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Acta Veterinaria

The Journal of University of Belgrade

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CiteScore 2016: 0.65

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1820-7448
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Nasal Transmissible Venereal Tumor In A Jack Russel Terrier Bitch

NAZALNI TRANSMISIVNI VENERIČNI TUMOR KOD KUJE RASE JACK RUSSEL

FEGHIU Adrian
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  • University of Agronomical Sciences and Veterinary Medicine of Bucharest, Romania, Faculty of Veterinary Medicine
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/ CRÎNGANU Dan
  • University of Agronomical Sciences and Veterinary Medicine of Bucharest, Romania, Faculty of Veterinary Medicine
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/ DUMITRESCU Florin
  • University of Agronomical Sciences and Veterinary Medicine of Bucharest, Romania, Faculty of Veterinary Medicine
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/ PASCAL Manuela
  • University of Agronomical Sciences and Veterinary Medicine of Bucharest, Romania, Faculty of Veterinary Medicine
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/ VASILESCU Florina
  • National Institute for Research and Development in Pathology and Biomedical Sciences Victor Babes, Bucharest, Romania
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/ MILITARU Manuella
  • University of Agronomical Sciences and Veterinary Medicine of Bucharest, Romania, Faculty of Veterinary Medicine
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Published Online: 2015-03-20 | DOI: https://doi.org/10.1515/acve-2015-0012

Abstract

A two-year old Jack Russell Terrier female with left-sided epistaxis was brought to the Clinic of the Bucharest Faculty of Veterinary Medicine. Endoscopy of the left nasal cavity revealed a cauliflower-like mass. Cytological and histopathological features were specific to canine transmissible venereal tumour (CTVT). Tumor tissue showed positive immunoreactivity to anti-vimentin monoclonal antibody (90%) and Ki67 (35%) and samples were negative for anti-cytokeratin monoclonal antibody. Chemotherapy with vincristine sulphate at a dose of 0.025 mg/kg i.v./week for 6 administrations was successful. This paper presents a primary form of nasal CTVT in a Jack Russell Terrier female.

Na klinici Fakulteta veterinarske medicine u Bukureštu, prezentovana je dve godine stara kuja rase Jack Russel sa epistaks krvavljenjem iz leve nozdrve. Endoskopijom leve nosne šupljine ustanovljena je masa karfiolaste strukture. Citološke i histopatološke karakteristike su odgovarale karakteristikama specifičnim za transmisivni venerični tumor (TVT) pasa. Tumor je bio imunohistohemijski pozitivan na anti-vimentin monoklonsko antelo (90%) kao i na Ki67 (35%), a negativan na anti-citokeratin monoklonsko antitelo. Hemoterapija sa vinikristin sulfatom, u dozi od 0.025 mg/kg telesne mase datog intravenski jedanput nedeljno, u trajanju od ukupno 6 nedelja, bila je uspešna. U radu se prikazuje primarna forma nazalnog TVT kod ženke rase Jack Russel terijera.

Keywords: canine transmissible venereal tumor; complex diagnosis; nasal localisation

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About the article

Received: 2014-04-16

Accepted: 2014-12-26

Published Online: 2015-03-20

Published in Print: 2015-03-01


Citation Information: Acta Veterinaria, Volume 65, Issue 1, Pages 143–148, ISSN (Online) 1820-7448, DOI: https://doi.org/10.1515/acve-2015-0012.

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© FEGHIU Adrian, CRÎNGANU Dan, DUMITRESCU Florin, PASCAL Manuela, VASILESCU Florina, MILITARU Manuella. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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