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Phalloidin-Induced Proliferation of Actin Filaments within Rat Hepatocytes Visualisation by Electron Microscopy and Immunofluorescence B. Agostini *, V. M. Govindan **, W. Hofmann ***, and Th. Wieland ** Abteilungen Physiologie * und Naturstoffchemie ** am Max-Planck-Institut für medizinische Forschung, Heidelberg, und Pathologisches Institut der Universität ***, Heidelberg (Z. Naturforsch. 30 c, 793 — 795 [1975]; received July 17, 1975) Phalloidin, Actin, Hepatocytes, Anti-Actomyosin Antibodies, Immunofluorescence Confirming our previous ultrastructural and

Biol. Chem. Hoppe-Seyler Vol. 372, pp. 489-493, July 1991 Polyamines in Rat Hepatocyte Cultures Sebastiane COLOMBATTO and Maria Angelica GRILLO Sezione di Biochimica del Dipartimento di Medicina e Oncologia Sperimentale, Universita' di Torino, Torino, Italy (Received 10 April 1991) Summary: In rat hepatocytes cultured for 120 h polyamine content was markedly modified. Putres- cine concentration reached a maximum at 48 h, sper- midine increased for 48 h and then remained con- stant, spermine after a decrease returned to its initial values. Total polyamine amount

–215. http://dx.doi.org/10.1097/MCC.0b013e3282f70057 [4] Elaut, G., Henkens, T., Papeleu, P., Snykers, S., Vinken, M., Vanhaecke, T. and Rogiers, V. Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. Curr. Drug Metab. 7 (2006) 629–660. http://dx.doi.org/10.2174/138920006778017759 [5] Kaihara, S., Kim, S., Kim, B.S., Mooney, D.J., Tanaka, K. and Vacanti, J.P. Survival and function of rat hepatocytes cocultured with nonparenchymal cells or sinusoidal endothelial cells on biodegradable

rat. Drug Metab Dispos 2000;28:348-53. Carvalho F, Remião F, Amado F, Domingues P, Correia AJ, Bastos ML. D-Amphetamine interaction with glutathione in freshly isolated rat hepatocytes. Chem Res Toxicol 1996;9:1031-6. Yanada H, Oguri K, Yoshimura H. Effects of several factors on urinary excretion of methamphetamine and its metabolites in rats. Xenobiotica 1986;16:137-41. Timbrell J. 2000. Factors affecting metabolism and disposition — Enzyme inhibition. In: Principles of Biochemical Toxicology. 3 rd ed. New York (NY): Taylor and Francis; 2000. p. 164

Biol. Chem., Vol. 380, pp. 1273–1279, November 1999 · Copyright © by Walter de Gruyter · Berlin · New York Regulation of Bile Salt Export Pump mRNA Levels by Dexamethasone and Osmolarity in Cultured Rat Hepatocytes Ulrich Warskulat1, Ralf Kubitz1, Matthias Wettstein1, Bruno Stieger2, Peter J. Meier2 and Dieter Häussinger1,* 1 Clinic for Gastroenterology, Hepatology and Infectiology, Heinrich-Heine-University Düsseldorf, Germany 2 Division of Clinical Pharmacology and Toxicology, Department of Medicine, University Hospital Zürich, Switzerland * Corresponding

Protective Effects of Phenolic Compounds on CCl4-Induced Toxicity in Isolated Rat Hepatocytes M. T. Añón, A. Ubeda, and M. J. Alcaraz Departamento de Farmacologia, Facultad de Farmacia, Avda. Blasco Ibanez 13, 46010 Valencia, Spain Z. Naturforsch. 47c, 275 -2 7 9 (1992); received April 23, 1991/January 2, 1992 Flavonoids, Phenolic Acids, CC14 Hepatocytes, Hepatoprotective Agents The protective effects o f a series o f phenolic compounds, phenolic acids and flavonoids on the cytotoxicity o f CC14 in rat hepatocytes were studied. A number o f flavones, 7

multivariate data analysis . Proteomics 2004;4:868-80. 7. Rana SV, Pal R, Vaiphei K, Ola RP, Singh K. Hepatoprotection by carotenoids in isoniazid-rifampicin induced hepatic injury in rats . Biochem Cell Biol 2010;88:819-34. doi: 10.1139/o10-023 8. Hussain SM, Frazier JM. Cellular toxicity of hydrazine in primary rat hepatocytes . Toxicol Sci 2002;69:424-32. doi: 10.1093/toxsci/69.2.424 9. Chowdhury A, Santra A, Bhattacharjee K, Ghatak S, Saha DR, Dhali GK. Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice

Biol. Chem., Vol. 380, pp. 413 – 418, April 1999 · Copyright © by Walter de Gruyter · Berlin · New York Growth- and Development-Dependent Expression of Gangliosides in Rat Hepatocytes and Liver Tissues Kiyoshi Sugiyama* and Megumi Saito Department of Clinical Pharmacology and Therapeutics, University of Shizuoka School of Pharmaceutical Sciences, 52-1 Yada, Shizuoka 422-8526, Japan * Corresponding author Expression of gangliosides in the liver was examined in primary cultures of hepatocytes from adult rats and liver tissues from rats of different ages

response. Mutat. Res. 569 (2005) 29-63. 12. Beken, S., Vanhaecke, T., De Smet, K., Pauwels, M., Vercruysse, A. and Rogiers, V. Collagen-gel cultures of rat hepatocytes: collagen-gel sandwich and immobilization cultures. Method Mol. Biol. 107 (1998) 303-309. DOI: 10.1385/0-89603-519-0:303. 13. De Smet, K., Beken, S., Vanhaecke, T., Pauwels, M., Vercruysse, A. and Rogiers, V. Isolation of rat hepatocytes. Methods Mol. Biol. 107 (1998) 295-302. DOI: 10.1385/0-89603-519-0:295. 14. La Marca, M., Beffy, P., Pugliese, A. and Longo, V. A fermented powder of wheat is an inducer

Hoppe-Seyler's Z. Physiol. Chem. Bd. 357, S. 1477 -1486, November 1976 Cholic Acid Uptake into Isolated Rat Hepatocytes* M. Sawkat ANWER, Reinhard KROKER and Dietmar HEGNER Institut für Pharmakologie, Toxikologie und Pharmazie, Fachbereich Tiermedizin der Universität München (Received 2 3 July 1976) Summary: Cholic acid uptake was studied in isolated rat hepatocytes using a centrifugal filtra- tion technique to allow rapid sampling. Hepa- tocytes were found to adsorb as well as to trans- port cholic acid. The adsorption was characterized by a capacity of 24nmol