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Anthropological Review

The Journal of Polish Anthropological Society

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2083-4594
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Mycolic Acids as Markers of Osseous Tuberculosis in the Neolithic Skeleton from Kujawy Region (Central Poland)

Beata Borowska-Strugiń
  • Corresponding author
  • Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Poland
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/ Magdalena Druszczyńska
  • Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology ad Environmental Protection, University of Łódź, Poland
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/ Wiesław Lorkiewicz
  • Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Poland
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/ Rafał Szewczyk
  • Department of Biotechnology and Industrial Microbiology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology ad Environmental Protection, University of Łódź, Poland
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/ Elzbieta Ządzińska
  • Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Poland
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Published Online: 2014-07-15 | DOI: https://doi.org/10.2478/anre-2014-0012

Abstract

The subject of analysis is the male skeleton from a double burial of the Globular Amphora Culture, derived from the Neolithic site at Brześć Kujawski in Kujawy region (central Poland). Within the spine of the individual advanced lesions are observed (destruction of the vertebral bodies, symptoms of the periostitis in the thoracic region) which are characteristic of skeletal tuberculosis. To check whether the observed morphological changes resulted from infection with Mycobacterium tuberculosis (M.tb), the bone material was tested positively for the presence of mycolic acids, the specific components of the cell wall of pathogenic M.tb bacilli, by mass spectrometry.

Keywords: mycolic acids; paleopathology; Neolithic

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About the article

*Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland


Received: 2013-12-19

Accepted: 2014-04-24

Published Online: 2014-07-15


Citation Information: Anthropological Review, ISSN (Online) 2083-4594, DOI: https://doi.org/10.2478/anre-2014-0012.

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© 2014 Anthropological Review. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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