapter 6), pp. 155–186. In: Bradshaw S.D., Burggren W., Heller H.C., Ishii S., Langer H., Neuweiler G. & Randall D.J. (eds), Zoophysiology, Vol. 39, Springer-Verlag, Berlin, Heidelberg [5] Bole-Feysot C., Goffin V., Edery M., Binart N. & Kelly P.A. 1998. Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr. Rev. 19: 225–268. DOI 10.1210/er.19

, Smith TP, McKenna T. Clinical Relevance of Macroprolactin. Clin Endocrinol 2005; 62: 643-63. Beltran L, Fahie-Wilson MN, McKenna TJ, Kavanagh L, Smith TP. Serum Total Prolactin and Monomeric Prolactin Reference Intervals Determined by Precipitation with Polyethylene Glycol: Evaluation and Validation on Common ImmunoAssay Platforms. Clin Chem 2008; 54: 1673-81. Smith TP, Fahie-Wilson MN. Reporting of Post-PEG Prolactin Concentrations: Time to Change. Clin Chem 2010; 56: 484-5. Smith TP, Suliman AM, Fahie-Wilson MN, McKenna TJ. Gross Variability in the Detection of

Introduction Prolactin (PRL), which consists of 199 amino acid residues, is a kind of peptide hormone secreted by pituitary lactating cells. It is predominantly present as a 23-kDa non-glycosylated monomer [ 1 ]. In 1970, human PRL was isolated from the human pituitary gland for the first time, and PRL was then detected by radioimmunoassay [ 2 ]. As a significant member of the hypothalamus-pituitary-gonadal axis, PRL is regulated mainly by the hypothalamic

Clin Chem Lab Med 2007;45(4):541–545 2007 by Walter de Gruyter • Berlin • New York. DOI 10.1515/CCLM.2007.086 2006/298 Article in press - uncorrected proof Reference intervals for follicle-stimulating hormone, luteinizing hormone and prolactin in children and young adults on the bioMérieux Mini-Vidas system Thu Koskas, Karamo Souaré, Tarik Ouahabi, Dominique Porquet and Didier Chevenne* Service de Biochimie-Hormonologie, Hôpital Robert Debré, AP-HP, Paris, France Abstract We measured serum follicle-stimulating hormone (FSH), luteinizing hormone (LH) and

References Auchtung T.L., Rius A.G., Kendall P.E., McFadden T.B., Dahl G.E. (2005). Effects of photoperiod during the dry period on prolactin, prolactin receptor and milk production of dairy cows. J. Dairy Sci. 88: 121-127. Banks A.S., Davis S.M., Bates S.H., Myers M.G. Jr. (2000). Activation of downstream signals by the long form of the leptin receptor. J. Biol. Chem. 275: 14563-14572. Baratta M., Grolli S., Tamanini C. (2003). Effect of leptin in proliferating and differentiated HC11 mouse mammary cells. Regul. Pept. 113: 101-107. Bole-Feysot C., Goffin V

methohexitone-alfentanil or propofol-alfentanil: clinical aspects and hemodynamic, endocrine and metabolic effects. Anaesthesist 1994, 43: 594–604 http://dx.doi.org/10.1007/s001010050098 [16] Scarborough D.E., Cytokine modulation of pituitary hormone secretion, Ann. N.Y. Acad. Sci., 1990, 594: 169–187 http://dx.doi.org/10.1111/j.1749-6632.1990.tb40477.x [17] Clevenger C.V., Russel D.H., Appasamy P.M., Prystowsky M.D., Regulation of interleukin2-driven T-Lymphocyte proliferation by prolactin, Proc. Natl. Acad. Sci. USA, 1990, 87: 6460–6464 http://dx.doi.org/10.1073/pnas.87