Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Thomas, Douglas D. / Turk, Boris / Wittinghofer, Alfred


IMPACT FACTOR 2017: 3.022

CiteScore 2018: 3.09

SCImago Journal Rank (SJR) 2018: 1.482
Source Normalized Impact per Paper (SNIP) 2018: 0.820

Online
ISSN
1437-4315
See all formats and pricing
More options …
Volume 381, Issue 11

Issues

The in Vitro Phosphorylation of the Co-Chaperone mSTI1 by Cell Cycle Kinases Substantiates a Predicted Casein Kinase II-p34cdc2-NLS (CcN) Motif

V.M. Longshaw / H.W. Dirr / G.L. Blatch / M. Lässle
Published Online: 2005-07-05 | DOI: https://doi.org/10.1515/BC.2000.139

Abstract

The co-chaperone murine stress-inducible protein 1 (mSTI1), a Hsp70/Hsp90 organizing protein (Hop) homolog, functions as a physical link between Hsp70 and Hsp90 by mediating the formation of the mSTI1/ Hsp70/Hsp90 chaperone heterocomplex. We show here that mSTI1 is an in vitro substrate of cell cycle kinases. Casein kinase II (CKII) phosphorylates mSTI1 at S189, and cdc2 kinase (p34cdc2) at T198, substantiating a predicted CKII-p34cdc2-NLS (CcN) motif. The possible implications of this phosphorylation as a cell cycle checkpoint are discussed.

About the article

Published Online: 2005-07-05

Published in Print: 2000-11-15


Citation Information: Biological Chemistry, Volume 381, Issue 11, Pages 1133–1138, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/BC.2000.139.

Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

[1]
FLAVIO MEGGIO and LORENZO A. PINNA
The FASEB Journal, 2003, Volume 17, Number 3, Page 349
[2]
Rachel E. Lackie, Andrzej Maciejewski, Valeriy G. Ostapchenko, Jose Marques-Lopes, Wing-Yiu Choy, Martin L. Duennwald, Vania F. Prado, and Marco A. M. Prado
Frontiers in Neuroscience, 2017, Volume 11
[3]
Jingyu Li, Xiaodong Sun, Zaizhu Wang, Li Chen, Dengwen Li, Jun Zhou, Min Liu, and Paolo Madeddu
PLoS ONE, 2012, Volume 7, Number 4, Page e36389
[4]
Mehdi Mollapour and Len Neckers
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2012, Volume 1823, Number 3, Page 648
[5]
Grace W. Gitau, Pradipta Mandal, Gregory L. Blatch, Jude Przyborski, and Addmore Shonhai
Cell Stress and Chaperones, 2012, Volume 17, Number 2, Page 191
[6]
Viviane C.H. da Silva and Carlos H.I. Ramos
Journal of Proteomics, 2012, Volume 75, Number 10, Page 2790
[7]
Marta Stankiewicz, Rainer Nikolay, Vladimir Rybin, and Matthias P. Mayer
FEBS Journal, 2010, Volume 277, Number 16, Page 3353
[8]
Sheril Daniel, Graeme Bradley, Victoria M. Longshaw, Csaba Söti, Peter Csermely, and Gregory L. Blatch
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008, Volume 1783, Number 6, Page 1003
[9]
Akikazu Sakudo, Deug-chan Lee, Shuming Li, Toyoo Nakamura, Yoshitsugu Matsumoto, Keiichi Saeki, Shigeyoshi Itohara, Kazuyoshi Ikuta, and Takashi Onodera
Biochemical and Biophysical Research Communications, 2005, Volume 328, Number 1, Page 14
[10]
Bradley T Scroggins and Len Neckers
Expert Opinion on Drug Discovery, 2007, Volume 2, Number 10, Page 1403
[11]
Sebastian K Wandinger, Michael H Suhre, Harald Wegele, and Johannes Buchner
The EMBO Journal, 2006, Volume 25, Number 2, Page 367
[12]
O.O. Odunuga, V.M. Longshaw, and G.L. Blatch
BioEssays, 2004, Volume 26, Number 10, Page 1058

Comments (0)

Please log in or register to comment.
Log in