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Bulletin of the Veterinary Institute in Pulawy

The Journal of National Veterinary Research Institute in Pulawy

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IMPACT FACTOR 2016: 0.462

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2300-3235
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Morphology of Human Glioblastoma Model Cultured in Ovo

Maciej Szmidt
  • Department of Morphological Science, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776 Warszawa, Poland
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/ Kaja Urbańska
  • Department of Morphological Science, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776 Warszawa, Poland
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/ Marta Grodzik
  • Department of Animal Nutrition and Feed, Faculty of Animal Science, Warsaw University of Life Sciences-SGGW, 02-786 Warszawa, Poland
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/ Piotr Orłowski
  • Department of Animal Nutrition and Feed, Faculty of Animal Science, Warsaw University of Life Sciences-SGGW, 02-786 Warszawa, Poland
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/ Ewa Sawosz
  • Department of Animal Nutrition and Feed, Faculty of Animal Science, Warsaw University of Life Sciences-SGGW, 02-786 Warszawa, Poland
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/ Mateusz Wierzbicki
  • Department of Animal Nutrition and Feed, Faculty of Animal Science, Warsaw University of Life Sciences-SGGW, 02-786 Warszawa, Poland
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/ Paweł Sysa
  • Department of Morphological Science, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776 Warszawa, Poland
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Published Online: 2013-01-17 | DOI: https://doi.org/10.2478/v10213-012-0046-9

Abstract

The aim of this study was the morphological characterisation of glioblastoma multiforme tumour grown in ovo. Tumour cells (U-87 MG) were implanted on the chorioallantoic membrane of chicken egg. The structural features of cultured tumours resembled the spontaneous glioblastoma multiforme; however, the differences were also indicated. Our results confirm applicability of in ovo culture in tumour genesis studies. The described novel model may be profoundly helpful for the future research on molecular mechanisms of tumour growth inhibition.

Keyword : glioblastoma multiforme; U-87 MG; in ovo model; choriaoallantoic membrane.

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About the article

Published Online: 2013-01-17

Published in Print: 2012-06-01


Citation Information: Bulletin of the Veterinary Institute in Pulawy, ISSN (Print) 0042-4870, DOI: https://doi.org/10.2478/v10213-012-0046-9.

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