Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Open Life Sciences

formerly Central European Journal of Biology

Editor-in-Chief: Ratajczak, Mariusz


IMPACT FACTOR 2018: 0.504
5-year IMPACT FACTOR: 0.583

CiteScore 2018: 0.63

SCImago Journal Rank (SJR) 2018: 0.266
Source Normalized Impact per Paper (SNIP) 2018: 0.311

ICV 2017: 154.48

Open Access
Online
ISSN
2391-5412
See all formats and pricing
More options …
Volume 9, Issue 7

Issues

Volume 10 (2015)

Chemical composition, antimicrobial, antioxidative and anticholinesterase activity of Satureja Montana L. ssp montana essential oil

Tatjana Mihajilov-Krstev / Dragan Radnović / Dušanka Kitić / Vesna Jovanović / Violeta Mitić / Zorica Stojanović-Radić / Bojan Zlatković
Published Online: 2014-04-30 | DOI: https://doi.org/10.2478/s11535-014-0298-x

Abstract

The present study investigates the chemical compositions of three Satureja montana L. ssp montana essential oils and correlates chemical variability with biological activities. GC/MS analysis showed that with an increase in altitude (100–500–800 m), a higher content of linalool, terpinen-4-ol and cis-sabinene hydrate was found, while the percentage of phenolic compounds, thymol and carvacrol decreased. Antimicrobial activity of the essential oils was tested against 7 fungal and 23 bacterial strains. The essential oil characterized by the highest content of phenols and alcohols exhibited the highest antimicrobial potential. The correlation analysis showed that the major carriers of the obtained antioxidant activity are oxygenated monoterpenes. All essential oils inhibited human serum cholinesterase activity. High antimicrobial potential, together with moderate antioxidant capacity and strong inhibition of human serum cholinesterase, classifies S. montana essential oil as a natural source of compounds that can be used in the treatment of foodborne and neurological diseases, wound and other infections, as well as for general health improvement.

Keywords: Satureja montana L. ssp montana; Essential oil; Antimicrobial activity; Antioxidant activity; Cholinesterase inhibiton

  • [1] Redžić S., Wild edible plants and their traditional use in the human nutrition in Bosnia-Herzegovina, Free Radic. Res., 2006, 45, 189–232 Google Scholar

  • [2] Leporatti M.L., Ivancheva S., Preliminary comparative analysis of medicinal plants used in the traditional medicine of Bulgaria and Italy, J. Ethnopharmacol., 2003, 87, 123–142 http://dx.doi.org/10.1016/S0378-8741(03)00047-3CrossrefGoogle Scholar

  • [3] Zavatti M., Zanoli P., Benelli A., Rivasi M., Baraldi C., Baraldi M., Experimental study on Satureja montana as a treatment for premature ejaculation, J. Ethnopharmacol., 2011, 133, 2629–633 http://dx.doi.org/10.1016/j.jep.2010.10.058CrossrefGoogle Scholar

  • [4] Ćavar S., Maksimović M., Šolić M., Jerković-Mujkić E., Bešta R., Chemical composition and antioxidant and antimicrobial activity of two Satureja essential oils, Food Chem., 2008, 111, 648–653 http://dx.doi.org/10.1016/j.foodchem.2008.04.033CrossrefGoogle Scholar

  • [5] Radonić A., Miloš M., Chemical Composition and In Vitro Evaluation of Antioxidant Effect of Free Volatile Compounds from Satureja montana L., Free Radic. Res., 2003, 37, 673–679 http://dx.doi.org/10.1080/1071576031000105643CrossrefGoogle Scholar

  • [6] Skočibušić M., Bežić N., Chemical composition and antidiarrhoeal activities of winter savory (Satureja montana L.) Essential Oil, Pharm. Biol., 2003, 41, 622–626 http://dx.doi.org/10.1080/13880200390502180CrossrefGoogle Scholar

  • [7] Skočibušić M., Bežić N., Chemical composition and antimicrobial variability of Satureja montana L. essential oils produced during ontogenesis, J. Essent. Oil. Res., 2004, 16, 387–391 http://dx.doi.org/10.1080/10412905.2004.9698751CrossrefGoogle Scholar

  • [8] Oussalah M., Caillet S., Saucier L., Lacroix M., Inhibitory effects of selected plant essential oils on the growth of four pathogenic bacteria: E. coli O157:H7, Salmonella typhimurium, Staphylococcus aureus and Listeria monocytogenes, Food Control, 2007, 18, 414–420 http://dx.doi.org/10.1016/j.foodcont.2005.11.009CrossrefGoogle Scholar

