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Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

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Volume 387, Issue 6 (Jun 2006)


A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

Åke Lundwall
  • Lund University, Clinical Chemistry, Department of Laboratory Medicine, University Hospital MAS, S-205 02 Malmö, Sweden
/ Vimla Band
  • Department of Medicine, Evanston Northwestern Healthcare Research Institute, Evanston, IL 60201, USA
/ Michael Blaber
  • Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL 32306-4300, USA
/ Judith A. Clements
  • School of Life Sciences and Science Research Center, Queensland University of Technology, Brisbane, QLD 4001, Australia
/ Yves Courty
  • INSERM, U618, Protéases et Vectorisation Pulmonaires, Universite Francois Rabelais, F-37000 Tours, France
/ Eleftherios P. Diamandis
  • Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON M5G1X5, Canada
/ Hans Fritz
  • Division of Clinical Biochemistry at the Surgical Department City of the Ludwigs Maximilians University, D-80336 Munich, Germany
/ Hans Lilja
  • Departments of Clinical Laboratories, Urology, and Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
/ Johan Malm
  • Lund University, Clinical Chemistry, Department of Laboratory Medicine, University Hospital MAS, S-205 02 Malmö, Sweden
/ Lois J. Maltais
  • Mouse Genomic Nomenclature Committee (MGNC), Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
/ A. Yvonne Olsson
  • Molecular Carcinogenesis, Institute of Cancer Research, Sutton SM2 5NG, UK
/ Constantina Petraki
  • Department of Pathology, Evangelismos Hospital, GR-11364 Athens, Greece
/ Andreas Scorilas
  • Department of Biochemistry and Molecular Biology, University of Athens, GR-15701, Panepistimiopolis, Athens, Greece
/ Georgia Sotiropoulou
  • Department of Pharmacy, School of Health Sciences, University of Patras, GR-26500 Rion-Patras, Greece
/ Ulf-Håkan Stenman
  • Department of Clinical Chemistry, Helsinki University Central Hospital, FIN-00029 Helsinki, Finland
/ Carsten Stephan
  • Department of Urology, Universitätsmedizin Charité, Campus Mitte, D-10098 Berlin, Germany
/ Maroulio Talieri
  • G. Papanicolaou Research Center of Oncology, Saint Savas Hospital, GR-11522 Athens, Greece
/ George M. Yousef
  • Discipline of Pathology, Health Science Corporation of St. John's, St. John's, NF A1B 3V6, Canada
Published Online: 2006-06-26 | DOI: https://doi.org/10.1515/BC.2006.082


The human kallikrein locus on chromosome 19q13.3–13.4 contains kallikrein 1 – the tissue kallikrein – and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.

Keywords: cancer; evolution; hormone; inflammation; kininogen


About the article

Corresponding author

Published Online: 2006-06-26

Published in Print: 2006-06-01

Citation Information: Biological Chemistry, ISSN (Online) 1437-4315, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/BC.2006.082. Export Citation

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