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Biomedical Glasses

Editor-in-Chief: Boccaccini, Aldo R.

CiteScore 2018: 2.05

SCImago Journal Rank (SJR) 2018: 0.424
Source Normalized Impact per Paper (SNIP) 2018: 0.562

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Sodium-free mixed alkali bioactive glasses

Delia S. Brauer
  • Corresponding author
  • Otto Schott Institute of Materials Research, Friedrich Schiller University Jena, Fraunhoferstr. 6, 07743 Jena, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Raika Brückner
  • Corresponding author
  • Otto Schott Institute of Materials Research, Friedrich Schiller University Jena, Fraunhoferstr. 6, 07743 Jena, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Maxi Tylkowski
  • Corresponding author
  • Otto Schott Institute of Materials Research, Friedrich Schiller University Jena, Fraunhoferstr. 6, 07743 Jena, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Leena Hupa
  • Corresponding author
  • Johan Gadolin Process Chemistry Centre, Åbo Akademi University, Piispankatu 8, FI-20500 Turku, Finland
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2016-12-14 | DOI: https://doi.org/10.1515/bglass-2016-0012


Two sodium-free mixed alkali series of bioactive glasses based on compositions Bioglass 45S5 and ICIE1, containing lithium and/or potassium as alkali ions, were prepared by a melt-quench route. Thermal properties showed the well-known mixed alkali effect, with glass transition and crystallisation temperatures and the coefficient of thermal expansion going either through a minimum or a maximum for the mixed alkali composition, resulting in a wider processing window. Ion release, by contrast, was controlled by the modifier ionic radius, with ion release rates in dynamic and static dissolution studies increasing for potassium-substituted glasses compared to the composition containing lithium as the only alkali ion. This was caused by pronounced changes in oxygen packing density and molar volume of the glasses owing to the differences in ionic radii (76 pm for Li+ and 138 pm for K+). Partially substituting one alkali for another therefore helps to improve high temperature processing of bioactive glasses and can also be used to control or tailor ion release.

Keywords: ion release; MAE; lithium; potassium; bioactive glass


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About the article

Received: 2016-08-31

Accepted: 2016-11-21

Published Online: 2016-12-14

Citation Information: Biomedical glasses, Volume 2, Issue 1, ISSN (Online) 2299-3932, DOI: https://doi.org/10.1515/bglass-2016-0012.

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© 2016 D. S. Brauer et al.. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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