Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Acta Parasitologica

4 Issues per year


IMPACT FACTOR 2017: 1.039
5-year IMPACT FACTOR: 1.121

CiteScore 2017: 1.17

SCImago Journal Rank (SJR) 2017: 0.641
Source Normalized Impact per Paper (SNIP) 2017: 0.738

Online
ISSN
1896-1851
See all formats and pricing
More options …
Volume 63, Issue 4

Issues

Prevalence of non-pathogenic types of gastrointestinal protozoa in population in Slovakia and their potential importance in the aspect of public health

Adriána Dudlová
  • St Elisabeth University of Health Care and Social Work, Námestie 1. mája, 080 00 Bratislava, Slovak Republic
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Pavol Jarčuška
  • Department of Infectology and Travel Medicine, Faculty of Medicine, University of P. J. Šafárik, Rastislavova 43, 041 90 Košice, Slovak Republic
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Silvia Jurišová / Zuzana Vasilková
  • Institute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovak Republic
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Vladimír Krčméry
  • St Elisabeth University of Health Care and Social Work, Námestie 1. mája, 080 00 Bratislava, Slovak Republic
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Peter Juriš
  • Corresponding author
  • Department of Epidemiology, Faculty of Medicine, University of P. J. Šafárik, Šrobárova 2, 041 80 Košice, Slovak Republic
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2018-10-18 | DOI: https://doi.org/10.1515/ap-2018-0100

Abstract

The aim of the research was to determine the prevalence of non-pathogenic protozoa circulating in the human population of Slovakia. We particularly focused on the socially deprived areas with poor sanitation conditions, as they are one of the factors affecting the transmission of these infections. Within this study, 2760 people were coprologically screened for the presence of protozoan cysts. The analyzed group comprised 1173 men and 1587 women from different regions of Slovakia. The total prevalence (2.03%) of non-pathogenic protozoa species was determined. The prevalence of Entamoeba coli was 0.80%, the prevalence of Endolimax nana 0.58%, and the prevalence of Blastocystis hominis was 0.65%. The presence of non-pathogenic protozoa was more frequent in women than that in men, in all age groups. The highest incidence of Entamoeba coli was found in children aged one month – seven years (0.79%), the lowest in the age group of 19–88 years (0.66%). Endolimax nana was most frequent in 8–18 year-olds (0.95%), where the statistical significance was found (p<0.05). The prevalence of Blastocystis hominis by the age group ranged from 0.39 to 0.95%. We did not find any statistical significance (p>0.05) for Entamoeba coli, and similarly for Blastocystis hominis associated with the sex and age. Although the circulation of non-pathogenic protozoa in the human population is far from being limited to the developing countries, their occurrence is also frequent in the population of developed countries. Despite their controversial pathogenicity, they should not be neglected, particularly in the patients with gastrointestinal symptoms.

Keywords: Non-pathogenic gastrointestinal protozoa; human; poor sanitation conditions

References

  • Alfellani M.A., Stensvold C.R., Vidal-Lapiedra A., Onuoha E.S., Fagbenro-Beyioku A.F., Clark C.G. 2013. Variable geographic distribution of Blastocystis subtypes and its potential implications. Acta Tropica, 126, 11–18. CrossrefGoogle Scholar

  • Angelov I., Lukanov T., Tsvetkova N., Petkova V., Nicoloff G. 2008. Clinical, immunological and parasitological parallels in patients with blastocystosis. Journal of IMAB- Annual Procceding (Scientific Papers), 14, 55–58Google Scholar

  • Azami M., Sharifi M., Hejazi S.H., Tazhibi M. 2010. Intestinal parasitic infections in renal transplant recipients. Brazilian Journal of Infectious Diseases, 14, 1413–8670. CrossrefGoogle Scholar

  • Constenla M., Padrós F., Palenzuela O. 2014. Endolimax piscium sp. nov. (Amoebozoa), causative agent of systemic granulomatous disease of cultured sole, Solea senegalensis Kaup. Journal of Fish Diseases, 37, 229–240. CrossrefGoogle Scholar

  • Coyle Ch.M., Varughese J., Weiss L.M., Tanowitz H.B. 2013. Blastocystis: to treat or not to treat... Clinical Infectious Diseases, 54, 105–110. CrossrefGoogle Scholar

