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Atmospheric pollution in Kosovo is associated with increased DNA damage in the human population

Avdulla J. Alija
  • Corresponding author
  • Department of Biology, University of Prishtina, Xhorxh Bush, n.n.,10000, Prishtina, Kosovo
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/ Fisnik Asllani
  • Corresponding author
  • Department of Biology, University of Prishtina, Xhorxh Bush, n.n.,10000, Prishtina, Kosovo
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/ Ismet D. Bajraktari
  • Corresponding author
  • Department of Biology, University of Prishtina, Xhorxh Bush, n.n.,10000, Prishtina, Kosovo
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/ Andrew Richard Collins
  • Corresponding author
  • Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, PB 1046 Blindern, 0316 Oslo, Norway
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/ Shemsedin Dreshaj
  • Corresponding author
  • Faculty of Medicine, University of Prishtina, Xhorxh Bush Street, n.n.,10000, Prishtina, Kosovo
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/ Nikolaus Bresgen
  • Corresponding author
  • Department of Cell Biology, University of Salzburg, Hellbrunnerstr. 34, A-5020 Salzburg, Austria
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/ Peter M. Eckl
  • Corresponding author
  • Department of Cell Biology, University of Salzburg, Hellbrunnerstr. 34, A-5020 Salzburg, Austria
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Published Online: 2016-01-25 | DOI: https://doi.org/10.1515/bimo-2015-0006

Abstract:

In order to assess DNA damage associated with exposure to environmental pollution in two polluted sites and one control site in Kosovo, whole blood samples were collected from volunteers in two polluted areas (Kastriot/ Obiliq - lignite-based power plants and lignite mines - and Drenas/Gllogovc - Ferronikeli smelting plant) as well as from Peja, representing an unpolluted area. White blood cells were isolated, and DNA damage was analyzed by the alkaline comet assay. Significantly higher levels of DNA damage (strand breaks) were found in white blood cells from subjects living in the polluted areas compared with residents of the unpolluted city, indicating a potential threat to human health.

Keywords : Comet Assay; DNA damage; Environmental pollution; Kosovo

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About the article

Received: 2015-10-09

Accepted: 2015-12-14

Published Online: 2016-01-25


Citation Information: Biomonitoring, Volume 2, Issue 1, ISSN (Online) 2300-4606, DOI: https://doi.org/10.1515/bimo-2015-0006.

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© 2015 Avdulla J. Alija, et al.. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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