Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Thomas, Douglas D. / Turk, Boris / Wittinghofer, Alfred

IMPACT FACTOR 2018: 3.014
5-year IMPACT FACTOR: 3.162

CiteScore 2018: 3.09

SCImago Journal Rank (SJR) 2018: 1.482
Source Normalized Impact per Paper (SNIP) 2018: 0.820

See all formats and pricing
More options …
Volume 381, Issue 8


IAA-Synthase, an Enzyme Complex from Arabidopsis thaliana Catalyzing the Formation of Indole-3-Acetic Acid from (S)-Tryptophan

A. Müller / E.W. Weiler
Published Online: 2005-07-05 | DOI: https://doi.org/10.1515/BC.2000.088


An enzyme complex was isolated from Arabidopsis thaliana that catalyzes the entire pathway of biosynthesis of the major plant growth hormone, indole-3-acetic acid (IAA), from (S)-tryptophan. The 160–180 kDa, soluble complex catalyzes a strictly O2-dependent reaction which requires no further added factors and is stereospecific for the substrate (S)-tryptophan (app. Km = 120μM). H2 18O labeling proved that both oxygen atoms of IAA were delivered via H2O. This, as well as immunological evidence for the presence of a nitrilase-like protein in the complex, suggests the reaction to proceed via the intermediate indole-3-acetonitrile. IAA-synthase forms a tight metabolite channel committed to IAA production and occurs in shoots, roots and cell cultures of A. thaliana.

About the article

Published Online: 2005-07-05

Published in Print: 2000-08-06

Citation Information: Biological Chemistry, Volume 381, Issue 8, Pages 679–686, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/BC.2000.088.

Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Jun Zhang, Jinshan Ella Lin, Chinchu Harris, Fernanda Campos Mastrotti Pereira, Fan Wu, Joshua J. Blakeslee, and Wendy Ann Peer
Proceedings of the National Academy of Sciences, 2016, Volume 113, Number 39, Page 11010
Beatriz Sánchez-Parra, Henning Frerigmann, Marta-Marina Alonso, Víctor Loba, Ricarda Jost, Mathias Hentrich, and Stephan Pollmann
Plants, 2014, Volume 3, Number 3, Page 324
Catarina Henke, Elke-Martina Jung, Annekatrin Voit, Erika Kothe, and Katrin Krause
Journal of Basic Microbiology, 2016, Volume 56, Number 2, Page 162
Chris Hawes, Petra Kiviniemi, and Verena Kriechbaumer
Journal of Integrative Plant Biology, 2015, Volume 57, Number 1, Page 50
C. Singleton, T. P. Howard, and N. Smirnoff
Journal of Experimental Botany, 2014, Volume 65, Number 8, Page 1947
Verena Kriechbaumer, Pengwei Wang, Chris Hawes, and Ben M. Abell
The Plant Journal, 2012, Volume 70, Number 2, Page 292
Heather Nonhebel, Youxi Yuan, Hussein Al-Amier, Michael Pieck, Enne Akor, Arifa Ahamed, Jerry D. Cohen, John L. Celenza, and Jennifer Normanly
Phytochemistry, 2011, Volume 72, Number 1, Page 37
John L Celenza
Current Opinion in Plant Biology, 2001, Volume 4, Number 3, Page 234
Jerry D. Cohen, Janet P. Slovin, and Angela M. Hendrickson
Trends in Plant Science, 2003, Volume 8, Number 5, Page 197
Michael Rothballer, Barbara Eckert, Michael Schmid, Agnes Fekete, Michael Schloter, Angelika Lehner, Stephan Pollmann, and Anton Hartmann
FEMS Microbiology Ecology, 2008, Volume 66, Number 1, Page 85
Sugihiro Ando, Seiya Tsushima, Shinichiro Kamachi, Ken-ichi Konagaya, and Yutaka Tabei
Plant Molecular Biology, 2008, Volume 68, Number 6, Page 557
S. Pollmann, A. Müller, and E. W. Weiler
Plant Biology, 2006, Volume 8, Number 3, Page 326
V. Kriechbaumer, W. J. Park, A. Gierl, and E. Glawischnig
Plant Biology, 2006, Volume 8, Number 3, Page 334
Stephan Pollmann, Daniel Neu, Thomas Lehmann, Oliver Berkowitz, Tina Schäfer, and Elmar W. Weiler
Planta, 2006, Volume 224, Number 6, Page 1241
Alexandra Kutz, Axel Muller, Peter Hennig, Werner M. Kaiser, Markus Piotrowski, and Elmar W. Weiler
The Plant Journal, 2002, Volume 30, Number 1, Page 95
C. O'Reilly and P.D. Turner
Journal of Applied Microbiology, 2003, Volume 95, Number 6, Page 1161

Comments (0)

Please log in or register to comment.
Log in