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Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Thomas, Douglas D. / Turk, Boris / Wittinghofer, Alfred


IMPACT FACTOR 2018: 3.014
5-year IMPACT FACTOR: 3.162

CiteScore 2018: 3.09

SCImago Journal Rank (SJR) 2018: 1.482
Source Normalized Impact per Paper (SNIP) 2018: 0.820

Online
ISSN
1437-4315
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Volume 393, Issue 9

Issues

Redox Biology on the rise

Johannes M. Herrmann
  • Zellbiologie, Technische Universität Kaiserslautern, Erwin-Schrödinger-Str. 13, D-67663 Kaiserslautern, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Tobias P. Dick
  • Corresponding author
  • Division of Redox Regulation, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar

Abstract

Redox reactions are at the heart of bioenergetics, yet their biological role is not restricted to metabolism. One specific focus of contemporary Redox Biology is the study of how the folding, stability, activity, and interactivity of proteins are subject to redox control. Key questions pertain to the chemical nature of physiological redox changes and their exact location inside the cell, the nature and distribution of protein redox modifications, and their meaning for cellular physiology. In recent years, Redox Biology has developed novel methodological directions, for example, the proteomic profiling of protein redox modifications and the noninvasive monitoring of redox processes in vivo. These and other approaches allow asking new questions for which the answers are almost completely unknown. To stimulate exchange of technical knowledge and the appreciation of Redox Biology in general, the German Society for Biochemistry and Molecular Biology (GBM) recently founded a Study Group for Redox Biology.

Keywords: Redox Biology; redox regulation; thiol oxidation

About the article

Corresponding author


Received: 2012-01-27

Accepted: 2012-05-11

Published in Print: 2012-09-01


Citation Information: , Volume 393, Issue 9, Pages 999–1004, ISSN (Online) 1437-4315, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/hsz-2012-0111.

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©2012 by Walter de Gruyter Berlin Boston.Get Permission©[year] by Walter de Gruyter Berlin Boston.Get Permission

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