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tracking and strain reconstruction from tagged cardiac MR images without userdefined myocardial contours, J. Magn. Reson. Imaging, 2005, 21, 1, 12-22 [9] Kumar S., Goldgof D., Automatic tracking of SPAMM grid and the estimation of deformation parameters from cardiac MR images, IEEE Trans.Med. Imag., 1993, 13, 122-132 [10] Amini A.A., Chen Y., Curwen R.W., Mani V., Sun J., Coupled Bsnake grids and constrained thin-plate splines for analysis of 2-D tissue deformations from tagged MRI, IEEE Trans. Med. Imag., 1998, 17, 3, 344-356 [11] Qian Z., Huang X., Metaxas D., Axel L

for the development of congestive heart failure in individuals free of myocardial infarction. In this study we aim to investigate the relationship between homocysteine (Hcy) levels and regional left ventricular (LV) function in an asymptomatic population. Method and Results: Regional peak systolic mid-wall circumferential strains were calculated from 1178 tagged-MRI studies in participants in the Multi-Ethnic Study of Atherosclerosis (MESA). Left ventricle regions were defined by coronary territories (left anterior descending [LAD], left circumflex [LCX