Autonomy has become a central theme of medico-ethical discourse in recent years - how can it be implemented at the end of life? Which practices and institutional and socio-political frameworks stand in the way? Furthermore, are there other human rights alongside the right to self-determination that are particularly at risk at the end of life? Experts from the fields of human rights, medical law, philosophy, medical ethics, literary studies, nursing, healthcare, internal medicine, palliative care, and forensic medicine provide answers to these questions. The volume is complemented by an interview with disabled rights activist Dinah Radtke on the 'surprising experience of quality of life' for people dependent on assistance and technical devices. With contributions from Jan P. Beckmann, Heiner Bielefeldt, and Oliver Tolmein, among others.