Jump to ContentJump to Main Navigation
Show Summary Details
In This Section

Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board Member: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Sies, Helmut / Thomas, Douglas D. / Turk, Boris / Wittinghofer, Alfred

12 Issues per year


IMPACT FACTOR 2016: 3.273

CiteScore 2016: 3.01

SCImago Journal Rank (SJR) 2015: 1.607
Source Normalized Impact per Paper (SNIP) 2015: 0.751

Online
ISSN
1437-4315
See all formats and pricing
In This Section
Volume 393, Issue 11 (Nov 2012)

Issues

Structure and function of bacterial dynamin-like proteins

Marc Bramkamp
  • Corresponding author
  • Ludwig-Maximilians-University Munich, Biocenter, Department Biology I, Großhaderner Str. 2-4, D-82152 Planegg-Martinsried, Germany
  • University of Cologne, Department of Chemistry, Institute of Biochemistry, Zülpicher Str. 47, D-50674 Cologne, Germany
  • Email:
Published Online: 2012-10-11 | DOI: https://doi.org/10.1515/hsz-2012-0185

Abstract

Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis to membrane deformation, which eventually leads to fusion or fission of the lipid bilayer. Mutations in eukaryotic dynamin-like proteins (DLPs) are associated with various diseases underscoring the importance to fully understand the biochemistry of these proteins. In recent years, a wealth of structural and biochemical data have been published that allow a detailed analysis of how dynamins or DLPs modulate biological membranes. However, less is known about the function of bacterial DLPs, although structural data exist. This review summarizes current knowledge about bacterial dynamins and discusses structural and functional properties in comparison to their eukaryotic counterparts.

Keywords: BDLP; cytokinesis; DynA; dynamin; fission; fusion; GTPase, membrane

About the article

Corresponding author: Marc Bramkamp, Ludwig-Maximilians-University Munich, Biocenter, Department Biology I, Großhaderner Str. 2-4, D-82152 Planegg-Martinsried, Germany; and University of Cologne, Department of Chemistry, Institute of Biochemistry, Zülpicher Str. 47, D-50674 Cologne, Germany


Received: 2012-04-23

Accepted: 2012-06-29

Published Online: 2012-10-11

Published in Print: 2012-11-01


Citation Information: , ISSN (Online) 1437-4315, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/hsz-2012-0185.

Export Citation

©2012 by Walter de Gruyter Berlin Boston. Copyright Clearance Center

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

[2]
Katherine Labbé, Andrew Murley, and Jodi Nunnari
Annual Review of Cell and Developmental Biology, 2014, Volume 30, Number 1, Page 357
[3]
Felix Dempwolff and Peter L Graumann
Communicative & Integrative Biology, 2014, Volume 7, Number 5, Page 1
[4]
John A. Fuerst and Evgeny Sagulenko
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014, Volume 1843, Number 8, Page 1732
[5]
Shogo Ozaki, Yusaku Matsuda, Kenji Keyamura, Hironori Kawakami, Yasunori Noguchi, Kazutoshi Kasho, Komomo Nagata, Tamami Masuda, Yukari Sakiyama, and Tsutomu Katayama
Cell Reports, 2013, Volume 4, Number 5, Page 985
[6]
V. Lila Koumandou, Bill Wickstead, Michael L. Ginger, Mark van der Giezen, Joel B. Dacks, and Mark C. Field
Critical Reviews in Biochemistry and Molecular Biology, 2013, Volume 48, Number 4, Page 373
[7]
Lisa N. Kinch and Nick V. Grishin
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2013, Volume 1828, Number 12, Page 2937

Comments (0)

Please log in or register to comment.
Log in