Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Annals of Animal Science

The Journal of National Research Institute of Animal Production

4 Issues per year


IMPACT FACTOR 2016: 0.731

CiteScore 2016: 0.79

SCImago Journal Rank (SJR) 2016: 0.345
Source Normalized Impact per Paper (SNIP) 2016: 0.687

Open Access
Online
ISSN
2300-8733
See all formats and pricing
More options …

A Review on Effects of Aloe Vera as a Feed Additive in Broiler Chicken Diets

Darabighane Babak / Samuel N. Nahashon
Published Online: 2014-07-29 | DOI: https://doi.org/10.2478/aoas-2014-0026

Abstract

Prohibition of application of antibiotic growth promoters in broiler chicken diets has resulted in increased use of herbs as natural additives in broiler feeds over the recent years. Researchers particularly look for herbs that can affect such parameters as growth performance, immune response, or treatment of certain diseases. Aloe vera is a well-known herb characterized by properties such as anti-bacterial, anti-viral, anti-fungal, anti-tumor, anti-inflammatory, immunomodulatory, wound-healing, anti-oxidant, and anti-diabetic effects. During the past years, attention has shifted toward Aloe vera as a natural additive to broiler diets, and studies have shown that Aloe vera can improve immune response and growth performance in broilers. In addition, Aloe vera is an excellent alternative for antibiotic growth promoters and anticoccidial drugs. Since Aloe vera can be used for broilers in the form of gel, powder, ethanolic extract, aqueous extract, and a polysaccharide contained in Aloe vera gel (i.e. acemannan), more studies are required to determine the best form and to compare Aloe vera with other medicinal herbs. This paper reviews effects of Aloe vera on intestinal microflora, growth performance, immune response, and coccidiosis in broiler chickens.

Keywords: broiler chicken; Aloe vera; microflora; immune system; growth performance; coccidiosis

References

  • Agarry O.O., Olaleye M.T., Bello - Michael C.O. (2005). Comparative antimicrobial activities of Aloe vera gel and leaf. Afr. J. Biotechnol., 4: 1413–1414.Google Scholar

  • Ahlawat K.S., Khatkar B.S. (2011). Processing, food applications and safety of Aloe vera products: a review. J. Food Sci. Technol., 48: 525–533.CrossrefGoogle Scholar

  • Akhtar M., Hai A., Awais M.M., Iqbal Z., Muhammad F., Anwar M.I. (2012). Immunostimulatory and protective effects of Aloe vera against coccidiosis in industrial broiler chickens. Vet. Parasitol., 186: 170–177.Web of ScienceGoogle Scholar

  • Alemdar S., Agaoglu S. (2009). Investigation of in vitro antimicrobial activity of Aloe vera juice. J. Anim. Vet. Adv., 8: 99–102.Google Scholar

  • Alemi F., Mahdavi A., Ghazvinian K., Ghaderi M., Darabighane B. (2012). The effects of different levels of Aloe vera gel powder on antibody titer against Newcastle disease virus and performance in broilers. Proc. International Poultry Scientific Forum, Georgia World Congress Center, Atlanta, Georgia, 23–24.01.2012, p. 47.Google Scholar

  • Altuğ N., Yüksek N., Ağaoğlu Z.T. (2010). Immunostimulatory effects of Aloe vera and β-Glucan on cellular and humoral immune responses following vaccination with polyvalent vaccines in dogs. J. Fac. Vet. Med., University of Kafkas, Kars, 16: 405–412.Google Scholar

  • Besharatian M., Arshami J., Valizade R., Tahmasebi A., BahariKashani R. (2012). Effects of Aloe vera leaf powder and extract on immune response in broilers. Proc. 5th Iranian Congress on Animal Science, Isfahan, Iran, pp. 366–370.Google Scholar

  • Boudreau M.D., Beland F.A. (2006). An evaluation of the biological and toxicological properties of Aloe barbadensis (Miller), Aloe vera. J. Environ. Sci. Heal. C., 24: 103–154.Google Scholar

