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Bulletin of the Veterinary Institute in Pulawy

The Journal of National Veterinary Research Institute in Pulawy

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Immunoreactivity of S100β protein in the hippocampus of chinchilla

Aleksandra Krawczyk
  • Corresponding author
  • Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin, Poland
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/ Karol Rycerz
  • Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin, Poland
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/ Radosław Szalak
  • Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin, Poland
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/ Jadwiga Jaworska-Adamu
  • Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin, Poland
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Published Online: 2014-03-25 | DOI: https://doi.org/10.2478/bvip-2014-0017


The aim of the study was to investigate S100β protein in astrocytes of CA1 and CA3 areas of the hippocampus proper and the dentate gyrus with the hilus yet undefined in mature males of chinchilla. The presence of S100β was determined using indirect immunohistochemical peroxidase-antiperoxidase method with specific monoclonal antibody against this protein. Most of the S100β-positive cells were detected in the subgranular zone of the dentate gyrus and in the middle part of the hilus. In CA3 area, it was found that the most numerous cells with S100β are in stratum radiatum. In CA1 area, there were single astrocytes expressing this protein. This data demonstrates species differences and a large quantity of S100β immunoreactive cells in the subgranular zone of the dentate gyrus of chinchilla, which may be associated with structural reorganisation of the hippocampus and with neurogenesis, learning, and memorising process dependent on the hippocampus.

Keywords: chinchilla; S100β protein; immunoreactivity; astrocytes; hippocampus.


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About the article

Published Online: 2014-03-25

Published in Print: 2014-03-01

Citation Information: Bulletin of the Veterinary Institute in Pulawy, Volume 58, Issue 1, Pages 105–109, ISSN (Online) 2300-3235, DOI: https://doi.org/10.2478/bvip-2014-0017.

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