Jump to ContentJump to Main Navigation
Show Summary Details

Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board Member: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Sies, Helmut / Turk, Boris / Wittinghofer, Alfred

12 Issues per year

IMPACT FACTOR 2015: 2.710
Rank 142 out of 289 in category Biochemistry & Molecular Biology in the 2015 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2015: 1.607
Source Normalized Impact per Paper (SNIP) 2015: 0.751
Impact per Publication (IPP) 2015: 2.609

See all formats and pricing
Volume 382, Issue 3 (Mar 2001)


Localization of Lysobisphosphatidic Acid-Rich Membrane Domains in Late Endosomes

Toshihide Kobayashi / Konstantin Startchev / Andrew J. Whitney / Jean Gruenberg
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/BC.2001.059


Late endosomes accumulate internal membranes within the lumen of the organelle. These internal membranes are enriched in the late endosome specific phospholipid, lysobisphosphatidic acid (LBPA). The organization of LBPArich membrane domains is not well characterized. Using an LBPAspecific monoclonal antibody (6C4), we show that these membrane domains are not accessible from the cytoplasm. Using fluorescence correlation spectroscopy, we also show that 6C4 only binds sonicated, but not intact, late endosomes, presumably reflecting the release of internal membranes upon endosome rupture.

About the article

Published Online: 2005-06-01

Published in Print: 2001-03-21

Citation Information: Biological Chemistry, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/BC.2001.059. Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Romain Galmes, Corlinda ten Brink, Viola Oorschot, Tineke Veenendaal, Caspar Jonker, Peter van der Sluijs, and Judith Klumperman
Traffic, 2015, Page n/a
Zeynep Akgoc, Sonia Iosim, and Thomas N. Seyfried
Lipids, 2015
Jean Gruenberg
Nature Reviews Molecular Cell Biology, 2001, Volume 2, Number 10, Page 721
Skye Zeller, Chang Seon Choi, Pradeep D. Uchil, Hong-Seok Ban, Alyssa Siefert, Tarek M. Fahmy, Walther Mothes, Sang-Kyung Lee, and Priti Kumar
Chemistry & Biology, 2015, Volume 22, Number 1, Page 50
Barry Boland and Frances M. Platt
Best Practice & Research Clinical Endocrinology & Metabolism, 2015, Volume 29, Number 2, Page 127
Françoise Hullin-Matsuda, Tomohiko Taguchi, Peter Greimel, and Toshihide Kobayashi
Seminars in Cell & Developmental Biology, 2014, Volume 31, Page 48
Alfredo Erazo-Oliveras, Nandhini Muthukrishnan, Ryan Baker, Ting-Yi Wang, and Jean-Philippe Pellois
Pharmaceuticals, 2012, Volume 5, Number 12, Page 1177
Maaike S. Pols, Corlinda ten Brink, Prajakta Gosavi, Viola Oorschot, and Judith Klumperman
Traffic, 2013, Volume 14, Number 2, Page 219
G. Dawson, M. Fuller, K. M. Helmsley, and J. J. Hopwood
Neurochemical Research, 2012, Volume 37, Number 6, Page 1372
Sung-Tae Yang, Elena Zaitseva, Leonid V. Chernomordik, and Kamran Melikov
Biophysical Journal, 2010, Volume 99, Number 8, Page 2525
Hui-Hui Tan, Asami Makino, Kumar Sudesh, Peter Greimel, and Toshihide Kobayashi
Angewandte Chemie, 2012, Volume 124, Number 2, Page 548
Malgorzata E. Sztolsztener, Agnieszka Dobrzyn, Slawomir Pikula, Anna Tylki-Szymanska, and Joanna Bandorowicz-Pikula
Molecular BioSystems, 2012, Volume 8, Number 4, Page 1197
Thomas E. Frederick, Philip C. Goff, Chad E. Mair, R. Suzanne Farver, Joanna R. Long, and Gail E. Fanucci
Chemistry and Physics of Lipids, 2010, Volume 163, Number 7, Page 703
Anne M. Cataldo, Paul M. Mathews, Anne Boyer Boiteau, Linda C. Hassinger, Corrinne M. Peterhoff, Ying Jiang, Kerry Mullaney, Rachael L. Neve, Jean Gruenberg, and Ralph A. Nixon
The American Journal of Pathology, 2008, Volume 173, Number 2, Page 370
Nathalie Chaput and Clotilde Théry
Seminars in Immunopathology, 2011, Volume 33, Number 5, Page 419
F. Hullin-Matsuda, C. Luquain-Costaz, J. Bouvier, and I. Delton-Vandenbroucke
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2009, Volume 81, Number 5-6, Page 313
Tuanlao Wang and Wanjin Hong
Biochemical and Biophysical Research Communications, 2006, Volume 350, Number 2, Page 413
Lavinia Bhatt, Conor P. Horgan, and Mary W. McCaffrey
Biochemical and Biophysical Research Communications, 2009, Volume 378, Number 4, Page 727
Owen Pornillos, Jennifer E Garrus, and Wesley I Sundquist
Trends in Cell Biology, 2002, Volume 12, Number 12, Page 569
Tony Yeung, Barish Ozdamar, Paul Paroutis, and Sergio Grinstein
Current Opinion in Cell Biology, 2006, Volume 18, Number 4, Page 429
Fiona Fernandes, Kang Chen, Lorna S. Ehrlich, Jing Jin, Min H. Chen, Gisselle N. Medina, Marc Symons, Ronald Montelaro, Julie Donaldson, Nico Tjandra, and Carol A. Carter
Traffic, 2011, Volume 12, Number 4, Page 438
Steffen Bade, Andreas Rummel, Clemens Reisinger, Tino Karnath, Gudrun Ahnert-Hilger, Hans Bigalke, and Thomas Binz
Journal of Neurochemistry, 2004, Volume 91, Number 6, Page 1461
Serhiy Havrylov, Fumitaka Ichioka, Kate Powell, Emma B. Borthwick, Jolanta Baranska, Masatoshi Maki, and Vladimir L. Buchman
Traffic, 2008, Volume 9, Number 5, Page 798
Nelly Besson, Francoise Hullin-Matsuda, Asami Makino, Motohide Murate, Michel Lagarde, Jean-Francois Pageaux, Toshihide Kobayashi, and Isabelle Delton-Vandenbroucke
Lipids, 2006, Volume 41, Number 2, Page 189

Comments (0)

Please log in or register to comment.
Log in