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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

12 Issues per year


IMPACT FACTOR increased in 2015: 3.017
Rank 5 out of 30 in category Medical Laboratory Technology in the 2014 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2015: 0.873
Source Normalized Impact per Paper (SNIP) 2015: 0.982
Impact per Publication (IPP) 2015: 2.238

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ISSN
1437-4331
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Laboratory Screening for Erythropoietin Abuse in Sport: an Emerging Challenge

Giuseppe Lippi / Giancesare Guidi
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2000.003

Abstract

The growing diffusion of banned practice to improve the athletic performances is forcing clinical laboratories to identify and standardize reliable assays to detect potential unfairness. Among the doping practices, the use of recombinant human erythropoietin is becoming fairly popular, due to simplicity and safeties of administration and troublesome detection. The heterogeneous response rate, the presence of a little but significant amount of naturally occurring hormone, the short half-life exhibited by recombinant human erythropoietin and the lack of standardization of commercial assays appear the main problems to overcome. Aim of the present article is to provide a critical review of some of the more widespread laboratory techniques currently available for the screening for erythropoietin abuse in sport.


Published Online: 2005-06-01

Published in Print: 2000-01-08


Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 38, Issue 1, Pages 13–19, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2000.003, June 2005

Citing Articles

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[1]
Giuseppe Lippi, Massimo Franchini, Gian Luca Salvagno, and Gian Cesare Guidi
Critical Reviews in Clinical Laboratory Sciences, 2006, Volume 43, Number 4, Page 349
[2]
M. Saugy, C. Lundby, and N. Robinson
British Journal of Sports Medicine, 2014, Volume 48, Number 10, Page 827
[3]
W. Jelkmann
Journal of Endocrinological Investigation, 2003, Volume 26, Number 9, Page 832
[4]
Giuseppe Lippi, Franco Manzato, Massimo Franchini, and Giancesare Guidi
American Heart Journal, 2002, Volume 144, Number 5, Page A6
[5]
Roger S. Riley, Jonathan M. Ben-Ezra, Ann Tidwell, and Gina Romagnoli
Hematology/Oncology Clinics of North America, 2002, Volume 16, Number 2, Page 373
[6]
Mauro Magnani, Dario Corsi, Marzia Bianchi, Mirko Paiardini, Luca Galluzzi, Elisa Gargiullo, Attilio Parisi, and Fabio Pigozzi
Blood Cells, Molecules, and Diseases, 2001, Volume 27, Number 3, Page 559
[7]
Thomas L. Pommering
Pediatric Clinics of North America, 2007, Volume 54, Number 4, Page 691
[8]
Michele Samaja
High Altitude Medicine & Biology, 2001, Volume 2, Number 2, Page 155
[9]
Giuseppe Lippi, Giorgio Brocco, Massimo Franchini, Federico Schena, and Giancesare Guidi
Clinical Chemistry and Laboratory Medicine, 2004, Volume 42, Number 6
[10]
Christina Tsitsimpikou, Demetrios Kouretas, Konstantinos Tsarouhas, Kenneth Fitch, Demetrios A Spandidos, and Aristides Tsatsakis
Therapeutic Drug Monitoring, 2011, Volume 33, Number 1, Page 3
[11]
Giuseppe Lippi and Massimo Franchini
European Journal of Applied Physiology, 2010, Volume 108, Number 2, Page 411
[12]
Jordi Segura, José A. Pascual, and Ricardo Gutiérrez-Gallego
Analytical and Bioanalytical Chemistry, 2007, Volume 388, Number 7, Page 1521
[13]
Roger S. Riley, Jonathan M. Ben-Ezra, MT (ASCP), and Ann Tidwell
Laboratory Medicine, 2001, Volume 32, Number 10, Page 599
[14]
Roger S. Riley, Jonathan M. Ben-Ezra, Rajat Goel, and Ann Tidwell
Journal of Clinical Laboratory Analysis, 2001, Volume 15, Number 5, Page 267

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