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Acta Parasitologica

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Volume 63, Issue 4


Meglumine antimoniate-induced DRESS: original case with a positive skin test

Amel Chaabane / Haifa Ben Romdhane / Hajer Ben Brahim / Nadia Ben Fredj / Zohra Chadli / Naceur A Boughattas / Mohamed Chakroun / Karim Aouam
Published Online: 2018-10-18 | DOI: https://doi.org/10.1515/ap-2018-0104


We report a case of a 64-year-old woman treated with meglumine antimoniate (Glucantime®). On day 20, she developed fever, a pruriginous skin rash and myalgia. The blood tests showed eosinophilia and hepatic cytolysis. The clinico-biological picture improved gradually and the symptoms disappeared 4 weeks after the drug withdrawal. Six weeks later, intradermal tests to Glucantime® were performed and were positive at 48 hour-reading. This clinical picture suggests DRESS induced by meglumine antimoniate. To the best of our knowledge, only one case of meglumine antimoniate-induced DRESS has been reported in the literature and we are the first to report a case confirmed by skin tests.

Keywords: meglumine antimoniate; drug rash with eosinophilia and systemic symptoms (DRESS); skin tests


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About the article

Received: 2017-11-23

Revised: 2018-05-19

Accepted: 2018-07-17

Published Online: 2018-10-18

Published in Print: 2018-12-19

Conflicts of interest. The authors declare no conflict of interest.

Citation Information: Acta Parasitologica, Volume 63, Issue 4, Pages 845–847, ISSN (Online) 1896-1851, ISSN (Print) 1230-2821, DOI: https://doi.org/10.1515/ap-2018-0104.

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