1
Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USA
2
Servier Research Institute, 125 Chemin de Ronde, 78290 Croissysur-Seine, France
3
McMaster HTS Laboratory, Department of Biochemistry and Biomedical Sciences, McMaster University, HSC 4N45-D, 1200 Main St. West, Hamilton, ON L8N 3Z5, Canada
4
AJLW Consulting, Inc., 649 Via Rialto, Oakland, CA 94619, USA
5
World Health Organization, TDR, Special Programme for Research and Training for Neglected Disease, 20 Avenue Appia, 1211 Geneva, Switzerland
6
Department of Obstetrics and Gynecology, McMaster University, HSC 3N52, 1200 Main St. West, Hamilton, ON L8N 3Z5, Canada
7
Institut für Physikalische und Theoretische Chemie, Universität Tübingen, Auf der Morgenstelle 8, D-72076 Tübingen, Germany
8
GlaxoSmithKline Pharmaceuticals, 709 Swedeland Road, King of Prussia, PA 19406, USA
9
Boehringer Ingelheim Pharmaceuticals, Inc. (retired)
10
Australian Institute of Marine Science, PMB 3, Townsville 4810, Australia
11
Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109-1055, USA
12
National Center for Natural Products Research, The University of Mississippi, P.O. Box 1848, University, MS 38677, USA
13
IFR 85 “Biomolécules et Innovations Thérapeutiques” 74 Route du Rhin BP 60024, 67401 Illkirch, France
Cite as: John Proudfoot, Olivier Nosjean, Jan Blanchard, John Wang, Dominique Besson, Denis Crankshaw, Günter Gauglitz, Robert Hertzberg, Carol Homon, Lyndon Llewellyn, Richard Neubig, Larry Walker, Pascal Villa. Glossary of Terms Used in Biomolecular Screening, Pure Appl. Chem. 83, 1129 (2011). DOI: https://doi.org/10.1351/PAC-REC-09-05-03
Abstract
Biomolecular screening is now a crucial component of the drug discovery process, and this glossary will be of use to practitioners in the field of screening and to those who interact with the screening community. The glossary contains definitions related to various aspects of the screening process such as assay types, data handling, and relevant technologies. Many of the terms used in this discipline are not covered by existing glossaries, and where they are, the definitions are often not appropriate for this field. Where appropriate, this document provides new or modified definitions to better reflect the new context. The field of biomolecular screening is multidisciplinary in nature, and this glossary, containing authoritative definitions, will be useful not only for regular practitioners, but also for those who make use of data generated during the screening process.
Comments (0)