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Biomolecular Concepts

Editor-in-Chief: Di Cera, Enrico


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CiteScore 2017: 2.50

SCImago Journal Rank (SJR) 2017: 0.861
Source Normalized Impact per Paper (SNIP) 2017: 0.722

ICV 2017: 131.30

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1868-503X
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Volume 4, Issue 1

Issues

The meaning of aluminium exposure on human health and aluminium-related diseases

Guido Crisponi
  • Corresponding author
  • Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria, I-09042 Monserrato Cagliari, Italy
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/ Daniela Fanni
  • Dipartimento di Scienze Chirurgiche, Sez. Anatomia Patologica, Via Ospedale 46, I-09124 Cagliari, Italy
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/ Clara Gerosa
  • Dipartimento di Scienze Chirurgiche, Sez. Anatomia Patologica, Via Ospedale 46, I-09124 Cagliari, Italy
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/ Sonia Nemolato
  • Dipartimento di Scienze Chirurgiche, Sez. Anatomia Patologica, Via Ospedale 46, I-09124 Cagliari, Italy
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/ Valeria M. Nurchi
  • Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria, I-09042 Monserrato Cagliari, Italy
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/ Miriam Crespo-Alonso
  • Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria, I-09042 Monserrato Cagliari, Italy
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/ Joanna I. Lachowicz
  • Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria, I-09042 Monserrato Cagliari, Italy
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/ Gavino Faa
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Published Online: 2013-01-05 | DOI: https://doi.org/10.1515/bmc-2012-0045

Abstract

The aim of this review is to attempt to answer extremely important questions related to aluminium-related diseases. Starting from an overview on the main sources of aluminium exposure in everyday life, the principal aspects of aluminium metabolism in humans have been taken into consideration in an attempt to enlighten the main metabolic pathways utilised by trivalent metal ions in different organs. The second part of this review is focused on the available evidence concerning the pathogenetic consequences of aluminium overload in human health, with particular attention to its putative role in bone and neurodegenerative human diseases.

Keywords: aluminium; aluminium overload; aluminium-related disease; bone pathology; brain pathology

About the article

Corresponding author: Guido Crisponi, Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria, I-09042 Monserrato Cagliari, Italy


Received: 2012-10-18

Accepted: 2012-11-26

Published Online: 2013-01-05

Published in Print: 2013-02-01


Citation Information: BioMolecular Concepts, Volume 4, Issue 1, Pages 77–87, ISSN (Online) 1868-503X, ISSN (Print) 1868-5021, DOI: https://doi.org/10.1515/bmc-2012-0045.

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