structure demonstrated enhanced leaflet opening and closing
as a result of stent deformation and redirected loading.
Crimping and subsequent release into the AR model as well
as the stent adaption to the target region after expansion
proved the suitability of the TAV design for percutaneous
application. FEA represented a useful tool for numerical
simulation of an entire minimally invasive heart valve
prosthesis in relevant clinical scenarios.
Keywords: Finite-element analysis, transcatheteraorticvalveprosthesis, aortic root model.
(see Figure 3). Only in the normal
aortic root a small increase from 3.2 ± 1.2% to 5.2 ± 1.0%
was measured (n = 10). Furthermore, the regurgitant fraction
increased with grade of stenosis, e.g. from 3.4 ± 1.2% in the
normal aortic root to 12.9 ± 0.8% in the mild stenotic root
and 16.1 ± 0.9% in the severe stenotic root at a cardiac output
of 5 l/min (n = 10), respectively.
Figure 3: Regurgitant fraction of a transcatheteraorticvalveprosthesis in silicone aortic root models with different grade of
stenosis as a function of the
distilled water and tempered to 37°C ± 2°C. With the help of
a pump and flow resistances (Figure 1, no. 2-4) a static pres-
sure was applied to the TAVP leading to full valve closure.
As a result, the measured regurgitation is assumed as solely
paravalvular between prosthesis skirt and annulus model.
Figure 3: Schematic of transcatheteraorticvalveprosthesis in a
silicone model of the aortic annulus and implantation depth D
which was varied in the range of 0 mm to 6 mm.
The static pressure on the valve was increased from