  • Chinnah A.D., Baig M.A., Tizard I.R., Kemp M.C. (1992). Antigen dependent adjuvant activity of a polydispersed beta-(1, 4)-linked acetylated mannan (acemannan). Vaccine, 10: 551–557.Google Scholar

  • Choi S., Chung M.-H. (2003). A review on the relationship between Aloe vera components and their biologic effects. Semin. Integr. Med., 1: 53–62.CrossrefGoogle Scholar

  • Christaki E.V., Florou - Paneri P.C. (2010). Aloe vera: A plant for many uses. J. Food Agric. Environ., 8: 245–249.Google Scholar

  • Dai B., Jiang L., Chen S. (2007). Effects of medicinal herb and polysaccharide from Aloe on gut microflora, immune function and growth performance in broiler. China Poultry., 29: 21–24.Google Scholar

  • Darabighane B., Zarei A. (2011). The effects of the different levels of Aloe vera gel on oocysts shedding in broilers with coccidiosis. Planta Med., 77: PN2.CrossrefGoogle Scholar

  • Darabighane B., Zarei A., Zare Shahneh A., Mahdavi A. (2011 a). A study on the effects of Aloe vera gel on phagocytic ability of macrophages and blood parameters in broilers. Poultry Sci., 90 (E-Suppl. 1): p. 128.Google Scholar

  • Darabighane B., Zarei A., Zare Shahneh A., Mahdavi A. (2011 b). Effects of different levels of Aloe vera gel as an alternative to antibiotic on performance and ileum morphology in broilers. Ital. J. Anim. Sci., 10: 189–194.Google Scholar

  • Darabighane B., Zarei A., Shahneh A.Z. (2012). The effects of different levels of Aloe vera gel on ileum microflora population and immune response in broilers: a comparison to antibiotic effects. J. Appl. Anim. Res., 40: 31–36.CrossrefWeb of ScienceGoogle Scholar

  • Djeraba A., Quere P. (2000). In vivo macrophage activation in chickens with Acemannan, a complex carbohydrate extracted from Aloe vera. Int. J. Immunopharmaco., 22: 365–372.CrossrefGoogle Scholar

  • Eshun K., He Q. (2004). Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries. a review. Crit. Rev. Food Sci., 44: 91–96.CrossrefGoogle Scholar

  • Femenia A., Sanchez E.S., Simal S., Rossello C. (1999). Compositional features of polysaccharides from Aloe vera (Aloe barbadensis Miller) plant tissues. Carbohyd. Polym., 39: 109–117.CrossrefGoogle Scholar

  • Feng Y.Z., Gu F.X., Yuan Z.X., Zhang Y.J., Liu S.H., Hu L.L., Xu L. (2011). Effects of Aloe polysaccharide on immune organ index and immune efficacy of vaccine against Newcastle disease in broiler. J. Henan Agricult. Univ., 45: 432–436.Google Scholar

  • Guo F., Williams B., Kwakkel R., Verstegen M. (2003). In vitro fermentation characteristics of two mushroom species, an herb, and their polysaccharide fractions, using chicken cecal contents as inoculum. Poultry Sci., 82: 1608–1615.CrossrefGoogle Scholar

  • Guo F., Kwakkel R., Williams B., Parmentier H., Li W., Yang Z., Verstegen M. (2004 a). Effects of mushroom and herb polysaccharides on cellular and humoral immune responses of Eimeria tenella-infected chickens. Poultry Sci., 83: 1124–1132.CrossrefGoogle Scholar

  • Guo F.C., Williams B.A., Kwakkel R.P., Li H.S., Li X.P., Luo J.Y., Li W.K., Verstegen M.W.A. (2004 b). Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Poultry Sci., 83: 175–182.CrossrefGoogle Scholar

  • Hamman J.H. (2008). Composition and applications of Aloe vera leaf gel. Molecules., 13: 1599–1616.Web of ScienceCrossrefPubMedGoogle Scholar

  • Hardy B. (2002). The issue of antibiotic use in the livestock industry: what have we learned? Anim. Biotechnol., 13: 129–147.CrossrefPubMedGoogle Scholar

