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Publicly Available Published by De Gruyter August 1, 2012

Methylation – an uncommon modification of glycans

  • Erika Staudacher

    Dr. Erika Staudacher, Associate Professor for biochemistry at the Department of Chemistry, University of Natural Resources and Life Sciences Vienna, Austria. Her research interest is the glycosylation of invertebrates. Starting in the early 1990s with insect glycan analysis and glycosyltransferase determination, her main focus is now the glycosylation abilities of gastropods. In 2011 she co-organized the XXIst International Conference on Glycoconjugates (Glyco21) in Vienna.

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From the journal Biological Chemistry

Abstract

A methyl (Me) group on a sugar residue is a rarely reported event. Until now, this type of modification has been found in the animal kingdom only in worms and molluscs, whereas it is more frequently present in some species of bacteria, fungi, algae and plants, but not in mammals. The monosaccharides involved as well as the positions of the Me groups on the sugar vary with species. Methylation appears to play a role in some recognition events, but details are still unknown. This review summarises the current knowledge on methylation of sugars in all types of organism.

About the author

Erika Staudacher

Dr. Erika Staudacher, Associate Professor for biochemistry at the Department of Chemistry, University of Natural Resources and Life Sciences Vienna, Austria. Her research interest is the glycosylation of invertebrates. Starting in the early 1990s with insect glycan analysis and glycosyltransferase determination, her main focus is now the glycosylation abilities of gastropods. In 2011 she co-organized the XXIst International Conference on Glycoconjugates (Glyco21) in Vienna.

Received: 2012-2-27
Accepted: 2012-3-27
Published Online: 2012-08-01
Published in Print: 2012-08-01

©2012 by Walter de Gruyter Berlin Boston

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