Jump to ContentJump to Main Navigation
Show Summary Details

Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board Member: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Sies, Helmut / Turk, Boris / Wittinghofer, Alfred

SCImago Journal Rank (SJR) 2015: 1.607
Source Normalized Impact per Paper (SNIP) 2015: 0.751
Impact per Publication (IPP) 2015: 2.609

See all formats and pricing



Select Volume and Issue


Differential Haemoglobin Gene Expression in the Crustacean Daphnia magna Exposed to Different Oxygen Partial Pressures

B. Zeis / B. Becher / T. Goldmann / R. Clark / E. Vollmer / B. Bölke / I. Bredebusch / T. Lamkemeyer / O. Pinkhaus / R. Pirow / R. J. Paul

Citation Information: Biological Chemistry. Volume 384, Issue 8, Pages 1133–1145, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/BC.2003.126, June 2005

Publication History

Published Online:


The quantity and quality of the haemoglobin (Hb) of Daphnia magna is related to oxygen partial pressure in the water. Both the dynamics of hypoxia-induced Hb gene transcription, as well as Hb properties in animals incubated long-term at hyperoxia, normoxia and hypoxia, were investigated. Examination of Hb gene (dhb1-dhb3) transcription showed the expression of dhb2 and especially dhb3 to increase markedly approximately one hour after the onset of hypoxia, whereas dhb1 was expressed more or less constitutively. At an incubation close to anoxia, an onset of dhb3 transcription was found already after two minutes. In longterm incubated animals, concentration and oxygen affinity of Hb were lower at higher oxygen partial pressures. With decreasing oxygen availability, the subunit composition of Hb macromolecules changed. The share of the dhb2-encoded subunit, DHbF, increased already during moderate hypoxia. The increase of dhb3 mRNA (encoding DHbC) may be related to a transient increase of DHbC in the first days of hypoxia and/or to an additional coding of dhb3 for DHbD. The rise of DHbD, and particularly DHbA, only at severe hypoxia coincided with the increase of Hb oxygen affinity. The dhb1-encoded subunits DHbB and DHbE showed either a relatively moderate increase or even a decrease in concentration at hypoxia. In small animals with restricted homeostasis capabilities such as Daphnia, adaptation of the protein equipment seems to be a more effective strategy than allosteric modulator control.

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Thorsten Burmester
Integrative and Comparative Biology, 2015, Page icv079
Linda C. Weiss, Christian Laforsch, Ioanna Ioannidou, Zsofia Herbert, and Ralph Tollrian
Neuropeptides, 2014, Volume 48, Number 5, Page 287
R.J. Paul, T. Lamkemeyer, J. Maurer, O. Pinkhaus, R. Pirow, M. Seidl, and B. Zeis
Journal of Thermal Biology, 2004, Volume 29, Number 7-8, Page 655
Susan L. Carney, Jason F. Flores, Kathryn M. Orobona, David A. Butterfield, Charles R. Fisher, and Stephen W. Schaeffer
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2007, Volume 146, Number 3, Page 326
Bettina Zeis, Tobias Lamkemeyer, and Rüdiger J Paul
Micron, 2004, Volume 35, Number 1-2, Page 47
J.M. Head
Journal of Experimental Marine Biology and Ecology, 2010, Volume 386, Number 1-2, Page 77
Peter Gerke, Christina Börding, Bettina Zeis, and Rüdiger J. Paul
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2011, Volume 159, Number 1, Page 56
Ying H. Wang, Guirong Wang, and Gerald A. LeBlanc
General and Comparative Endocrinology, 2007, Volume 150, Number 2, Page 309
Bethany R. Hannas and Gerald A. LeBlanc
Molecular and Cellular Endocrinology, 2010, Volume 315, Number 1-2, Page 208
Bettina Zeis, Jana Maurer, Olaf Pinkhaus, Eva Bongartz, and Rüdiger J Paul
Canadian Journal of Zoology, 2004, Volume 82, Number 10, Page 1605
M.D. Seidl, R. Pirow, and R.J. Paul
Journal of Thermal Biology, 2005, Volume 30, Number 7, Page 532
Tobias Lamkemeyer, Rüdiger J. Paul, Walter Stöcker, Irene Yiallouros, and Bettina Zeis
Biological Chemistry, 2005, Volume 386, Number 11
Morgane Rousselot, Elmar Jaenicke, Tobias Lamkemeyer, J. Robin Harris, and Ralph Pirow
FEBS Journal, 2006, Volume 273, Number 17, Page 4055
B D Eads, J Andrews, and J K Colbourne
Heredity, 2008, Volume 100, Number 2, Page 184
Tobias Lamkemeyer, Bettina Zeis, Heinz Decker, Elmar Jaenicke, Dieter Waschbusch, Wolfgang Gebauer, Jurgen Markl, Ulrich Meissner, Morgane Rousselot, Franck Zal, Graeme J. Nicholson, and Rudiger J. Paul
FEBS Journal, 2006, Volume 273, Number 14, Page 3393
Frank NUNES, Désirée SPIERING, Marc WOLF, Alexandra WENDLER, Ralph PIROW, and Rüdiger J. PAUL
Bioscience, Biotechnology and Biochemistry, 2005, Volume 69, Number 6, Page 1193

Comments (0)

Please log in or register to comment.