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Acta Parasitologica

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Volume 60, Issue 4

Issues

Demodex mites as potential etiological factor in chalazion – a study in Poland

Witold Tarkowski / Marta Owczyńska / Anna Błaszczyk-Tyszka / Daniel Młocicki
  • Department of General Biology and Parasitology, Medical University of Warsaw, ul. Chałubińskiego 5, Warsaw, Poland
  • W. Stefański Institute of Parasitology, Polish Academy of Sciences, ul. Twarda 51/55, 00-818 Warsaw, Poland
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Published Online: 2015-09-25 | DOI: https://doi.org/10.1515/ap-2015-0110

Abstract

The aim of the study was to investigate the presence of Demodex in the hair follicles of eyelashes and their potential participation in the aetiology of chalazion in patients in Poland. The study of the correlation between the presence of Demodex spp. and chalazion has never been performed in patients in Europe. There is, therefore, a justified necessity to check whether Demodex mites can be a potential risk factor in the development of chalazion in the European population. The samples were examined by light microscope, using standard parasitological methods. A positive result was assumed in the presence of Demodex spp. Demodex was detected in 91.67% of patients with a chalazion. The presence of Demodex was found in subjects from all examined age groups. The results of statistical analysis unambiguously determined the existence of an interrelationship between the presence of Demodex and chalazion. Our results clearly indicate the existence of a correlation between the occurrence of Demodex spp. and chalazion. Confirmation of the positive correlation between Demodex and chalazion in a European population provides further evidence for the pathogenic role of Demodex in the development of eye diseases.

Keywords: Demodex; Demodex folliculorum; Demodex brevis; inflammation; cilium hair follicle; chalazion

References

  • Akbulatova L.K. 1963. The pathogenic role of Demodex mite and the clinical form of demodicosis in man. (in Russian). Vestnik Dermatologii i Venerologii, 40, 57-61Google Scholar

  • Akilov O.E., Mumcuoglu K.Y. 2003. Association between human demodicosis and HLA class. Journal of Clinical and Experimental Dermatology, 28, 70-73Google Scholar

  • Baima B. Sticherling M. 2002. Demodicidosis revisited. Acta Dermato- Venerologica, 82, 3-6Google Scholar

  • Bonnar E., Eustace P., Powell F.C. 1993. The Demodex mite population in rosacea. Journal of the American Academy of Dermatology, 28, 443-448Google Scholar

  • Bradford C.A. (Ed.) 2004. Basic Ophthalmology. 8th Edition. American Academy of Ophthalmology. USA. pp. 219Google Scholar

  • Browning D, Proia A. 1986. Ocular rosacea. Survey of Ophthalmology, 31, 145-158Google Scholar

  • Desch C., Nutting W.B. 1972. Demodex folliculorum (Simon) and Demodex brevis (Akbulatova) of man: redescription and reevaluation. Journal of Parasitology, 58, 169-177Google Scholar

  • Desch C., Nutting W.B. 1977: Morphology and functional anatomy of Demodex folliculorum (Simon) of man. Acarologia, 19, 422-462 v. Hippel E. 1932. Demodex folliculorum im Chalazion. Albrecht von Graefes Archiv fur Ophthalmologie, 129, 198-204Google Scholar

  • Humiczewska M. 1991. Demodex folliculorum and Demodex brevis (Acardia) as the factors of chronic marginal blepharitis. Wiadomości Parazytologiczne, 37, 127-130Google Scholar

  • Jarmuda S., O’Reilly N., Zaba R., Jakubowicz O., Szkaradkiewicz A., Kavanagh K. 2012. Potential role of Demodex mites and bacteria in the induction of rosacea. Journal of Medical Microbiology, 61, 1504-1510. DOI: 10.1099/jmm.0.048090-0Web of ScienceCrossrefGoogle Scholar

  • Kamoun B., Fourati M., Feki J., Mlik M., Karray F., Trigui A., Ellouze S., Hammami B., Chaabouni M., Ayadi A. 1999. Blepharitis due to Demodex: myth or reality? (In French). Journal francais d’ophthalmologie, 22, 525-527Google Scholar

  • Kanski J.J., Bowling B. (Eds). 2011. Clinical Ophthalmology: A Systematic Approach. 7th Edition. Elsevier Health Sciences, USA, pp. 920Google Scholar

  • Kligman A.M., Christensen M.S. 2011. Demodex folliculorum: requirements for understanding its role in human skin disease. Journal of Investigative Dermatology, 131, 8-10. DOI: 10.1038/jid.2010.335Web of ScienceCrossrefGoogle Scholar

  • Lacey N., Delaney S., Kavanagh K., Powell F.C. 2007. Mite-related bacterial antigens stimulate inflammatory cells in rosacea. British Journal of Dermatology, 157, 474-481Web of ScienceGoogle Scholar

  • Lacey N., Kavanagh K., Tseng S.C. 2009. Under the lash: Demodex mites in human diseases. Biochem (Lond), 31, 2-6Google Scholar

  • Lacey N., Ni Raghallaigh S., Powell F.C. 2011. Demodex mitescommensals, parasites or mutualistic organisms? Dermatology, 222, 128-130. DOI: 10.1159/000323009CrossrefWeb of ScienceGoogle Scholar

  • Liang L., Ding X., Tseng S.C. 2014. High prevalence of Demodex brevis infestation in chalazia. American Journal of Ophthalmology, 157, 342-348. DOI: 10.1016/j.ajo.2013.09.031Web of ScienceCrossrefGoogle Scholar

  • Pena G.P., Andrade Filho J.S. 2000. Is Demodex really non-pathogenic? Revista do Instituto de Medicina Tropical de Sao Paulo, 42, 171-173 Google Scholar

  • Raszeja-Kotelba B., Pecold K., Pecold-Stępniewska H., Dadej I. 2004. Ocular rosacea - current etiopathogenetic, clinical and therapeutic data, and a description of three cases. (In Polish). Advances in Dermatology and Allergology, 21, 144-150Google Scholar

  • Sönmez O.U., Yalcın Z.G., Karakece E., Ciftci I.H., Erdem T. 2013. Associations between Demodex species infestation and various types of cancer. Acta Parasitologica, 58, 551-555, DOI: 10.2478/s11686-013-0178-y Web of ScienceCrossrefGoogle Scholar

  • Wolf R., Ophir J., Avigat J., Lengy J., Krakowski A. 1988. The hair follicle mites (Demodex spp.) Could they be vectors of pathogenic microorganisms? Acta Dermato-Venereologica, 68, 535-537Google Scholar

  • Yam J.C., Tang B.S., Chan T.M., Cheng A.C. 2014. Ocular demodicidosis as a risk factor of adult recurrent chalazion. European Journal of Ophthalmology, 24, 159-63. DOI: 10.5301/ejo. 5000341 CrossrefWeb of ScienceGoogle Scholar

About the article

Received: 2015-03-17

Revised: 2015-06-23

Accepted: 2015-06-25

Published Online: 2015-09-25

Published in Print: 2015-12-01


Citation Information: Acta Parasitologica, Volume 60, Issue 4, Pages 777–783, ISSN (Online) 1896-1851, ISSN (Print) 1230-2821, DOI: https://doi.org/10.1515/ap-2015-0110.

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