  • Diaczok B.J., Rival J. 1987. Diarrhea due to Blastocystis hominis: an old organism revisited. Southern Medical Journal, 80, 931–932Google Scholar

  • Dudlová A., Juriš P., Jurišová S., Jarčuška P., Krčméry V. 2016. Epidemiology and geographical distribution of gastrointestinal parasitic infection in humans in Slovakia. Helminthologia, 53, 309–317. CrossrefGoogle Scholar

  • Graczyk T.K., Shiff C.K., Tamang L., Munsaka F., Beitin A.M., Moss W.J. 2005. The association of Blastocystis hominis and Endolimax nana with diarrheal stools in Zambian schoolage children. Parasitology Research, 98, 38–43. CrossrefGoogle Scholar

  • Grym J., Kobliha J. 2004. Je infestace komenzálními amébami vždy skutečně asymptomatická? [Is infestation by commensal amoeba always really asymptomatic?] Pediatrie pro praxi, 2, 93–95. (In Czech)Google Scholar

  • Gupta M., Sinha M., Raizada N. 2008. Opportunistic intestinal protozoan parasitic infection in HIV positive patient in Jamnagar, Gujarat. SAARC Journal of Tuberculosis Lung Diseases & HIV/AIDS, 5, 1–4Google Scholar

  • Issa R. 2014. Non-pathogenic protozoa (Review article). International Journal of Pharmacy and Pharmaceutical Sciences, 6, 30–40Google Scholar

  • Juriš, P., Dudlová, A., Fábry, J., Melter, J., Miškovská, M., Mindžáková, E., et al. 2014. Endoparasitoses in hospitalised paediatric patients with pulmonary disease. Helminthologia, 51, 98–102. CrossrefGoogle Scholar

  • Kaya S., Cetin E.S., Aridoğan B.C.,ity of Blastocystis hominis, a clinical reevaluation. Türkiye Parazitoloji Derneği, 31, 184–187Google Scholar

  • Kurniawan A., Karyadi T., Dwintasari S.W., Sari I.P., Yunihastuti E., Djauzi S., Smith H.V. 2009. Intestinal parasitic infections in HIV/AIDS patients presenting with diarrhoea in Jakarta, Indonesia. Transactions of the Royal Society of Tropical Medicine and Hygiene, 103, 892–898. CrossrefGoogle Scholar

  • Lee M.G., Rawlins S.C., Didier M., Deceulaer K. 1990. Infective arthritis due to Blastocystis hominis. Annals of the Rheumatic Diseases, 49, 192–193. CrossrefGoogle Scholar

  • Li X.X., Chen J.X., Wang L.X., Tian L.G., Zhang Y.P., Dong S.P., et al. 2015 Prevalence and risk factors of intestinal protozoan and helminth infections among pulmonary tuberculosis patients without HIV infection in a rural country in P. R. China. Acta Tropica, 149, 19–26. CrossrefGoogle Scholar

  • Parija S.C., Khairnar K. 2005. Entamoeba moshkovskii and Entamoeba dispar-associated infections in Pondicherry, India. Journal of Health Population and Nutrition, 23, 292–295Google Scholar

  • Pasqui A.L., Savini E., Saletti M., Guzzo C., Puccetti L., Auteri A. 2004. Chronic urticaria and Blastocystis hominis infection. A case report. European Review for Medical and Pharmacological Sciences, 8, 117–120Google Scholar

  • Poirier P., Wawrzyniak I., Albert A., El Alaoui H., Delbac F., Livrelli V. 2011. Development and evaluation of a real-time PCR assay for detection and quantification of blastocystis parasites in human stool samples: prospective study of patients with hematological malignancies. Journal of Clinical Microbiology, 49, 975–983. CrossrefGoogle Scholar

  • Poulsen C.S., Stensvold Ch.R. 2016. Systematic review on Endolimax nana: A less well studied intestinal ameba. Tropical Parasitology, 6, 8–29. CrossrefGoogle Scholar

