structure demonstrated enhanced leaflet opening and closing
as a result of stent deformation and redirected loading.
Crimping and subsequent release into the AR model as well
as the stent adaption to the target region after expansion
proved the suitability of the TAV design for percutaneous
application. FEA represented a useful tool for numerical
simulation of an entire minimally invasive heart valve
prosthesis in relevant clinical scenarios.
Keywords: Finite-element analysis, transcatheter aortic
valve prosthesis, aorticrootmodel.
printing and silicone cast molding for manufacturing of aorticrootmodels with variable degree of stenosis. Design of aortic
roots with normal, mild and severe stenosis was developed
according to Reul et al. For manufacturing of tripartite cast-
ing molds, a 3D printer was used. Both outer mold parts and
the mold core were manufactured from polylactide filament
and water soluble polyvinylalcohol filament, respectively. In
vitro hydrodynamic performance testing of an exemplary
commercially available TAVP implanted in different aorticrootmodels was conducted
NonCommercial-NoDerivatives 4.0 License.
Current Directions in Biomedical Engineering 2018; 4(1): 259 – 262
2 Materials and methods
2.1 Design parameter
The geometric model used in this study consists of a generic
aorticrootmodel with three identical leaflets that are based
on previously published literature [4-5]. The aortic root was
created using computer-aided design (CAD) software Creo
Parametric 3.0 (Parametric Technology Corp., Needham,
MA, USA). The shape of the aortic root was defined by five