This paper deals with Obstructive Sleep Apnea (OSA) which is a common disease characterized by partial or complete interruption of airflow during sleep owing to upper airway occlusion. Untreated OSA contributes to serious comorbidities; thus they are promising invasive and non-invasive treatments. Continuous Positive Airway Pressure (CPAP) is the most common and effective treatment for OSA, however it was rejected by patients after a short period of time because of its discomfort. Therefore, an alternative therapy for this population was required. Functional electrical stimulation FES of Hypoglossal nerve (HGN) has been investigated by multiple groups. Here we have compared between the mechanisms and clinical studies of published implants. A new method for detecting the onset of OSA based on esophageal pressure Pes parameter was demonstrated (threshold −13.5 cm H2O). According to the stimulation of HGN, it necessitated values range between 33-38 Hz for decline pharyngeal narrowing.
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