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Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board: Buchner, Johannes / Lei, Ming / Ludwig, Stephan / Thomas, Douglas D. / Turk, Boris / Wittinghofer, Alfred

IMPACT FACTOR 2017: 3.022

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Volume 397, Issue 3


How to build the fastest receptor on earth

Jelena Baranovic
  • Leibniz Institut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, D-13125 Berlin, Germany
  • NeuroCure, Charité-Universitätsmedizin, Charitéplatz 1, D-10117, Berlin, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Andrew J.R. PlestedORCID iD: http://orcid.org/0000-0001-6062-0832
Published Online: 2015-08-31 | DOI: https://doi.org/10.1515/hsz-2015-0182


In 2014, a slew of structures of glutamate receptors were published, based on crystallography and electron microscopy. Here we review these insights, integrate them with existing knowledge about receptor function and try to understand how the structures relate to the key property of the AMPA receptor – its speed.

Keywords: AMPA receptors; functional properties; structural biology


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About the article

Corresponding author: Andrew J.R. Plested, Leibniz Institut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, D-13125 Berlin, Germany; and NeuroCure, Charité-Universitätsmedizin, Charitéplatz 1, D-10117, Berlin, Germany, e-mail: .

Received: 2015-05-23

Accepted: 2015-08-27

Published Online: 2015-08-31

Published in Print: 2016-03-01

Citation Information: Biological Chemistry, Volume 397, Issue 3, Pages 195–205, ISSN (Online) 1437-4315, ISSN (Print) 1431-6730, DOI: https://doi.org/10.1515/hsz-2015-0182.

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