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Organophosphorus Chemistry

Novel Developments

Ed. by Keglevich, György

With contrib. by Ábrányi-Balogh, Péter / Bagi, Péter / Bálint, Erika / Banerjee, Bubun / Brahmachari, Goutam / Czismadia, Imre G. / Grün, Alajos / Henyecz, Réka / Herbay, Réka / Huszthy, Péter / Kánai, Károly / Kiss, Nóra Zs. / Kóvacs, Tamara / Milen, Mátyás / Mucsi, Zoltán / Nagy, Dávid Illés / Rádai, Zita / Szabó, Tamás / Szabó-Szentjóbi, Hajnalka / Tajti, Ádám / Tóth, Tünde / Tripolszky, Anna

eBook (PDF)
Publication Date:
April 2018
Copyright year:
2018
ISBN
978-3-11-053583-9
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6. Synthesis of α-aminophosphonates by the Kabachnik–Fields reaction and by the Pudovik reaction

Bálint, Erika / Tripolszky, Anna / Tajti, Ádám

Abstract

α-Aminophosphonates are of significant importance due to their biological activity. The most widely applied synthetic routes towards α-aminophosphonates are the Kabachnik-Fields reaction involving the condensation of amines, oxo compounds and >P(O)H species, such as dialkyl phosphites, and the Pudovik reaction of imines and >P(O)H reagents. By the double Kabachnik-Fields reaction, bis(aminophosphonates) have also became available. This chapter summarizes the synthesis of α-aminophosphonates and related derivatives through the two main routes as described in the literature over the last five years.

Citation Information

Erika Bálint, Anna Tripolszky, Ádám Tajti (2018). 6. Synthesis of α-aminophosphonates by the Kabachnik–Fields reaction and by the Pudovik reaction. In György Keglevich (Editor), Organophosphorus Chemistry: Novel Developments (pp. 108–147). Berlin, Boston: De Gruyter. https://doi.org/10.1515/9783110535839-006

Book DOI: https://doi.org/10.1515/9783110535839

Online ISBN: 9783110535839

© 2018 Walter de Gruyter GmbH, Berlin/Munich/BostonGet Permission

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