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Biomedical Engineering / Biomedizinische Technik

Joint Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering and the German Society of Biomaterials

Editor-in-Chief: Dössel, Olaf

Editorial Board: Augat, Peter / Habibović, Pamela / Haueisen, Jens / Jahnen-Dechent, Wilhelm / Jockenhoevel, Stefan / Knaup-Gregori, Petra / Lenarz, Thomas / Leonhardt, Steffen / Plank, Gernot / Radermacher, Klaus M. / Schkommodau, Erik / Stieglitz, Thomas / Boenick, Ulrich / Jaramaz, Branislav / Kraft, Marc / Lenthe, Harry / Lo, Benny / Mainardi, Luca / Micera, Silvestro / Penzel, Thomas / Robitzki, Andrea A. / Schaeffter, Tobias / Snedeker, Jess G. / Sörnmo, Leif / Sugano, Nobuhiko / Werner, Jürgen /

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Ahead of print


Volume 57 (2012)

Heart valves from polyester fibers: a preliminary 6-month in vivo study

Antoine Vaesken / Anne Pelle
  • INSERM U1148, Laboratory for Vascular Translational Science, Université Paris 13, Sorbonne Paris Cité, 99 Av. Jean-Baptiste Clément, 93430 Villetaneuse, France
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Graciela Pavon-Djavid
  • INSERM U1148, Laboratory for Vascular Translational Science, Université Paris 13, Sorbonne Paris Cité, 99 Av. Jean-Baptiste Clément, 93430 Villetaneuse, France
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Jeanne Rancic
  • Laboratoire de Recherches Biochirurgicales de la Fondation Alain Carpentier, plate-forme de l’Université Paris Descartes, Paris, France
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Nabil Chakfe / Frederic Heim
  • Corresponding author
  • Laboratoire de Physique et Mécanique Textiles EA 4365, ENSISA, Geprovas, Mulhouse, France, Phone: +33 6 79 77 02 32, Fax: +33 3 89 33 63 39
  • Email
  • Other articles by this author:
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Published Online: 2017-05-03 | DOI: https://doi.org/10.1515/bmt-2016-0242


Transcatheter aortic valve implantation (TAVI) has become a popular alternative technique to surgical valve replacement for critical patients. Biological valve tissue has been used in TAVI procedures for over a decade, with over 150,000 implantations to date. However, with only 6 years of follow up, little is known about the long-term durability of biological tissue. Moreover, the high cost of tissue harvesting and chemical treatment procedures favor the development of alternative synthetic valve leaflet materials. In that context, textile polyester [polyethylene terephthalate (PET)] could be considered as an interesting candidate to replace the biological valve leaflets in TAVI procedures. However, no result is available in the literature about the behavior of textile once in contact with biological tissue in the valve position. The interaction of synthetic textile material with living tissues should be comparable to biological tissue. The purpose of this preliminary work is to compare the in vivo performances of various woven textile PET valves over a 6-month period in order to identify favorable textile construction features. In vivo results indicate that fibrosis as well as calcium deposit can be limited with an appropriate material design.

Keywords: fiber valve; heart valve; TAVI; textile valve; transcatheter valve; valve fibrosis


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About the article

Received: 2016-12-05

Accepted: 2017-03-28

Published Online: 2017-05-03

Citation Information: Biomedical Engineering / Biomedizinische Technik, 20160242, ISSN (Online) 1862-278X, ISSN (Print) 0013-5585, DOI: https://doi.org/10.1515/bmt-2016-0242.

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