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Autex Research Journal

The Journal of Association of Universities for Textiles (AUTEX)


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Open Access
Online
ISSN
2300-0929
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Hemostatic, Resorbable Dressing of Natural Polymers-Hemoguard

Maria Wiśniewska-Wrona1 / Magdalena Kucharska1 / Marcin H. Struszczyk2 / Magdalena Cichecka2 / Bożena Wilbik-Hałgas2 / Maria Szymonowicz3 / Danuta Paluch3 / Krystyna Guzińska1 / Zbigniew Rybak3

1Institute of Biopolymers and Chemical Fibres, ul. M. Skłodowskiej-Curie 19/27, 90-570 Łódź

2Institute of Security Technologies „MORATEX”, ul. M. Skłodowskiej-Curie 3, 90-965 Łódź

3Department of Experimental Surgery and Biomaterials Research, Wroclaw Medical University, ul. Poniatowskiego 2, 50-326 Wrocław

© 2016 Autex Research Journal. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. (CC BY-NC-ND 3.0)

Citation Information: Autex Research Journal. Volume 16, Issue 1, Pages 29–34, ISSN (Online) 2300-0929, DOI: https://doi.org/10.1515/aut-2015-0051, April 2016

Publication History

Published Online:
2016-04-14

Abstract

Investigations are presented for the preparation of a model hemostatic dressing that would exhibit an adequate hemostatic capacity in injuries and surgical wounds, an antibacterial activity to prevent primary and secondary infections, and offer safety in use. The Hemoguard dressing has been designed as a powder prepared from the complex chitosan/alginate Na/Ca in the form of micro- and nano-fibrids. Useful antibacterial and hemostatic properties of Hemoguard, which would qualify the material as first aid dressing and a temporary protection of injury wounds in field conditions, were assessed. Biocompatibility of the dressing was confirmed by biological in vitro examinations.

Keywords: hemostatic; chitosan-alginate micro- and nano-fibrids; antibacterial activity

References

  • [1] Niekraszewicz A., Lebioda J., Kucharska M., Wesołowska E.; „Research into Developing Antibacterial Dressing Materials”, Fibres & Textiles in Eastern Europe, vol.15, No 1(60), (2007)

  • [2] Kucharska M., Niekraszewicz A., Lebioda J., Brzoza-Malczewska K., Wesołowska E., „Bioactive Composite Materials” monograph, vol. XII edited by M. Jaworska „Progress on Chemistry and Application of Chitin and Its Derivatives”, p.131-138, Polish Chitin Society, (2007)

  • [3] Niekraszewicz A., Kucharska M., Wawro D., Struszczyk M. H., Rogaczewska A.: “Development of a Manufacturing Method for Surgical Meshes Modified by Chitosan”, Fibres & Textiles in Eastern Europe, vol.15, No 3(62), (2007)

  • [4] Niekraszewicz A., Kucharska M., Wiśniewska-Wrona M., Kardas I.: „Biological and Physicochemical Study of the Implantation of a Modified Polyester Vascular Prosthesis”, Fibres & Textiles in Eastern Europe, vol. 18, No 6 (83), p. 100-105, (2010)

  • [5] Niekraszewicz A., Kucharska M., Kardas I., Wiśniewska-Wrona M., Kustosz R., Jarosz A.: „Chitosan Coatings to Seal Cardiovascular Prostheses”, Fibres & Textiles in Eastern Europe, vol. 19, No 3 (86), p. 106-111, (2011)

  • [6] Kucharska M., Ciechańska D., Niekraszewicz A., Wiśniewska–Wrona M., Kardas I.: “Potential use of chitosan–based materials in medicine”, „Progress on chemistry and application of chitin and its derivatives”, periodical, vol. XV, ed by M. Jaworska, Polish Chitin Society, Łódź, p.169-176, (2010)

  • [7] Wiśniewska-Wrona M., Kucharska M., Kardas I., Bodek A., Bodek K. H.: „ Polymer biocomposites used in bedsores treatment” „Progress on chemistry and application of chitin and its derivatives”, periodical, vol. XVI, ed. by M. Jaworska, Polish Chitin Society, Łódź, p.111-120, (2011)

  • [8] Kucharska M., Niekraszewicz A., Kardas I., Marcol W., Właszczuk A., Larysz-Brysz M., Lewin – Kowalik J.: “Developing a Model of Peripheral Nerve Graft Based on Natural Polymers”, Fibres & Textiles in Eastern Europe, vol. 20, No 6B (96), p. 115-120, (2012)

  • [9] Kucharska M., Struszczyk M. H., Cichecka M., Brzoza-Malczewska K., Wiśniewska-Wrona M.: “Prototypes of Primary Wound Dressing of fibrous and Quasi_fibrous Structure in Terms of Safety of Their Usage”, Fibres & Textiles in Eastern Europe, vol. 20, No 6B (96), p. 142-148, (2012)

  • [10] Wiśniewska-Wrona M., Niekraszewicz A., Struszczyk H.,. Guzińska G; „Estimation of Polymer Compositions Containing Chitosan for Veterinary Applications”, Fibres & Textiles in Eastern Europe, vol.10, No 3(38), (2002)

  • [11] PL 214 380 B1 (2008)

  • [12] PL 214 380 B1 (2008)

  • [13] PN-EN ISO 13726-1: 2005, Methods for the direct testing of wounds. Part 1: Aspects concerning absorption.

  • [14] PN-EN ISO 13726-2:2005, Methods for the direct testing of wounds. Part 2: Transmission of moisture through the dressing with a semi-permeable film” for model dressing.

  • [15] Procedure PB 1, Examination of antibacterial action of textile products. Quantitative test” prepared on base of JISL 1902:2002.

  • [16] ASTM, F 756 – 00, 2008, Standard practice for assessment of hemolytic properties of materials.

  • [17] PN EN ISO 10993-4: 2009, Biological evaluation of medical devices. Part 4: Selection of tests for interactions with blood.

  • [18] Szymonowicz M., Fraczek-Szczypta A., Rybak Z., Blazewicz S.: „Comparative assessment of the effect of carbon-based material surfaces on blood clotting activation and haemolysis”. Diamond & Related Materials, 2013, Vol. 40, 89-95.

  • [19] Szymonowicz M., Pielka S., Owczarek A, Haznar D., Pluta J.: “Study on influence of gelatin-alginate matrixes on the coagulation system and morphotic blood elements.” Macromolecular Symposia, 2007, Vol. 253, 71-76.

  • [20] Gadelha de Carvalho M.M.S., Montenegro Stamford T. C., Pereira dos Santos E., Tenório and F.Sampaio P.: “Chitosan as an oral antimicrobial agent”, Formatex 2011

  • [21] Yadav AV, Bhise .B.:” Chitosan: a potential biomaterial effective against typhoid.” Cur. Sci.87(9): 1176-1178, (2004)

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