  • Harlev E., Nevo E., Lansky E.P., Ofir R., Bishayee A. (2012). Anticancer potential of Aloes: antioxidant, antiproliferative, and immunostimulatory attributes. Planta Med., 78: 843–852.Web of SciencePubMedGoogle Scholar

  • Hassanbeigy - Lakeh Z., Roustaee Ali - Mehr M., Haghighian - Roudsari M. (2012). Effect of Aloe gel on broiler performance. Proc. 5th Iranian Congress on Animal Science, Isfahan, Iran, pp. 973–977.Google Scholar

  • He C.L., Fu B.D., Shen H.Q., Jiang X.L., Wei X.B. (2011). Fumaric acid, an antibacterial component of Aloe vera L. Afr. J. Biotechnol., 10: 2973–2977.Google Scholar

  • Jiang L., Feng Y., Yang X., Zhou X., Yang D. (2005). Effects of gel, polysaccharide and acemannan from Aloe vera on broiler gut flora, microvilli density, immune function and growth performance. Chinese J. Vet. Sci., 25: 668–671.Google Scholar

  • Karaca K., Sharma J.M., Nordgren R. (1995). Nitric oxide production by chicken macrophages activated by Acemannan, a complex carbohydrate extracted from Aloe vera. Int. J. Immunopharmaco., 17: 183–188.CrossrefGoogle Scholar

  • Kwon K.H., Hong M.K., Hwang S.Y., Moon B.Y., Shin S., Baek J.H., Park Y.H. (2011). Antimicrobial and immunomodulatory effects of Aloe vera peel extract. J. Med. Plants Res., 5: 5384–5392.Google Scholar

  • Mahdavi A., Alemi F., Ghazvinian K., Ghaderi M., Darabighane B. (2012). Study of effects of different levels of Aloe vera gel powder on antibody titre against sheep red blood cells and other blood parameters in broilers. Abstracts 2012, British Poultry Abstracts, 8: 49–50.Google Scholar

  • Mbanga J., Mangoma N., Saidi B. (2010). An evaluation of the antimicrobial activities of Aloe barbadensis, A. chabaudii and A. arborescens leaf extracts used in folklore veterinary medicine in Zimbabwe. J. Anim. Vet. Adv., 9: 2918–2923.Google Scholar

  • McAnalley B.H. (1989). Process for preparation of aloe products, Google Patents.Google Scholar

  • Mehala C., Moorthy M. (2008). Effect of Aloe vera and Curcuma longa (turmeric) on carcass characteristics and biochemical parameters of broilers. Int. J. Poultry Sci., 7: 857–861.Google Scholar

  • Mmereole F. (2011). Evaluation of the dietary inclusion of Aloe vera as an alternative to antibiotic growth promoter in broiler production. Pakistan J. Nutr., 10: 1–5.Google Scholar

  • Mwale M., Bhebhe E., Chimonyo M., Halimani T.E. (2005). Use of herbal plants in poultry health management in the Mushagashe small-scale commercial farming area in Zimbabwe. Int. J. Appl. Res. Vet. M., 3: 163–170.Google Scholar

  • Mwale M., Bhebhe E., Chimonyo M., Halimani T. (2006). The in vitro studies on the effect of Aloe vera ((L.) Webb. and Berth.) and Aloe spicata (L. f.) on the control of coccidiosis in chickens. Int. J. Appl. Res. Vet. M., 4: 128–133.Google Scholar

  • Olupona J.A., Omotoso O.R., Adeyeye A.A., Kolawole O.D., Airemionkhale A.P., Adejinmi O.O. (2010). Effect of aloe vera juice application through drinking water on performance, carcass characteristics, hematology and organoleptics properties in broilers. Poultry Sci., 88 (E-Suppl. 1): p. 42.Google Scholar

  • Pandey R., Mishra A. (2010). Antibacterial activities of crude extract of Aloe barbadensis to clinically isolated bacterial pathogens. Appl. Biochem. Biotech., 160: 1356–1361.CrossrefGoogle Scholar

