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Mitomycin C-Activity Effected by Vitamins B1, C, E and -Carotene under Irradiation with γ-Rays Edith Heinrich and Nikola Getoff* Institute for Theoretical Chemistry and Structural Biology as well as Ludwig Boltzmann Institute for Radiation Chemistry and Radiation Biology, The University of Vienna, Althanstr.14, A-1090 Vienna, Austria. Fax: ++43(1)-4277-52795. E-mail: nikola.getoff@univie.ac.at * Author for correspondence and reprint requests Z. Naturforsch. 58c, 244Ð248 (2003); received October 11/November 7, 2002 Vitamin B1 (thiamine) can essentially effect the

3 Vitamin B1 – Thiamine 3.1 Nutritional and biological aspects of vitamin B1 Elena Beltramo 3.1.1 Introduction Thiamine, or vitamin B1, is a water-soluble, B-complex vitamin, necessary for the metabolism of carbohydrates, fats and proteins in most organisms (Stryer, 1988), which probably played a role in the earliest phases of the evolution of life (Frank et al., 2007). It was the first vitamin to be isolated in the first years of the 20th century, while look- ing for an ‘anti-beriberi’ substance (Lonsdale, 2006), and it was crystallized from rice polishings in

(1983), Gubler (1984), Oka (1984) Historical reviews: Wuest (1962), Ullrich, Deus & Holzer (1968), Jansen (1972), Whelan (1976), Yoshimura et al. (1976), Wakabayashi, Yui & Kawai (1979), White & Spenser (1979), Cremer (1980), Krampitz (1982), Auhagen (1982), Davis & Icke (1983), Thompson (1983), Gubler(1984), Karlson (1984) 342 6 Thiamin, Vitamin B1; Aneurin tained from rice bran. (It turned out later that this was probably nicotinic acid, however.) The isolation of the anti-beriberi factor from rice bran was first accom- plished by B.C.P. Jansen and W

developed after these symptoms has not been clarified yet. Vitamins are classified as either fat-soluble (vitamins A, D, E, and K) or water-soluble (B-complex and vitamin C). The absorption of fat-soluble vitamins is reduced in cholestatic patients [ 15 ]. Vitamins B1 and B2 are water-soluble vitamins with an important role in carbohydrate metabolism. In the deficiency of these vitamins, the oxidative degradation of glucose is reduced and glucose degradation is paused at the lactate and pyruvate levels. The present study aimed to determine the levels of total cholesterol

Z. Phys. Chem. 227 (2013) 403–417 / DOI 10.1524/zpch.2013.0276 © by Oldenbourg Wissenschaftsverlag, München Thermodynamic and Adsorption Behaviour of Vitamin B1 as a Corrosion Inhibitor for AISI 4130 Steel Alloy in HCl Solution By Ali Reza Hoseinzadeh, Iman Danaee∗, and Mohamad Hosein Maddahy Abadan Faculty of Petroleum Engineering, Petroleum University of Technology, Abadan, Iran (Received May 19, 2012; accepted in revised form December 18, 2012) (Published online March 11, 2013) Steel 4130 / Corrosion / Inhibitor / Adsorption Isotherm / Frumkin The inhibition

Introduction The role of thiamine and more specifically thiamine pyrophosphate (TPP), the active form of what is commonly known as vitamin B1, in carbohydrate metabolism is well documented. However, a broader understanding of the biological role(s) of thiamine outside of carbohydrate metabolism is not yet available. Thiamine is a water-soluble vitamin which is passively absorbed in the small intestine at high concentrations or actively absorbed through thiamine transporter proteins at lower concentrations [ 1 ]. It exists in multiple forms through the addition of

Stadium der Bj-Avitaminose zu einer Hyperftmktion der Schilddrüse kommt. Was nun die Herabsetzung des Sauerstoffverbrauches selbst betrifft, so ist es wohl fraglich, ob sie — wie dies einzelne Autoren annehmen — ausschließlich eine Folgeerscheinung der Inanition darstellt. Die vorliegenden Untersuchungen sprechen eher dagegen, da nämlich der Sauerstoffverbrauch als Folge des Vitamin B1-Mangels schon zu einem Zeitpunkte absinkt, in welchem die Tiere nicht nur nicht als hungernd anzusprechen sind, sondern im Gegenteil eine Gewichtszunahme zeigen und nach meinen

Vitamin B^Wirkungen. I 53 -freie Kost erhalten hatten. Ohne Zusatz 37,5 und 40,0 BTS je ccm Blut. Eatte 27439 nach Eiogabe von 0,4g Leberpräparat 13,0 u. 14,0 BTS Ratte 27437 „ „ „ 0,4g ,, 14,5 u. 13,5 Ratte 27436 „ „ „ 0,8g „ 11,5 u. 10,0 . 2. Brenztraubensäure im Blut nach Eingabe von Vitamin B1? Cocarboxylase und Insulin Vor einiger Zeit hat der eine von uns die Beobachtung mit- geteilt1), daß Injektionen von Aneurin sowie von Cocarboxylase und von Insulin bei gesunden Menschen nicht nur den Brenztrauben- säuregehalt des Blutes, sondern auch den Phosphatgehalt

, 4542 –4543. Zeidler , J., Sayer, B.G., and Spenser, I.D. ( 2003 ). Biosynthesis of vitamin B1 in yeast. Derivation of the pyrimidine unit from pyridoxine and histidine. Intermediacy of urocanic acid. J. Am. Chem. Soc. 125 , 13094 –13105. Zhang , Y., Taylor, S.V., Chiu, H.J., and Begley, T.P. ( 1997 ). Characterization of the Bacillus subtilis thiC operon involved in thiamine biosynthesis. J. Bacteriol. 179 , 3030 –3035. Zilles , J.L., Croal, L.R., and Downs, D.M. ( 2000 ). Action of the thiamine antagonist bacimethrin on thiamine biosynthesis. J. Bacteriol

Erfahrungen mit der Applikation der lontophorese E L . E K T R O M E D I Z I NB A N D 6/1961 Nr. l AUS DER REHABILITATIONSABTEILUNG DES OUNZ, PRAG l, (DIREKTOR: DR. J. ROTMAN) K. Z l CH A, O. Z l C H A und M. Z l C H A Die Erfahrungen mit der Applikation der lontophorese mit Vitamin B1 Die Autoren beschreiben die Applikation der Vitamin-Bi-Iontophorese, behandeln die Methodik und geben eine kurze Übersicht über die Ergebnisse der angewendeten Therapie. Wegen der Heilwirkung bei akuten und chronischen Entzündungen der peripheren Nervenzellen und ihrer Neuronen