  • Rhongbutsri P., Saichua P., Navaphongpaveen K., Taylor A., Leelawongtawon R., Kitvatanachai S. 2010. Intestinal parasitic infections in students at a school for handicapped children in Khon Kaen Province, Thailand. Thammasat Medical Journal, 10, 406–410. CrossrefGoogle Scholar

  • Ritchie L.S. 1948. An ether sedimentation technique for routine stool examinations. Bulletin United States Army Medical Department, 8, 326Google Scholar

  • Sadaf H.S., Khan S.S., Urooj K.S., Asma B., Ajmal S.M. 2013. Blastocystis hominis – potential diahorreal agent: a review. International Research Journal of Pharmacy, 4, 1–5Google Scholar

  • Shah M., Tan C.B., Rajan D., Ahmed S., Subramani K., Rizvon K., Mustacchia P. 2012. Blastocystis hominis and Endolimax nana co-infection resulting in chronic diarrhea in an immunocompetent male. Case Reports in Gastroenterology, 6, 358–364. CrossrefGoogle Scholar

  • Sheehan D.J., Raucher B.G., McKitrick J.C. 1986. Association of Blastocystis hominis with signs and symptoms of human disease. Journal of Clinical Microbiology, 24, 548–550Google Scholar

  • Solaymani-Mohammadi S., Petri W.A. 2008. Intestinal invasion by Entamoeba histolytica. Subcellular Biochemistry, 47, 221– 232. CrossrefGoogle Scholar

  • Stanley S.L.Jr 2003. Amoebiasis. Lancet 361, 1025–1034. CrossrefGoogle Scholar

  • Stark D., Barratt J.L.N., van Hal S., Marriott D., Harkness J., Ellis J.T. 2009. Clinical Significance of Enteric Protozoa in the Immunosuppressed Human Population. Clinical Microbiology Reviews, 22, 634–650. CrossrefGoogle Scholar

  • Tamalee R., Ellis J., Harkness J., Marriott D., Stark D. 2014. Treatment failure in patients with chronic Blastocystis infection. Journal of Medical Microbiology, 63, 252–257. CrossrefGoogle Scholar

  • Tan T., Suresh K. 2006. Predominance of amoeboid forms of Blastocystis hominis in isolates from symptomatic patients. Parasitology Research, 98, 189–193. CrossrefGoogle Scholar

  • Tasova Y., Sahin B., Koltas S., Paydas S. 2000. Clinical significance and frequency of Blastocystis hominis in Turkish patients with hematological malignancy. Acta Medica Okayama, 54, 133– 136Google Scholar

  • Telalbasic S., Pikula Z.P., Kapidzic M. 1991. Blastocystis hominis may be a potential cause of intestinal disease. Scandinavian Journal of Infectious Diseases, 23, 389–390. CrossrefGoogle Scholar

  • Tolarová V. 1989. Recommended methods of laboratory diagnostics of tropical parasites. Acta hygienica, epidemiologica et microbiologica, Annex no. 12, 21–22Google Scholar

  • Wang W. 2014. Investigating the suitability of dogs and pigs as animal models for blastocystosis. PhD Thesis, University of Queensland, AustraliaGoogle Scholar

  • Weissman S.B., Salata R.A. 2000. Amebiasis. In: (Eds) R.E. Behrman, R.M. Kleiegman and B.H. Jenson Nelson Textbook of paediatrics. W. B. Saunders Company, Philadelphia, pp 1035–1036Google Scholar

  • Young C.R., Yeo F.E. 2014. Blastocystis and schistosomiasis coinfection in a patient with chronic kidney disease. Case Reports in Medicine. CrossrefGoogle Scholar

About the article

Received: 2017-09-11

Revised: 2018-08-23

Accepted: 2018-08-28

Published Online: 2018-10-18

Published in Print: 2018-12-19


Conflict of Interest. The authors declare that they have no conflict of interest.

Ethical approval. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.


Citation Information: Acta Parasitologica, Volume 63, Issue 4, Pages 819–825, ISSN (Online) 1896-1851, ISSN (Print) 1230-2821, DOI: https://doi.org/10.1515/ap-2018-0100.

Export Citation

© 2018 W. Stefański Institute of Parasitology, PAS.Get Permission

Comments (0)

Please log in or register to comment.
Log in