  • Shokraneh M., Ghalamkari Gh., Toghyani M., Tabeidian S.A., Taghizadeh M., Landy N., Fekri F. (2012). Effect of Aloe vera (Aloe barbadensis Miller) gel in drinking water on some of the immune responses in broiler chickens. Proc. 5th Iranian Congress on Animal Science, Isfahan, Iran, pp. 791–795.Google Scholar

  • Sinurat A.P., Purwadaria T., Togatorop M.H., Pasaribu T., Bintang I.A.K., Sitompul S., Rosida J. (2002). Responses of broilers to Aloe vera bioactives as feed additive: the effect of different forms and levels of bioactives on performances of broilers. Jurnal Ilmu Ternak dan Veteriner, 7: 69–75.Google Scholar

  • Sun Z., Wei K., Yan Z., Zhu X., Wang X., Wang H., Tan Y., Sheng P., Zhu R. (2011). Effect of immunological enhancement of aloe polysaccharide on chickens immunized with Bordetella avium inactivated vaccine. Carbohyd. Polym., 86: 684–690.CrossrefGoogle Scholar

  • Tizard I.R., Ni Y. (1998). Carbohydrates, immune stimulating. In: Encyclopedia of immunology, Delves P.J., Roitt I.M. (eds). Academic Press Inc., San Diego, CA, 2nd ed., pp. 427–431.Google Scholar

  • Valle - Paraso M., Vidamo P., Anunciado R., Lapitan A. (2005). Effects of Aloe vera (Aloe barbadensis) on the white blood cell count and antibody titre of broiler chickens vaccinated against Newcastle disease. Philipp. J. Vet. Med., 42: 49–52.Google Scholar

  • Verstegen M.W., Williams B.A. (2002). Alternatives to the use of antibiotics as growth promoters for monogastric animals. Anim. Biotechnol., 13: 113–127.CrossrefPubMedGoogle Scholar

  • Waihenya R., Mtambo M., Nkwengulila G. (2002). Evaluation of the efficacy of the crude extract of Aloe secundiflora in chickens experimentally infected with Newcastle disease virus. J. Ethnopharmacol., 79: 299–304.CrossrefGoogle Scholar

  • Yang Y., Iji P., Choct M. (2009). Dietary modulation of gut microflora in broiler chickens: a review of the role of six kinds of alternatives to in-feed antibiotics. World Poultry Sci. J., 65: 97–114.Web of ScienceCrossrefGoogle Scholar

  • Yim D., Kang S.S., Kim D.W., Kim S.H., Lillehoj H.S., Min W. (2011). Protective effects of Aloe vera-based diets in Eimeria maxima-infected broiler chickens. Exp. Parasitol., 127: 322–325.PubMedCrossrefGoogle Scholar

  • Zhang L., Tizard I.R. (1996). Activation of a mouse macrophage cell line by acemannan: The major carbohydrate fraction from Aloe vera gel. Immunopharmacology, 35: 119–128.CrossrefPubMedGoogle Scholar

About the article

Received: 2013-10-16

Accepted: 2014-01-03

Published Online: 2014-07-29


Citation Information: Annals of Animal Science, Volume 14, Issue 3, Pages 491–500, ISSN (Online) 2300-8733, DOI: https://doi.org/10.2478/aoas-2014-0026.

Export Citation

© 2014 Darabighane Babak and Samuel N. Nahashon. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

[1]
Meixiu Jiang, Kan Deng, Chunling Jiang, Mingui Fu, Chunlan Guo, Xiaolei Wang, Xin Wang, Fanjing Meng, Shaoguo Yang, Keyu Deng, Tingtao Chen, and Hongbo Xin
Mediators of Inflammation, 2016, Volume 2016, Page 1
[2]
Thangarasu Muthamilselvan, Tien-Fen Kuo, Yueh-Chen Wu, and Wen-Chin Yang
Evidence-Based Complementary and Alternative Medicine, 2016, Volume 2016, Page 1
[3]
N. Bernard, A. Mohammed, A. Edwards, and P. Bridgemoha
International Journal of Poultry Science, 2016, Volume 15, Number 1, Page 15

Comments (0)

Please log in or register to comment.
Log in