Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Sies, Helmut / Thomas, Douglas D. / Turk, Boris / Wittinghofer, Alfred

12 Issues per year

IMPACT FACTOR 2017: 3.022

CiteScore 2017: 2.81

SCImago Journal Rank (SJR) 2017: 1.562
Source Normalized Impact per Paper (SNIP) 2017: 0.705

See all formats and pricing
More options …
Volume 388, Issue 9


Molecular machinery of mitochondrial dynamics in yeast

Sandra Merz / Miriam Hammermeister / Katrin Altmann / Mark Dürr / Benedikt Westermann
  • 5Institut für Zellbiologie, Universität Bayreuth, D-95440 Bayreuth, Germany and Bayreuther Zentrum für Molekulare Biowissenschaften, Universität Bayreuth, D-95440 Bayreuth, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2007-08-14 | DOI: https://doi.org/10.1515/BC.2007.110


Mitochondria are amazingly dynamic organelles. They continuously move along cytoskeletal tracks and frequently fuse and divide. These processes are important for maintenance of mitochondrial functions, for inheritance of the organelles upon cell division, for cellular differentiation and for apoptosis. As the machinery of mitochondrial behavior has been highly conserved during evolution, it can be studied in simple model organisms, such as yeast. During the past decade, several key components of mitochondrial dynamics have been identified and functionally characterized in Saccharomyces cerevisiae. These include the mitochondrial fusion and fission machineries and proteins required for maintenance of tubular shape and mitochondrial motility. Taken together, these findings reveal a comprehensive picture that shows the cellular processes and molecular components required for mitochondrial inheritance and morphogenesis in a simple eukaryotic cell.

Keywords: actin cytoskeleton; membrane division; membrane fusion; mitochondria; organelle biogenesis; Saccharomyces cerevisiae

About the article

Corresponding author

Published Online: 2007-08-14

Published in Print: 2007-09-01

Citation Information: Biological Chemistry, Volume 388, Issue 9, Pages 917–926, ISSN (Online) 14374315, ISSN (Print) 14316730, DOI: https://doi.org/10.1515/BC.2007.110.

Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Abdelouahid El-Khattouti, Denis Selimovic, Youssef Haikel, and Mohamed Hassan
Journal of Cell Death, 2013, Volume 6, Page JCD.S11034
Benedikt Westermann
Journal of Biological Chemistry, 2008, Volume 283, Number 20, Page 13501
Wen-Chih Cheng, Kelly M. Leach, and J. Marie Hardwick
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008, Volume 1783, Number 7, Page 1272
Danny V. Jeyaraju, Giulia Cisbani, and Luca Pellegrini
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2009, Volume 1787, Number 11, Page 1363
Dominik Bernhardt, Andrea Hamann, and Heinz D Osiewacz
Current Opinion in Microbiology, 2014, Volume 22, Page 1
Benedikt Westermann
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2014, Volume 1837, Number 7, Page 1039
Jin-Sook Lee, Xia Hou, Nicole Bishop, Sunxi Wang, Amanda Flack, Won Jin Cho, Xuequn Chen, Guangzhao Mao, Douglas J. Taatjes, Fei Sun, Kezhong Zhang, and Bhanu P. Jena
Micron, 2013, Volume 47, Page 50
Ralf J. Braun and Benedikt Westermann
Biochemical Society Transactions, 2011, Volume 39, Number 5, Page 1520
Benedikt Westermann
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2012, Volume 1817, Number 10, Page 1833
Benedikt Westermann
Current Biology, 2011, Volume 21, Number 22, Page R922
Arezu Jahani-Asl, Marc Germain, and Ruth S. Slack
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2010, Volume 1802, Number 1, Page 162
Johannes Förtsch, Eric Hummel, Melanie Krist, and Benedikt Westermann
The Journal of Cell Biology, 2011, Volume 194, Number 3, Page 473
Jian Zhao, Tong Liu, Shaobo Jin, Xinming Wang, Mingqi Qu, Per Uhlén, Nikolay Tomilin, Oleg Shupliakov, Urban Lendahl, and Monica Nistér
The EMBO Journal, 2011, Volume 30, Number 14, Page 2762
Hiroyoshi Takano, Kenta Onoue, and Shigeyuki Kawano
Journal of Plant Research, 2010, Volume 123, Number 2, Page 131
Christof Osman, Mathias Haag, Christoph Potting, Jonathan Rodenfels, Phat Vinh Dip, Felix T. Wieland, Britta Brügger, Benedikt Westermann, and Thomas Langer
The Journal of Cell Biology, 2009, Volume 184, Number 4, Page 583
Hiroshi Kitagaki
Biotechnology and Applied Biochemistry, 2009, Volume 53, Number 3, Page 145
Susanne M. Rafelski and Wallace F. Marshall
Nature Reviews Molecular Cell Biology, 2008, Volume 9, Number 8, Page 593
Yeast, 2008, Volume 25, Number 5, Page 377
Katrin Altmann, Martina Frank, Daniel Neumann, Stefan Jakobs, and Benedikt Westermann
The Journal of Cell Biology, 2008, Volume 181, Number 1, Page 119

Comments (0)

Please log in or register to comment.
Log in