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European Pharmaceutical Journal

Acta Facultatis Pharmaceuticae Universitatis Comenianae (formerly)

2 Issues per year

CiteScore 2016: 0.28

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Comparison of classic and derivative UV spectrophotometric methods for determination of dextromethorphani hydrobromidum

J. Drozd
Published Online: 2012-08-13 | DOI: https://doi.org/10.2478/v10219-012-0014-8

Comparison of classic and derivative UV spectrophotometric methods for determination of dextromethorphani hydrobromidum

A method for the fast determination of dextromethorphani hydrobromidum in pharmaceutical preparations by classic spectrophotometry - zero and first-, second- and third-order derivative spectrophotometry, using "peak - peak" (P - P) and "peak - zero" (P - O) measurements has been performed. The calibration curves are linear within the concentration range of 1.0 - 25.0 μg ml-1 for dextromethorphani hydrobromidum. The procedure is simple, rapid and the results are reliable.

Keywords: Dextromethorphani hydrobromidum; classic spectrophotometry; derivative spectrophotometry

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About the article

Published Online: 2012-08-13

Published in Print: 2012-01-01

Citation Information: Acta Facultatis Pharmaceuticae Universitatis Comenianae, Volume 59, Issue 1, Pages 22–29, ISSN (Print) 0301-2298, DOI: https://doi.org/10.2478/v10219-012-0014-8.

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