  • [9] Carramiñana J.J., Rota C., Burillo J., Herrera A., Antibacterial efficiency of spanish Satureja Montana essential oil against Listeria monocytogenes among natural flora in minced pork, J. Food Protect, 2008, 71, 502–508 CrossrefGoogle Scholar

  • [10] Nedorostova L., Kloucek P., Kokoska L., Stolcova M., Pulkrabek J., Antimicrobial properties of selected essential oils in vapor phase against foodborne bacteria, Food Control, 2009, 20, 157–160 http://dx.doi.org/10.1016/j.foodcont.2008.03.007CrossrefGoogle Scholar

  • [11] Ciani M., Menghini L., Mariani F., Pagiotii R., Menghini A., Fatichenti F., Antimicrobial properties of essential oil of Satureja montana L., on pathogenic and spoilage yeasts, Biotechnol. Lett., 2000, 22, 1007–1010 http://dx.doi.org/10.1023/A:1005649506369CrossrefGoogle Scholar

  • [12] Lampronti I., Saab A.M., Gambari R., Antiproliferative activity of essential oils derived from plants belonging to the Magnoliophyta division, Int. J. Oncol., 2006, 29, 989–995 Google Scholar

  • [13] Prieto J.M., Iacopini P., Cioni P., Chericoni S., In vitro activity of the essential oils of Origanum vulgare, Satureja montana and their main constituents in peroxynitrite-induced oxidative processes, Food Chem., 2007, 104, 889–895 http://dx.doi.org/10.1016/j.foodchem.2006.10.064CrossrefGoogle Scholar

  • [14] Slavkovska V., Jančić J., Bojović S., Milosavljević S., Đoković D., Variability of essential oils of Satureja montana L. and Satureja kitaibelii Wierzb. ex Heuff. from the central part of the Balkan peninsula, Phytochem., 2001, 57, 71–76 http://dx.doi.org/10.1016/S0031-9422(00)00458-1CrossrefGoogle Scholar

  • [15] Miloš M., Radonić A., Bežić N., Dunkić V., Localities and seasonal variations in the chemical composition of essential oils of Satureja montana L. and S. cuneifolia Ten., Flavour. Fragr. J., 2001, 16, 157–160 Google Scholar

  • [16] Ibraliu A., Dhillon B.S., Faslia N., Stich B., Variability of essential oil composition in Albanian accessions of Satureja montana L., J. Med. Plants. Res., 2010, 4, 1359–1364 Google Scholar

  • [17] Mastelić J., Jerković I., Gas chromatography-mass spectrometry analysis of free and glycoconjugated aroma compounds of seasonally collected Satureja montana L., Food Chem., 2003, 80, 135–140 http://dx.doi.org/10.1016/S0308-8146(02)00346-1CrossrefGoogle Scholar

  • [18] Šilić Č., Monograph of the genera Satureja L. Calamintha Miller, Micromeria Bentham, Acinos Miller and Clinopodium L. in flora of Yugoslavia [Monografija rodova Satureja L. Calamintha Miller, Micromeria Bentham, Acinos Miller i Clinopodium L. u flori Jugoslavije], Zemaljski Muzej BiH, Sarajevo, 1979 Google Scholar

  • [19] Bežić N., Šamanić I., Dunkić V., Besendorfer V., Puizina J., Essential Oil Composition and internal transcribed spacer (ITS) sequence variability of four south-Croatian Satureja species (Lamiaceae), Molecules, 2009, 14, 925–938 http://dx.doi.org/10.3390/molecules14030925CrossrefGoogle Scholar

  • [20] Clevenger J.P., Content o essential oil in plants, American Perfumer and Essential Oil Review, 1928, 23, 467–503 Google Scholar

  • [21] Adams R.P., Identification of essential oil components by gas hromatography/mass spectrometry. 4th Ed., Allured Publishing Corporation, Carol Stream, IL, 2007 Google Scholar

  • [22] Mihajilov-Krstev T., Radnović D., Kitić D., Zlatković B., Ristić M., Branković S., Chemical composition and antimicrobial activity of Satureja hortensis L. essential oil., Cent. Eur. J. Biol., 2009, 4, 411–416 http://dx.doi.org/10.2478/s11535-009-0027-zCrossrefGoogle Scholar

