Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter

IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

See all formats and pricing
More options …
Volume 36, Issue 6


Antigenic Definition of Cardiac Troponin I

Catherine Larue / Gaëlle Ferrieres / Michel Laprade / Charles Calzolari / Claude Granier
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.1998.061


The presence of cardiac troponin I in the serum is now considered as one of the most specific biochemical markers of acute myocardial infarction. To improve the knowledge of the antigenic properties of cardiac Troponin I, a set of monoclonal antibodies and polyclonal antibodies against human cardiac troponin I has been tested with overlapping peptides covering the cardiac troponin I sequence. The results indicate that N-terminal and C-terminal cardiac troponin I regions were most often recognized by poly- and monoclonal antibodies. These observations are valuable for choosing the best combination of monoclonal antibodies to set up new immunoassays to detect serum cardiac troponin I earlier after myocardial damage, to understand better which forms are released, and finally to propose appropriate cardiac troponin I standards.

About the article

Published Online: 2005-06-01

Published in Print: 1998-06-01

Citation Information: Clinical Chemistry and Laboratory Medicine, Volume 36, Issue 6, Pages 361–365, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.1998.061.

Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Majid Asiabanha Rezaee, Mohammad Javad Rasaee, and Javad Mohammadnejad
Journal of Immunoassay and Immunochemistry, 2017, Volume 38, Number 1, Page 72
Gracey N. Onuoha, E. Kaya Alpar, Brian Dean, Jane Tidman, Daniel Rama, Michel Laprade, and Bernerd Pau
Journal of Orthopaedic Science, 2001, Volume 6, Number 1, Page 11
Mark A Oyama and Philip F Solter
Journal of Veterinary Cardiology, 2004, Volume 6, Number 2, Page 17
B Toussaint, MP Coulhon, H Mentec, and D Duchassing
Immuno-analyse & Biologie Spécialisée, 2000, Volume 15, Number 1, Page 19
L.Kristin Newby, Britta U. Goldmann, and E.Magnus Ohman
Journal of the American College of Cardiology, 2003, Volume 41, Number 4, Page S31

Comments (0)

Please log in or register to comment.
Log in