  • [23] Kulišić T., Radonić A., Katalinić V., Miloš M., Use of different methods for testing antioxidative activity of oregano essential oil, Food Chem., 2004, 85, 633–640 http://dx.doi.org/10.1016/j.foodchem.2003.07.024CrossrefGoogle Scholar

  • [24] Stojanović G., Stojanović I., Stankov-Jovanović V., Mitić V., Kostić D., Reducing power and radical scavenging activity of four Parmeliaceae species, Cent. Eur. J. Biol., 2010, 5, 808–813 http://dx.doi.org/10.2478/s11535-010-0090-5CrossrefGoogle Scholar

  • [25] Re R., Pellegrini N., Proteggente A., Pannula A., Yang M., Rice-Evans C., Antioxidant activity applying an improved abts radical cation decolorization assay, Free Radic. Biol. Med., 1999, 26, 1231–1237 http://dx.doi.org/10.1016/S0891-5849(98)00315-3CrossrefGoogle Scholar

  • [26] Sanchez-Moreno C., Methods used to evaluate the free radical scavenging activity in foods and biological systems, Food Sci. Technol. Int., 2002, 8, 121–137 http://dx.doi.org/10.1177/1082013202008003770CrossrefGoogle Scholar

  • [27] Stankov-Jovanović V.P., Nikolić-Mandić S.D., Mandić Lj.M., Mitić V.D., Modification of the kinetic determination of pancuronium bromide based on its inhibitory effect on cholinesterase, J. Clin.Lab. Anal., 2007, 21, 124–131 http://dx.doi.org/10.1002/jcla.20162CrossrefGoogle Scholar

  • [28] Hadian J., Tabatabaei S.M.F., Naghavi M.R., Jamzad Z., Ramak-Masoumi T., Genetic diversity of Iranian accessions of Satureja hortensis L. based on horticultural traits and RAPD markers, Sci. Hortic., 2008, 115, 196–202 http://dx.doi.org/10.1016/j.scienta.2007.08.007CrossrefGoogle Scholar

  • [29] Dunkić V., Bezić N., Vuko E., Cukrov D., Antiphytoviral Activity of Satureja montana L. ssp. variegata (Host) P. W. Ball Essential Oil and Phenol Compounds on CMV and TMV, Molecules, 2010, 15, 6713–6721 http://dx.doi.org/10.3390/molecules15106713CrossrefGoogle Scholar

  • [30] Angelini L.G., Carpanese G., Cioni P.L., Morelli I., Macchia M., Flamini G., Essential oils from Mediterranean Lamiaceae as weed germination inhibitors, J. Agric. Food Chem., 2003, 51, 6158–6164 http://dx.doi.org/10.1021/jf0210728CrossrefGoogle Scholar

  • [31] Nikaido H., Prevention of drugs access to bacterial targets: permeability barriers and active efflux, Science, 1994, 264, 382–388 http://dx.doi.org/10.1126/science.8153625CrossrefGoogle Scholar

  • [32] Dorman H.J.D., Deans S.G., Antimicrobial agents from plants: antibacterial activity of plant volatile oils, J. App. Microbiol., 2000, 88, 308–316 http://dx.doi.org/10.1046/j.1365-2672.2000.00969.xCrossrefGoogle Scholar

  • [33] Zhou F., Ji B., Zhang H., Jiang H., Yang Z., Li J., Li J., Yan W., The antibacterial effect of cinnamaldehyde, thymol, carvacrol and their combinations against the foodborne pathogen Salmonella typhimurium, J. Food Safety, 2007, 27, 124–133 http://dx.doi.org/10.1111/j.1745-4565.2007.00064.xCrossrefGoogle Scholar

About the article

Published Online: 2014-04-30

Published in Print: 2014-07-01


Citation Information: Open Life Sciences, Volume 9, Issue 7, Pages 668–677, ISSN (Online) 2391-5412, DOI: https://doi.org/10.2478/s11535-014-0298-x.

Export Citation

© 2014 Versita Warsaw. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

[1]
I. T. Ushakova, L. V. Bespalko, V. A. Kharchenko, A. V. Molchanova, and G. D. Levko
Vegetable crops of Russia, 2019, Number 3, Page 25
[2]
María Ibáñez and María Blázquez
Plants, 2018, Volume 7, Number 4, Page 79
[3]
Monica Scognamiglio, Brigida D’Abrosca, Assunta Esposito, and Antonio Fiorentino
Journal of Analytical Methods in Chemistry, 2015, Volume 2015, Page 1

Comments (0)

Please log in or register to comment.
Log in